HLA Alleles Numbers

Assigned as of March 2021

The numbers below represent the number of named alleles for each gene. This number includes alleles that have been named but whose sequences are still confidential. This means that the number of sequences found in some files on this site may differ from the number of sequences indicated in this table. Details of the alleles that are still confidential can be seen in the latest version reports on the IPD-IMGT/HLA Database web site. The numbers below do not include the names of any deleted alleles - further details of deleted alleles can be found here. If you wish to cite these numbers in a publication, please see our citations page for further details.


Numbers of HLA Alleles
HLA Class I Alleles 21,903
HLA Class II Alleles 8,136
HLA Alleles 30,522
Other non-HLA Alleles 483
Number of Confidential Alleles 1
HLA Class I
Gene A B C E F G
Alleles 6,766 7,967 6,620 271 45 82
Proteins 4,064 4,962 3,831 110 6 22
Nulls 344 269 286 7 0 4
HLA Class I - Pseudogenes
Gene H J K L N P S T U V W Y
Alleles 66 27 6 5 5 5 7 8 5 3 11 3
Proteins 0 0 0 0 0 0 0 0 0 0 0 0
Nulls 0 0 0 0 0 0 0 0 0 0 0 0
HLA Class II
Gene DRA DRB DQA1 DQA2 DQB1 DPA1 DPA2 DPB1 DPB2 DMA DMB DOA DOB
Alleles 29 3,701 306 40 1,997 258 5 1,749 6 7 13 12 13
Proteins 2 2,557 143 11 1,303 107 2 1,106 3 4 7 3 5
Nulls 0 155 7 0 86 7 0 88 0 0 0 1 0
HLA Class II - DRB Alleles
Gene DRB1 DRB2 DRB3 DRB4 DRB5 DRB6 DRB7 DRB8 DRB9
Alleles 2,949 1 390 194 155 3 2 1 6
Proteins 2,015 0 293 129 120 0 0 0 0
Nulls 96 0 18 22 19 0 0 0 0
Other non-HLA Genes
Gene HFE MICA MICB TAP1 TAP2
Alleles 6 224 229 12 12
Proteins 6 104 38 6 5
Nulls 0 5 23 1 0