HLA Genes

A Table of Named Genes within the HLA Region

Name Previous equivalents Molecular characteristics
HLA-A - Class I α-chain
HLA-B - Class I α-chain
HLA-C - Class I α-chain
HLA-E E, '6.2' associated with class I 6.2-kB Hind III fragment
HLA-F F, '5.4' associated with class I 5.4-kB Hind III fragment
HLA-G G, '6.0' associated with class I 6.0-kB Hind III fragment
HLA-H H, AR, '12.4' Class I pseudogene associated with 5.4-kB Hind III fragment
HLA-J cda12 Class I pseudogene associated with 5.9-kB Hind III fragment
HLA-K HLA-70 Class I pseudogene associated with 7.0-kB Hind III fragment
HLA-L HLA-92 Class I pseudogene associated with 9.2-kB Hind III fragment
HLA-N HLA-30 Class I gene fragment associated with a 1.7-kB Hind III fragment
HLA-P HLA-90 Class I gene fragment associated with 9.0-kB Hind III fragment
HLA-S HLA-17 Class I gene fragment associated with a 3.0-kB Hind III fragment
HLA-T HLA-16 Class I gene fragment associated with 16.0-kB Hind III fragment
HLA-U HLA-21 Class I gene fragment associated with 2.1-kB Hind III fragment
HLA-V HLA-75 Class I gene fragment associated with 7.5-kB Hind III fragment
HLA-W HLA-80 Class I gene fragment associated with 8.0-kB Hind III fragment
HLA-X HLA-X Class I gene fragment
HLA-Y HLA-BEL/COQ/DEL Class I pseudogene
HLA-Z HLA-Z1 Class I gene fragment located within the HLA Class II region
HLA-DRA DRα DR α-chain
HLA-DRB1 DRβI, DR1B DR β1-chain determining specificities DR1, DR2, DR3, DR4, DR5 etc.
HLA-DRB2 DRβII pseudogene with DR β-like sequences
HLA-DRB3 DRβIII, DR3B DR β3-chain determining DR52 and Dw24, Dw25, Dw26 specificities
HLA-DRB4 DRβIV, DR4B DR β4-chain determining DR53
HLA-DRB5 DRβIII DR β5-chain determining DR51
HLA-DRB6 DRBX, DRBσ DRB pseudogene found on DR1, DR2 and DR10 haplotypes
HLA-DRB7 DRBψ1 DRB pseudogene found on DR4, DR7 and DR9 haplotypes
HLA-DRB8 DRBψ2 DRB pseudogene found on DR4, DR7 and DR9 haplotypes
HLA-DRB9 M4.2 β exon DRB pseudogene, isolated fragment
HLA-DQA1 DQα1, DQ1A DQ α-chain as expressed
HLA-DQB1 DQβ1, DQ1B DQ β-chain as expressed
HLA-DQA2 DXα, DQ2A DQ α-chain-related sequence, not known to be expressed
HLA-DQB2 DXβ, DQ2B DQ β-chain-related sequence, not known to be expressed
HLA-DQB3 DVβ, DQB3 DQ β-chain-related sequence, not known to be expressed
HLA-DOA DZα, DOα, DNA DO α-chain
HLA-DOB DOβ DO β-chain
HLA-DMA RING6 DM α-chain
HLA-DMB RING7 DM β-chain
HLA-DPA1 DPα1, DP1A DP α-chain as expressed
HLA-DPB1 DPβ1, DP1B DP β-chain as expressed
HLA-DPA2 DPα2, DP2A DP α-chain-related pseudogene
HLA-DPB2 DPβ2, DP2B DP β-chain-related pseudogene
HLA-DPA3 DPA3 DP α-chain-related pseudogene
TAP1 ABCB2, RING4, Y3, PSF1 ABC (ATP Binding Cassette) transporter
TAP2 ABCB3, RING11, Y1, PSF2 ABC (ATP Binding Cassette) transporter
PSMB9 LMP2, RING12 Proteasome-related sequence
PSMB8 LMP7, RING10 Proteasome-related sequence
MICA MICA, PERB11.1 Class I chain-related gene
MICB MICB, PERB11.2 Class I chain-related gene
MICC MICC, PERB11.3 Class I chain-related pseudogene
MICD MICD, PERB11.4 Class I chain-related pseudogene
MICE MICE, PERB11.5 Class I chain-related pseudogene