HLA Alleles

Assigned as of April 2014

There are currently 11,389 HLA and related alleles described by the HLA nomenclature and included in the IMGT/HLA Database. It is now established procedure for authors to submit the sequences directly to the IMGT/HLA Database for checking and assignment of an official name prior to publication, this avoids the problems associated with renaming published sequences and the confusion of multiple names for the same sequence. The dissemination of new allele names and sequences is of paramount importance in the clinical setting and through the work of the HLA Informatics Group and in collaboration with the European Bioinformatics Institute, we are able to provide public access to the data through the websites http://www.ebi.ac.uk/ipd/imgt/hla/ and here at http://hla.alleles.org. Regular updates to these websites ensure that new and confirmatory sequences are dispersed to the HLA community, and the wider research and clinical communities. The need for reasonably rapid publication of new HLA allele sequences has necessitated an annual meeting of the WHO Nomenclature Committee for Factors of the HLA System. Additionally we now publish monthly HLA nomenclature updates both in journals and online to provide quick and easy access to new sequence information.

Access sequence alignments and files by clicking on the map of the HLA region below

To see sequences and reference information, use the map below to click on the gene whose data interests you. Alternatively, you can access each gene's sequences and reference information directly from this page. The alignments and files provided on hla.alleles.org are based on Release 3.16.0 of the IMGT/HLA Database. A single zipped archive of all the text alignments produced for this release is available from the IMGT/HLA ftp server by clicking this link to download the alignments.

Map of the HLA region of chromosome 6 HLA-DPB HLA-DPA HLA-DOA DMA DMB HLA-Z LMP2 TAP1 LMP7 TAP2 HLA-DOB HLA-DQ HLA-DQB1 HLA-DQA1 HLA-DRB HLA-DRA MICB MICA HLA-S HLA-B HLA-C HLA-E HLA-N HLA-L HLA-F HLA-V HLA-P HLA-G HLA-H HLA-T HLA-K HLA-U HLA-A HLA-W HLA-J  

If you wish to cite these numbers in a publication, please see our citations page for further details on how you can do this.