Nomenclature for Factors of the HLA System

April 2017

Compiled by Steven G. E. Marsh for the WHO Nomenclature Committee for Factors of the HLA System.

Published In:

The following sequences have been submitted to the Nomenclature Committee since the March 2017 nomenclature update and, following agreed policy, have been assigned official allele designations. Full details of all sequences will be published in a forthcoming report.

Below are listed the newly assigned sequences (Table 1) and confirmations of previously reported sequences (Table 2). The accession number of each sequence is given and these can be used to retrieve the sequence files from the EMBL, GenBank or DDBJ data libraries. Although accession numbers have been assigned by the data-libraries and most sequences are already available, there is still the possibility that an author may not yet have allowed the sequence to be released; in such a case you will have to contact the submitting author directly. Additional information pertaining to new sequences is often included in the publications describing these alleles; a listing of recent publications that describe new HLA sequences is given in Table 3.

All new and confirmatory sequences should now be submitted directly to the WHO Nomenclature Committee for Factors of the HLA System via the IMGT/HLA Database using the sequence submission tool provided (2). The IMGT/HLA Database may be accessed via the world wide web at :

Table 1: New Sequences

SequenceCell identificationAccession numberSubmitting author
A*02:01:131SEV170210_8373982KY658455,Oh-Joong Kwon, Seoul, South Korea
A*02:07:0917011KY927933,Bo Jing Wang, Beijing, China
A*02:684D012006LT715984,Edward KL Yang, Hualien, Taiwan
A*02:685016208927LT838206,Sarah Colom, La Tronche, France
A*02:686016191323LT838209,Sarah Colom, La Tronche, France
A*02:687CHA16-650KY929521,Ji Young Huh, Sungnam-si, South Korea
A*11:263D353776LT838274,Edward KL Yang, Hualien, Taiwan
A*24:20:01:02T324LC257695,Takashi Shiina, Isehara, Japan
A*29:100016249291LT838205,Sarah Colom, La Tronche, France
A*30:1189000615169747KY745906,Faming Zhu, Hangzhou, China
A*32:102015938972LT838195,Sarah Colom, La Tronche, France
B*08:181UA2016TP2977LT707070,Mats Bengtsson, Uppsala, Sweden
B*15:428T137LC257712,Takashi Shiina, Isehara, Japan
B*18:137015940578LT838211,Sarah Colom, La Tronche, France
B*27:02:04CN_36515,CN_39545KY594041,Lucia Assunta Longa, Cuneo, Italy
B*27:05:02:05JM44LC257714,Takashi Shiina, Isehara, Japan
B*35:344016229754LT838212,Sarah Colom, La Tronche, France
B*39:01:03:02T106LC257720,Takashi Shiina, Isehara, Japan
B*40:03:01:02T420LC257727,Takashi Shiina, Isehara, Japan
B*40:356CXD0097KY774655,Jian Tang, Jinan, China
B*40:3575791600402KY865355,Faming Zhu, Hangzhou, China
B*44:02:47016214757LT838210,Sarah Colom, La Tronche, France
B*44:03:01:10JM06LC257731,Takashi Shiina, Isehara, Japan
B*46:729000615170050KY696709,Faming Zhu, Hangzhou, China
B*48:01:01:02T138LC257734,Takashi Shiina, Isehara, Japan
B*49:01:09016198646LT838215,Sarah Colom, La Tronche, France
