Nomenclature for Factors of the HLA System

March 2013

Compiled by Steven G. E. Marsh for the WHO Nomenclature Committee for Factors of the HLA System.

Published In:

The following sequences have been submitted to the Nomenclature Committee since the February 2013 nomenclature update and, following agreed policy, have been assigned official allele designations. Full details of all sequences will be published in a forthcoming report.

Below are listed the newly assigned sequences (Table 1) and confirmations of previously reported sequences (Table 2). The accession number of each sequence is given and these can be used to retrieve the sequence files from the EMBL, GenBank or DDBJ data libraries. Although accession numbers have been assigned by the data-libraries and most sequences are already available, there is still the possibility that an author may not yet have allowed the sequence to be released; in such a case you will have to contact the submitting author directly. Additional information pertaining to new sequences is often included in the publications describing these alleles; a listing of recent publications that describe new HLA sequences is given in Table 3. The sequence known as MICA*071 has been shown to be identical to the MICA*017 allele, consequently the designation MICA*071 has been abandoned.

All new and confirmatory sequences should now be submitted directly to the WHO Nomenclature Committee for Factors of the HLA System via the IMGT/HLA Database using the sequence submission tool provided (2). The IMGT/HLA Database may be accessed via the world wide web at : http://ww.ebi.ac.uk/imgt/hla/.

