HLA Alleles Numbers

Assigned as of December 2022

The numbers below represent the number of named alleles for each gene. This number includes alleles that have been named but whose sequences are still confidential. This means that the number of sequences found in some files on this site may differ from the number of sequences indicated in this table. Details of the alleles that are still confidential can be seen in the latest version reports on the IPD-IMGT/HLA Database web site. The numbers below do not include the names of any deleted alleles - further details of deleted alleles can be found here. If you wish to cite these numbers in a publication, please see our citations page for further details.


Numbers of HLA Alleles
HLA Class I Alleles 25,228
HLA Class II Alleles 10,592
HLA Alleles 35,821
Other non-HLA Alleles 798
Number of Confidential Alleles 0
HLA Class I
Gene A B C E F G
Alleles 7,712 9,164 7,672 346 59 117
Proteins 4,496 5,511 4,265 140 11 38
Nulls 399 322 334 10 0 6
HLA Class I - Pseudogenes
Gene H J K L N P S T U V W Y
Alleles 67 33 6 5 5 5 7 8 5 3 11 3
Proteins 0 0 0 0 0 0 0 0 0 0 0 0
Nulls 0 0 0 0 0 0 0 0 0 0 0 0
HLA Class II
Gene DRA DRB DQA1 DQA2 DQB1 DQB2 DPA1 DPA2 DPB1 DPB2 DMA DMB DOA DOB
Alleles 46 4,374 556 40 2,419 35 531 5 2,229 6 58 71 92 60
Proteins 5 2,871 267 11 1,490 8 248 0 1,342 0 9 9 14 15
Nulls 0 189 13 0 109 0 22 0 117 0 0 0 1 0
HLA Class II - DRB Alleles
Gene DRB1 DRB2 DRB3 DRB4 DRB5 DRB6 DRB7 DRB8 DRB9
Alleles 3,486 1 456 230 189 3 2 1 6
Proteins 2,240 0 341 146 144 0 0 0 0
Nulls 117 0 23 26 23 0 0 0 0
Other non-HLA Genes
Gene HFE MICA MICB TAP1 TAP2
Alleles 6 531 244 12 12
Proteins 4 280 47 6 5
Nulls 0 8 25 1 0