B*51:224015956440LT838213,Sarah Colom, La Tronche, France
B*53:01:12016207751LT838214,Sarah Colom, La Tronche, France
B*57:01:24016227123LT838216,Sarah Colom, La Tronche, France
C*02:02:02:13BY01459KY626048,Carolyn K Hurley, Washington DC, USA
C*03:99:02DKMS-LSL-C-949LN999637,DKMS Life Sciences Lab, Dresden, Germany
C*07:591015849899LT838225,Sarah Colom, La Tronche, France
C*08:01:20afn548KY938880,Mingrui Huo, Beijing, China
C*12:02:02:03BY01445KY622046,Carolyn K Hurley, Washington DC, USA
C*12:214UC5681KY906102,Xiaodong Mo, Shenzhen, China
C*14:87R44801LT715985,Edward KL Yang, Hualien, Taiwan
C*17:37H4E3KY859857,Yvonne Thorstenson, Mountain View, USA
F*01:01:01:13KT17KY704496,Mehdi Alizadeh, Rennes, Frances
G*01:01:01:08DUCAFKY704495,Mehdi Alizadeh, Rennes, Frances
DRB1*04:05:01:02JM15LC257779,Takashi Shiina, Isehara, Japan
DRB1*04:05:01:03T300LC257780,Takashi Shiina, Isehara, Japan
DRB1*04:07:06078259LT555516,Ute Geigenmuller, Westborough, USA
DRB1*08:02:01:02JM38LC257786,Takashi Shiina, Isehara, Japan
DRB1*09:01:02:02T106LC257790,Takashi Shiina, Isehara, Japan
DRB1*09:31DML-05KX810863,Edward KL Yang, Hualien, Taiwan
DRB1*10:01:01:03T138LC257791,Takashi Shiina, Isehara, Japan
DRB1*11:01:01:03T119LC257792,Takashi Shiina, Isehara, Japan
DRB1*11:01:01:04JM15LC257793,Takashi Shiina, Isehara, Japan
DRB1*12:01:01:04JM21LC257794,Takashi Shiina, Isehara, Japan
DRB1*12:01:01:05T119LC257795,Takashi Shiina, Isehara, Japan
DRB1*12:02:01:02KB74UKLC218002,Uma Kanga, New Delhi, India
DRB1*12:02:01:03T067LC257797,Takashi Shiina, Isehara, Japan
DRB1*12:02:01:04T021LC257798,Takashi Shiina, Isehara, Japan
DRB1*12:67408443LT715986,Edward KL Yang, Hualien, Taiwan
DRB1*13:237BY01467KY653747,Carolyn K Hurley, Washington DC, USA
DRB3*01:01:07063298LT555525,Ute Geigenmuller, Westborough, USA
DRB3*01:01:08097357LT555526,Ute Geigenmuller, Westborough, USA
DRB3*02:02:07094654LT555527,Ute Geigenmuller, Westborough, USA
DRB3*02:02:08060363LT555529,Ute Geigenmuller, Westborough, USA
DRB3*02:02:09TAJA829106ANLT837967,Steven GE Marsh, London, United Kingdom
DQB1*02:95BY01465 KY653745,Carolyn K Hurley, Washington DC, USA
DQB1*02:96N276887KY856762,Vera Balz, D,sseldorf, Germany
DQB1*03:01:01:06RMLKY704494,Mehdi Alizadeh, Rennes, Frances
DQB1*03:01:01:07KB62UKLC217997,Uma Kanga, New Delhi, India
DQB1*03:01:01:08100379,226489,276077,291441,293045KY856763,Vera Balz, D,sseldorf, Germany
DQB1*03:01:38080887LT555510,Ute Geigenmuller, Westborough, USA
DQB1*03:02:01:03295230KY856764,Vera Balz, D,sseldorf, Germany
DQB1*03:26483952_SFCKY800897,Maria Elisa Moraes, Rio de Janeiro, Brazil
DQB1*03:265UA2017tp819LT838343,Mats Bengtsson, Uppsala, Sweden
DQB1*04:01:05ASAN170112_52201936KY658454,Oh-Joong Kwon, Seoul, South Korea
DQB1*04:02:13BY01461KY653742,Carolyn K Hurley, Washington DC, USA
DQB1*05:01:01:04MZ0707821995398,Mehdi Alizadeh, Rennes, Frances
DQB1*05:01:24HGL00600KY563265,Rasmi Thomas, Silver Spring, USA
DQB1*05:03:01:0383327,241799KY856766,Vera Balz, D,sseldorf, Germany
DQB1*05:1488986KY856765,Vera Balz, D,sseldorf, Germany