Table 1: New Sequences


Sequence Cell identification Accession number Submitting author
A*01:01:54HG00005330KC185428Histogenetics, Ossining, USA
A*01:01:55HG00005331KC185427Histogenetics, Ossining, USA
A*01:01:56HG00005333KC185426Histogenetics, Ossining, USA
A*01:129HG00005332HM562285Histogenetics, Ossining, USA
A*01:1304670903182KC701038Xin Li, Harbin, China
A*02:413HG00005338KC300249Histogenetics, Ossining, USA
A*02:414HG00005340HM125808Histogenetics, Ossining, USA
A*02:415F4817KC686716Keming Du, Shanghai, China
A*02:4164520900460KC736065Xin Li, Harbin, China
A*02:41724037DalianKC590326Yu Weijian, DaLian, China
A*03:01:404551200075KC736066Xin Li, Harbin, China
A*03:164HG00005334KC155580Histogenetics, Ossining, USA
A*03:165HG00005335KC253907Histogenetics, Ossining, USA
A*03:166HG00005336KC185423Histogenetics, Ossining, USA
A*11:01:477311212286KC683822Jia Luo, Changsha, China
A*11:1427311114750KC683821Jia Luo, Changsha, China
A*24:232N48646KC590323Yu Weijian, DaLian, China
A*26:8596072770KC788281Daniel Fuerst, Ulm, Germany
A*29:53HG00005326HM004295Histogenetics, Ossining, USA
A*30:73N96060950KC521473Daniel Fuerst, Ulm, Germany
A*30:744531100053KC701037Xin Li, Harbin, China
A*31:01:18HG00005327KC209747Histogenetics, Ossining, USA
A*31:745341100624KC166288Cuiyun Zhao, Jinan, China
A*33:68HG00005328KC253906Histogenetics, Ossining, USA
A*68:01:19HG00005329KC155586Histogenetics, Ossining, USA
B*07:186HG00005348KC348376Histogenetics, Ossining, USA
B*07:187HG00005362KC136251Histogenetics, Ossining, USA
B*07:188HG00005363KC185436Histogenetics, Ossining, USA
B*07:189HG00005364KC209762Histogenetics, Ossining, USA
B*07:190HG00005365KC209751Histogenetics, Ossining, USA
B*08:107HG00005347HQ590408Histogenetics, Ossining, USA
B*08:108CTM-3017319KC632522Antonio Balas, Madrid, Spain
B*13:65HG00005349KC185430Histogenetics, Ossining, USA
B*13:66HG00005361KC209754Histogenetics, Ossining, USA
B*13:6746996KC590322Yu Weijian, DaLian, China
B*15:272NHG00005356KC300251Histogenetics, Ossining, USA
B*15:273HG00005357KC209763Histogenetics, Ossining, USA
B*15:274HG00005359KC136250Histogenetics, Ossining, USA
B*15:2754511102455KC701035Xin Li, Harbin, China
B*18:87HG00005226JX976738Histogenetics, Ossining, USA
B*18:88HG00005345KC209753Histogenetics, Ossining, USA
B*18:89HG00005346KC209757Histogenetics, Ossining, USA
B*27:104HG00005344KC185435Histogenetics, Ossining, USA
B*27:1055751200634KC679053Faming Zhu, Hangzhou, China
B*35:228HG00005354KC209755Histogenetics, Ossining, USA
B*35:229HG00005355KC185433Histogenetics, Ossining, USA
B*35:2304510903829KC701034Xin Li, Harbin, China
B*38:02:057311212839KC683819Jia Luo, Changsha, China
B*40:01:30F6028KC686718Keming Du, Shanghai, China
B*40:234HG00005341KC253915Histogenetics, Ossining, USA
B*40:235HG00005343KC209759Histogenetics, Ossining, USA
B*40:2367311212807KC683820Jia Luo, Changsha, China
B*40:2377311212396KC683823Jia Luo, Changsha, China
B*40:238GD7024KC776574Chen-Chung Chu, New Taipei City, Taiwan
B*41:02:05HG00005342KC209758Histogenetics, Ossining, USA
B*44:02:28HG00005352KC155589Histogenetics, Ossining, USA
B*44:02:29HG00005353KC300252Histogenetics, Ossining, USA
B*44:175HG00005351KC253922Histogenetics, Ossining, USA
B*51:152HG00005360KC185437Histogenetics, Ossining, USA
B*53:30HG00005358KC209760Histogenetics, Ossining, USA
C*03:04:3629441340JX971229Oh-Joong Kwon, Seoul, South Korea
C*06:9971014276KC788179Oh-Joong Kwon, Seoul, South Korea
C*07:307MDA0000075KC677669Kai Cao, Houston, USA
DRB1*01:01:26HG00005323JX842731Histogenetics, Ossining, USA
DRB1*12:01:0543235KC590325Yu Weijian, DaLian, China
DRB1*13:1614671100269KC701039Xin Li, Harbin, China
DRB1*14:01:04HG00004758JX458906Histogenetics, Ossining, USA
DRB1*16:2340428KC590324Yu Weijian, DaLian, China
DQA1*04:01:02:02215677HE980021Klaus Witter, M�nchen, Germany
DQB1*02:27ERL17614HE978782Juergen Zingsem, Erlangen, Germany
DQB1*02:28HG00005564JX992577Histogenetics, Ossining, USA
DQB1*02:29HG00005566,
HG00005567,
HG00005568		KC019972,
KC185453,
KC300270		Histogenetics, Ossining, USA
DQB1*03:17:02HF912275HF912275Rafael Formenton Cita, Barretos, Brazil
