Table showing the number of alleles, proteins and nulls in the IPD-IMGT/HLA Database named as of June 2025.
| Numbers of HLA Alleles | |
|---|---|
| HLA class I alleles | 28983 |
| HLA class II alleles | 13210 |
| HLA alleles | 42193 |
| Other non-HLA alleles | 1032 |
| Number of confidential alleles | 1 |
| HLA class I | ||||||
|---|---|---|---|---|---|---|
| Gene | A | B | C | E | F | G |
| Alleles | 8715 | 10584 | 8807 | 381 | 122 | 187 |
| Proteins | 5092 | 6311 | 4858 | 144 | 27 | 58 |
| Nulls | 462 | 385 | 402 | 10 | 3 | 6 |
| HLA class I - Pseudogenes | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gene | H | J | K | L | N | P | R | S | T | U | V | W | Y | |
| Alleles | 86 | 33 | 7 | 6 | 5 | 5 | 2 | 7 | 9 | 7 | 4 | 13 | 3 | |
| Proteins | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Nulls | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| HLA class II | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gene | DRA | DRB | DQA1 | DQA2 | DQB1 | DQB2 | DPA1 | DPA2 | DPB1 | DPB2 | DMA | DMB | DOA | DOB |
| Alleles | 80 | 5083 | 910 | 42 | 2896 | 41 | 803 | 6 | 2890 | 7 | 85 | 124 | 140 | 103 |
| Proteins | 18 | 3296 | 461 | 11 | 1718 | 9 | 390 | 0 | 1658 | 0 | 10 | 9 | 17 | 20 |
| Nulls | 0 | 233 | 23 | 0 | 124 | 1 | 34 | 0 | 151 | 0 | 0 | 0 | 1 | 1 |
| HLA class II - DRB Alleles | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Gene | DRB1 | DRB2 | DRB3 | DRB4 | DRB5 | DRB6 | DRB7 | DRB8 | DRB9 |
| Alleles | 3856 | 1 | 634 | 328 | 251 | 4 | 2 | 1 | 6 |
| Proteins | 2499 | 0 | 438 | 187 | 172 | 0 | 0 | 0 | 0 |
| Nulls | 138 | 0 | 31 | 35 | 29 | 0 | 0 | 0 | 0 |
| Other non-HLA Genes | ||||||
|---|---|---|---|---|---|---|
| Gene | HFE | MICA | MICB | TAP1 | TAP2 | |
| Alleles | 6 | 589 | 312 | 19 | 106 | |
| Proteins | 4 | 279 | 53 | 11 | 13 | |
| Nulls | 0 | 9 | 25 | 1 | 0 | |
Last updated: 14-Jul-2025