DQB1*06:02:27281518KY856767,Vera Balz, D,sseldorf, Germany
DQB1*06:02:28121240,280664KY856768,Vera Balz, D,sseldorf, Germany
DQB1*06:09:07BY01468KY653748,Carolyn K Hurley, Washington DC, USA
DRB5*02:02:02087818LT555549,Ute Geigenmuller, Westborough, USA
DPB1*02:01:02:23293657 ,102477,126687,126337,276728,282407,283547KY801329,Vera Balz, D,sseldorf, Germany
DPB1*02:01:02:2468292,74676,292357KY801330,Vera Balz, D,sseldorf, Germany
DPB1*02:01:02:25283955,6074KY801332,Vera Balz, D,sseldorf, Germany
DPB1*02:01:02:26DKMS-LSL-DPB1-1584LT718922,DKMS Life Sciences Lab, Dresden, Germany
DPB1*02:01:02:27DKMS-LSL-DPB1-1582LT718920,DKMS Life Sciences Lab, Dresden, Germany
DPB1*02:01:02:28DKMS-LSL-DPB1-1583LT718921,DKMS Life Sciences Lab, Dresden, Germany
DPB1*02:01:2062090KY801333,Vera Balz, D,sseldorf, Germany
DPB1*04:01:01:12DKMS-LSL-DPB1-1605LT718943,DKMS Life Sciences Lab, Dresden, Germany
DPB1*04:01:01:13DKMS-LSL-DPB1-1607LT718945,DKMS Life Sciences Lab, Dresden, Germany
DPB1*04:01:01:14DKMS-LSL-DPB1-1606LT718944,DKMS Life Sciences Lab, Dresden, Germany
DPB1*04:01:01:15DKMS-LSL-DPB1-1601LT718939,DKMS Life Sciences Lab, Dresden, Germany
DPB1*04:01:01:16DKMS-LSL-DPB1-1600LT718938,DKMS Life Sciences Lab, Dresden, Germany
DPB1*04:01:01:17DKMS-LSL-DPB1-1602LT718940,DKMS Life Sciences Lab, Dresden, Germany
DPB1*04:01:01:18286773,295516,299754,4431,8200,10621,10769,13117,30934,47491KY793541,Vera Balz, D,sseldorf, Germany
DPB1*04:01:01:19286414KY793542,Vera Balz, D,sseldorf, Germany
DPB1*04:01:01:2088081,282145KY793543,Vera Balz, D,sseldorf, Germany
DPB1*04:01:01:21109154,289111KY793544,Vera Balz, D,sseldorf, Germany
DPB1*04:01:01:22292380,281897KY793546,Vera Balz, D,sseldorf, Germany
DPB1*04:01:01:23293029KY793547,Vera Balz, D,sseldorf, Germany
DPB1*04:01:01:24N76685KY793548,Vera Balz, D,sseldorf, Germany
DPB1*04:01:01:25280475KY793545,Vera Balz, D,sseldorf, Germany
DPB1*04:01:04:02DKMS-LSL-DPB1-1608LT718946,DKMS Life Sciences Lab, Dresden, Germany
DPB1*04:01:33286474KY793549,Vera Balz, D,sseldorf, Germany
DPB1*04:02:01:09DKMS-LSL-DPB1-1609LT718947,DKMS Life Sciences Lab, Dresden, Germany
DPB1*04:02:1024187KY793550,Vera Balz, D,sseldorf, Germany
DPB1*06:01:01:03DKMS-LSL-DPB1-1619LT718957,DKMS Life Sciences Lab, Dresden, Germany
DPB1*06:01:04DKMS-LSL-DPB1-1618LT718956,DKMS Life Sciences Lab, Dresden, Germany
DPB1*39:01:02DKMS-LSL-DPB1-1668LT719001,DKMS Life Sciences Lab, Dresden, Germany
DPB1*49:01:01:03DKMS-LSL-DPB1-1573LT718911,DKMS Life Sciences Lab, Dresden, Germany
DPB1*105:01:01:04DKMS-LSL-DPB1-1630LT718968,DKMS Life Sciences Lab, Dresden, Germany
DPB1*124:01:01:02DKMS-LSL-DPB1-1632LT718970,DKMS Life Sciences Lab, Dresden, Germany
DPB1*162:01:02UA2015tp3400LT70773,Mats Bengtsson, Uppsala, Sweden
DPB1*649:01DKMS-LSL-DPB1-1631LT718969,DKMS Life Sciences Lab, Dresden, Germany
DPB1*650:01DKMS-LSL-DPB1-1621LT718959,DKMS Life Sciences Lab, Dresden, Germany
DPB1*651:01109297KY856757,Vera Balz, D,sseldorf, Germany
DPB1*652:01282474,282927KY856759,Vera Balz, D,sseldorf, Germany
DPB1*653:01289118KY856758,Vera Balz, D,sseldorf, Germany