DQB1*03:71HG00005565JX992588Histogenetics, Ossining, USA
DQB1*03:72HG00005571JX667742Histogenetics, Ossining, USA
DQB1*04:02:03HG00005572,
HG00005573,
HG00005574,
HG00005575,
HG00005576		JX992602,
JX992593,
KC253935,
JX976760,
KC019973		Histogenetics, Ossining, USA
DQB1*04:11HG00005570JX992599Histogenetics, Ossining, USA
DQB1*04:12HG00005577JX992597Histogenetics, Ossining, USA
DQB1*05:01:08HG00005555KC209772Histogenetics, Ossining, USA
DQB1*05:02:04HG00005556JX992613Histogenetics, Ossining, USA
DQB1*05:03:06HG00005557KC019996Histogenetics, Ossining, USA
DQB1*05:03:07HG00005558JX667735Histogenetics, Ossining, USA
DQB1*05:23HG00005559,
HG00005560		KC019962,
JX992622		Histogenetics, Ossining, USA
DQB1*05:24HG00005561KC020004Histogenetics, Ossining, USA
DQB1*05:25HG00005562KC253934Histogenetics, Ossining, USA
DQB1*05:26HG00005563JX992591Histogenetics, Ossining, USA
DQB1*06:02:03HG00005582KC020003Histogenetics, Ossining, USA
DQB1*06:02:04HG00005592JX842724Histogenetics, Ossining, USA
DQB1*06:02:05HG00005602KC019985Histogenetics, Ossining, USA
DQB1*06:02:06HG00005607KC020013Histogenetics, Ossining, USA
DQB1*06:13:02HG00005601KC185451Histogenetics, Ossining, USA
DQB1*06:15:02HG00005589KC253936Histogenetics, Ossining, USA
DQB1*06:22:02HG00005579,
HG00005580		KC136263,
JX842722		Histogenetics, Ossining, USA
DQB1*06:68HG00005569KC020000Histogenetics, Ossining, USA
DQB1*06:69HG00005578KC185450Histogenetics, Ossining, USA
DQB1*06:70HG00005581KC019999Histogenetics, Ossining, USA
DQB1*06:71HG00005583KC185452Histogenetics, Ossining, USA
DQB1*06:72HG00005591KC300274Histogenetics, Ossining, USA
DQB1*06:73HG00005593JX970504Histogenetics, Ossining, USA
DQB1*06:74HG00005594,
HG00005595		JX524821,
JX976757		Histogenetics, Ossining, USA
DQB1*06:75NHG00005596,
HG00005597		KC348386,
KC253923		Histogenetics, Ossining, USA
DQB1*06:76HG00005598KC300268Histogenetics, Ossining, USA
DQB1*06:77NHG00005599KC019951Histogenetics, Ossining, USA
DQB1*06:78HG00005600JX992580Histogenetics, Ossining, USA
DQB1*06:79HG00005603,
HG00005604,
HG00005605,
HG00005719		KC019981,
KC300269,
KC019961,
KC300267		Histogenetics, Ossining, USA
DQB1*06:80HG00005606KC019991Histogenetics, Ossining, USA
DQB1*06:81HG00005608,
HG00005609,
HG00005610,
HG00005611,
HG00005612,
HG00005613,
HG00005720		JX992623,
JX992626,
KC020017,
KC020018,
KC019954,
KC136254,
JX992592		Histogenetics, Ossining, USA
DQB1*06:82HG00005614KC300272Histogenetics, Ossining, USA
DQB1*06:83HG00005615KC019963Histogenetics, Ossining, USA
DQB1*06:84Ua2013tp753HF912274Mats Bengtsson, Uppsala, Sweden
DPB1*02:01:09HG00005643JX482015Histogenetics, Ossining, USA
DPB1*03:01:03HG00005654JX482012Histogenetics, Ossining, USA
DPB1*04:01:04HG00005626,
HG00005627,
HG00005628,
HG00005629,
HG00005630,
HG00005631		JX482007,
JX482008,
JX482009,
JX482011,
JX482013,
KC020019		Histogenetics, Ossining, USA
DPB1*04:01:05HG00005633KC300278Histogenetics, Ossining, USA
DPB1*04:01:06HG00005637KC300277Histogenetics, Ossining, USA
DPB1*04:01:07HG00005638JX866723Histogenetics, Ossining, USA
DPB1*143:01HG00005623JX842729Histogenetics, Ossining, USA
DPB1*144:01HG00005624JX482014Histogenetics, Ossining, USA
DPB1*145:01HG00005625JX667746Histogenetics, Ossining, USA
DPB1*146:01HG00005632JX667747Histogenetics, Ossining, USA
DPB1*147:01HG00005634KC155595Histogenetics, Ossining, USA
DPB1*148:01HG00005635JX992572Histogenetics, Ossining, USA
DPB1*149:01HG00005636KC209781Histogenetics, Ossining, USA
DPB1*150:01HG00005639KC209779Histogenetics, Ossining, USA
DPB1*151:01HG00005640KC209780Histogenetics, Ossining, USA
DPB1*152:01HG00005641JX482006Histogenetics, Ossining, USA
DPB1*153:01HG00005642JX992570Histogenetics, Ossining, USA
DPB1*154:01NHG00005644JX482017Histogenetics, Ossining, USA
DPB1*155:01HG00005645JX842730Histogenetics, Ossining, USA
DPB1*156:01HG00005648KC253938Histogenetics, Ossining, USA
DPB1*157:01HG00005649JX482010Histogenetics, Ossining, USA
DPB1*158:01HG00005650JX992573Histogenetics, Ossining, USA
DPB1*159:01NHG00005651KC155594Histogenetics, Ossining, USA
DPB1*160:01HG00005653JX992571Histogenetics, Ossining, USA
DPB1*161:01NHG00005655JX667745Histogenetics, Ossining, USA

