Table showing the number of alleles, proteins and nulls in the IPD-IMGT/HLA Database named as of March 2025.
| Numbers of HLA Alleles | |
|---|---|
| HLA class I alleles | 28683 |
| HLA class II alleles | 12877 |
| HLA alleles | 41560 |
| Other non-HLA alleles | 1024 |
| Number of confidential alleles | 0 |
| HLA class I | ||||||
|---|---|---|---|---|---|---|
| Gene | A | B | C | E | F | G |
| Alleles | 8640 | 10446 | 8743 | 378 | 116 | 177 |
| Proteins | 5053 | 6223 | 4823 | 142 | 22 | 52 |
| Nulls | 457 | 377 | 396 | 10 | 3 | 6 |
| HLA class I - Pseudogenes | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gene | H | J | K | L | N | P | R | S | T | U | V | W | Y | |
| Alleles | 82 | 33 | 7 | 6 | 5 | 5 | 2 | 7 | 9 | 7 | 4 | 13 | 3 | |
| Proteins | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Nulls | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| HLA class II | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gene | DRA | DRB | DQA1 | DQA2 | DQB1 | DQB2 | DPA1 | DPA2 | DPB1 | DPB2 | DMA | DMB | DOA | DOB |
| Alleles | 80 | 4898 | 890 | 42 | 2858 | 41 | 779 | 6 | 2859 | 7 | 76 | 113 | 130 | 98 |
| Proteins | 18 | 3209 | 453 | 11 | 1704 | 9 | 378 | 0 | 1638 | 0 | 9 | 9 | 16 | 19 |
| Nulls | 0 | 221 | 21 | 0 | 124 | 1 | 33 | 0 | 148 | 0 | 0 | 0 | 1 | 1 |
| HLA class II - DRB Alleles | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Gene | DRB1 | DRB2 | DRB3 | DRB4 | DRB5 | DRB6 | DRB7 | DRB8 | DRB9 |
| Alleles | 3825 | 1 | 546 | 292 | 221 | 4 | 2 | 1 | 6 |
| Proteins | 2474 | 0 | 407 | 171 | 157 | 0 | 0 | 0 | 0 |
| Nulls | 136 | 0 | 28 | 30 | 27 | 0 | 0 | 0 | 0 |
| Other non-HLA Genes | ||||||
|---|---|---|---|---|---|---|
| Gene | HFE | MICA | MICB | TAP1 | TAP2 | |
| Alleles | 6 | 586 | 307 | 19 | 106 | |
| Proteins | 4 | 278 | 49 | 11 | 13 | |
| Nulls | 0 | 9 | 25 | 1 | 0 | |
Last updated: 14-Apr-2025