Table 2: Confirmatory Sequences

Sequence Cell identification Accession number Submitting author
A*02:18JM35,LC257688,Takashi Shiina, Isehara, Japan
A*02:621393489,LT838275,Edward KL Yang, Hualien, Taiwan
A*02:653IME 592-16,KY703437,Mariarosa Battarra, Roma, Italy
A*03:204160707058,KY883673,Talitha de Hoop, Utrecht, The Netherlands
A*11:256Q377092,LN835249,Edward KL Yang, Hualien, Taiwan
A*24:584160926035,KY883674,Talitha de Hoop, Utrecht, The Netherlands
A*29:02:20016221117,015939065,LT838207,LT838208,Sarah Colom, La Tronche, France
A*29:10:014140312112,KY883675,Talitha de Hoop, Utrecht, The Netherlands
A*32:60NT01405,KX453669,Carolyn K Hurley, Washington DC, USA
B*13:01:01:01T061,LC257697,Takashi Shiina, Isehara, Japan
B*27:702009tp3623,LT838194,Mats Bengtsson, Uppsala, Sweden
B*27:112406114,LT623896,Edward KL Yang, Hualien, Taiwan
B*35:285160706186,KY883676,Talitha de Hoop, Utrecht, The Netherlands
B*39:04T253,LC257722,Takashi Shiina, Isehara, Japan
B*39:23JM39,LC257723,Takashi Shiina, Isehara, Japan
B*40:50JM34,LC257729,Takashi Shiina, Isehara, Japan
B*40:35323470,KY419487,Vera Balz, D,sseldorf, Germany
C*01:127016215486,LT838224,Sarah Colom, La Tronche, France
DRB1*04:05:01:01JM06,LC257778,Takashi Shiina, Isehara, Japan
DRB1*04:06:01JM43,LC257781,Takashi Shiina, Isehara, Japan
DRB1*04:10:03T253,LC257783,Takashi Shiina, Isehara, Japan
DRB1*08:02:01:01JM18,LC257785,Takashi Shiina, Isehara, Japan
DRB1*08:09JM27,LC257788,Takashi Shiina, Isehara, Japan
DRB1*09:01:02:01JM30,LC257789,Takashi Shiina, Isehara, Japan
DRB1*12:02:01:01KB62UK,LC218001,Uma Kanga, New Delhi, India
DRB1*14:04:01KB100UK,LC217998,Uma Kanga, New Delhi, India
DRB1*15:11D156038,LT837799,Edward KL Yang, Hualien, Taiwan
DPB1*02:01:02:12287826,KY801331,Vera Balz, D,sseldorf, Germany
DPB1*131:01DKMS-LSL-DPB1-1639,LT718974,DKMS Life Sciences Lab, Dresden, Germany
DPB1*519:01 Peripheral Blood,KY697988,Xiaodong Mo, Shenzhen, China

Table 3: Recently Published Sequences

Sequence References


  1. Marsh SGE, Albert ED, Bodmer WF, et al. Nomenclature for factors of the HLA system, 2010. Tissue Antigens 2010 75: 291-455.
  2. Robinson J, Halliwell JA, Hayhurst JD, Flicek P, Parham P, Marsh SGE. The IPD and IMGT/HLA database: allele variant databases. Nucleic Acids Res 2015: 43: 423-31.
  3. Yang KL, Lin PY.Identification of a novel HLA-A*02:01:01 variant, HLA-A*02:01:01:09, in a Taiwanese bone marrow. HLA 2017 89: 301-302.
  4. Yang KL, Ng J, Lazaro A, et al.HLA-A*11:256Q, a novel HLA-A*11 variant, detected in a Taiwanese individual. HLA 2017 89: 302-304.
  5. Gao SQ, Xu YP, He LM, et al.The full length genomic sequence of a novel HLA-A*24 allele, HLA-A*24:353, identified in a patient with hepatitis B infection. HLA 2017 89: 304-305.
  6. Li Z, Zou HY.Full-length sequences of 3 HLA-B alleles, B*07:05:01:01, B*14:01:01 and B*18:02, confirmed by cloning and sequencing. HLA 2017 89: 305-308.
  7. Li Z, Zou HY.Full-length sequences of 4 HLA-B*15 alleles, B*15:03:01:01, B*15:13:01, B*15:18:01:01: and B*15:25:01, confirmed by cloning and sequencing. HLA 2017 89: 309-312.
  8. Li Z, Zou HY.Full-length sequences of 4 HLA-B*15 alleles, B*15:07:01:01, B*15:27:01, B*15:32:01 and B*15:58, confirmed by cloning and sequencing. HLA 2017 89: 313-317.
  9. Li Z, Zou HY.Full-length sequences of four HLA-B*35 alleles, B*35:02:01:01, B*35:03:01:01, B*35:05:01:01 and B*35:08:01:01, confirmed by cloning and sequencing. HLA 2017 89: 317-321.
  10. Li Z, Zou HY.Full-length sequence of 3 HLA-B alleles, HLA-B*40:01:01, B*40:03 and B*40:40 confirmed by cloning and sequencing. HLA 2017 89: 321-324.
  11. Li Z, Zou HY.Full-length sequences of HLA-B*67:01:01 and B*67:01:02, confirmed by cloning and sequencing. HLA 2017 89: 324-327.
  12. Wang SX, Xu YP.A novel HLA-E allele, HLA-E*01:01:01:07, identified in a Chinese Leukemia patient. HLA 2017 89: 327-330.