Table 2: Confirmatory Sequences


Sequence Cell identification Accession number Submitting author
A*01:113HG00005656KC348375Histogenetics, Ossining, USA
A*02:20:01MDA0000080KC692342Kai Cao, Houston, USA
A*02:407F5978KC686717Keming Du, Shanghai, China
A*02:40:02HG00005339KC253908Histogenetics, Ossining, USA
A*24:02:35HG00005662JN123995Histogenetics, Ossining, USA
A*24:184HG00005663JX667716Histogenetics, Ossining, USA
A*26:01:19HG00005658,
HG00005659,
HG00005660		JX667712,
JX667713,
JX667714		Histogenetics, Ossining, USA
A*29:21HG00005657JQ964634Histogenetics, Ossining, USA
A*30:36HG00005661HM594760Histogenetics, Ossining, USA
B*08:12:01MDA0000092KC702246Kai Cao, Houston, USA
B*13:50HG00005350HM562309Histogenetics, Ossining, USA
B*15:04MDA0000072,
MDA0000073		KC677666,
KC677667		Kai Cao, Houston, USA
B*15:05:01MDA0000074KC677668Kai Cao, Houston, USA
B*15:07:01MDA0000076KC692338Kai Cao, Houston, USA
B*15:09MDA0000077KC692339Kai Cao, Houston, USA
B*15:12MDA0000078KC692340Kai Cao, Houston, USA
B*15:15MDA0000079KC692341Kai Cao, Houston, USA
B*15:21MDA0000081KC692343Kai Cao, Houston, USA
B*15:27:01 MDA0000082,
MDA0000083		KC692344,
KC692345		Kai Cao, Houston, USA
B*15:46MDA0000084KC692346Kai Cao, Houston, USA
B*15:47:01MDA0000085KC702239Kai Cao, Houston, USA
B*15:48MDA0000086KC702240Kai Cao, Houston, USA
B*18:08 MDA0000107,
MDA0000108		KC789819,
KC789820		Kai Cao, Houston, USA
B*27:07:01MDA0000087KC702241Kai Cao, Houston, USA
B*27:12 MDA0000088,
MDA0000089		KC702242,
KC702243		Kai Cao, Houston, USA
B*27:14 MDA0000090,
MDA0000091		KC702244,
KC702245		Kai Cao, Houston, USA
B*35:10MDA0000093KC776217Kai Cao, Houston, USA
B*35:11:01MDA0000094KC776218Kai Cao, Houston, USA
B*35:16MDA0000095KC776219Kai Cao, Houston, USA
B*35:24:01MDA0000096KC776220Kai Cao, Houston, USA
B*35:41MDA0000097KC776221Kai Cao, Houston, USA
B*40:03MDA0000105KC789817Kai Cao, Houston, USA
B*40:08MDA0000098KC776222Kai Cao, Houston, USA
B*40:64MDA0000099KC776223Kai Cao, Houston, USA
B*41:03:01MDA0000100KC776224Kai Cao, Houston, USA
B*42:02MDA0000101KC776225Kai Cao, Houston, USA
B*51:07:01MDA0000102KC776226Kai Cao, Houston, USA
B*51:14MDA0000103KC789815Kai Cao, Houston, USA
B*56:04MDA0000104KC789816Kai Cao, Houston, USA
B*59:01:01:01MDA0000106KC789818Kai Cao, Houston, USA
C*01:5811221356KC788283Daniel Fuerst, Ulm, Germany
DQA1*04:02218235HF674388Klaus Witter, M�nchen, Germany
DQB1*03:63218686HF912155Klaus Witter, M�nchen, Germany
DQB1*05:01:0512G20JX498912Arturas Jakubauskas, Vilnius, Lithuania
DQB1*06:48HG00005584,
HG00005585,
HG00005586,
HG00005587,
HG00005588		JX524822,
KC209770,
KC020006,
KC253933,
JX667740		Histogenetics, Ossining, USA
DQB1*06:49HG00005721,
HG00005722,
HG00005616,
HG00005617,
HG00005618,
HG00005619,
HG00005620,
HG00005621,
HG00005622		JX992583,
JX992596,
JX992601,
JX992625,
KC020011,
KC209773,
KC020002,
JX992624,
JX992589		Histogenetics, Ossining, USA
DQB1*06:50HG00005590KC019958Histogenetics, Ossining, USA
DPB1*09:01:02HG00005646,
HG00005647		KC253937,
KC300276		Histogenetics, Ossining, USA
MICA*017SZGSQ-14JQ619159Su-Qing Gao, Shenzhen, China

Table 3: Recently Published Sequences


Sequence References
A*02:023
A*25:01:013
A*36:013
A*68:03:013
A*74:013
B*15:01:013
B*15:16:013
B*39:06:023
B*44:02:274
B*46:295
B*55:346
B*57:03:013
B*81:013
C*02:103
C*03:053
C*04:09N3
C*08:04:013
C*16:02:013
DRB1*03:807
DRB1*11:1298
DRB1*14:1299
DRB1*14:13610
DPA1*02:02:0511
MICA*06912

References:

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