Nomenclature for Factors of the HLA System

March 2012

Compiled by Steven G. E. Marsh for the WHO Nomenclature Committee for Factors of the HLA System.

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The following sequences have been submitted to the Nomenclature Committee since the Mayblank.html 2011 nomenclature update and, following agreed policy, have been assigned official allele designations. Full details of all sequences will be published in a forthcoming report.

Below are listed the newly assigned sequences (Table 1) and confirmations of previously reported sequences (Table 2). The accession number of each sequence is given and these can be used to retrieve the sequence files from the EMBL, GenBank or DDBJ data libraries. Although accession numbers have been assigned by the data-libraries and most sequences are already available, there is still the possibility that an author may not yet have allowed the sequence to be released; in such a case you will have to contact the submitting author directly. Additional information pertaining to new sequences is often included in the publications describing these alleles; a listing of recent publications that describe new HLA sequences is given in Table 3. The sequence DRB1*03:11:02 has been shown to be in error and the name has been abandoned.

All new and confirmatory sequences should now be submitted directly to the WHO Nomenclature Committee for Factors of the HLA System via the IMGT/HLA Database using the sequence submission tool provided (2). The IMGT/HLA Database may be accessed via the world wide web at :

Table 1: New Sequences

Sequence Cell identification Accession number Submitting author
A*01:10891954223HE680088Dominique Masson, La Tronche, France
A*01:109FRFGR17845HE680089Dominique Masson, La Tronche, France
A*02:3577311120097JQ765600Min Dai, Yueyang, China
A*02:3587311120607JQ765601Min Dai, Yueyang, China
JQ712685Manuela Testi, Rome, Italy
A*11:121BY00916JQ670869Carolyn K Hurley, Washington DC, USA
A*11:1227311121360JQ765602Min Dai, Yueyang, China
A*30:63BY00915JQ670868Carolyn K Hurley, Washington DC, USA
A*31:01:13CHA11-295JQ743704Ji Young Huh, Sungnam-si, South Korea
A*32:01:1396004951JQ712688Daniel Fuerst, Ulm, Germany
A*32:417311123005JQ765603Min Dai, Yueyang, China
A*33:59BY00917JQ670870Carolyn K Hurley, Washington DC, USA
B*18:71101516916HE680091Dominique Masson, La Tronche, France
B*35:05:0311-72-2013HE650143Wendy Swelsen, Amsterdam, The Netherlands
B*35:199HG00002424HQ879826Histogenetics, Ossining, USA
B*35:200BY00918JQ670871Carolyn K Hurley, Washington DC, USA
B*39:39:02HG00003104JN604859Histogenetics, Ossining, USA
B*44:15191152437HE680090Dominique Masson, La Tronche, France
B*44:152CTM-1012888JQ739211Antonio Balas, Madrid, Spain
B*52:2910-72-3977HE664021Wendy Swelsen, Amsterdam, The Netherlands
B*57:01:1311-93-0008HE664022Wendy Swelsen, Amsterdam, The Netherlands
C*03:146ANCB739361ANHE687290Steven GE Marsh, London, United Kingdom
C*06:76CABO041243ANHE687291Steven GE Marsh, London, United Kingdom
C*12:02:09HG00003183JN124421Histogenetics, Ossining, USA
C*12:18:02HG00003180JN124415Histogenetics, Ossining, USA
C*12:73HG00003179JN124433Histogenetics, Ossining, USA
C*12:74HG00003181JN124387Histogenetics, Ossining, USA
C*12:75HG00003187JN418830Histogenetics, Ossining, USA
C*12:76FRFLY19654HE680092Dominique Masson, La Tronche, France
C*14:3790165693JQ712686Daniel Fuerst, Ulm, Germany
C*15:02:09HG00003192JN124392Histogenetics, Ossining, USA
C*15:02:10HG00003194JN124413Histogenetics, Ossining, USA
C*15:58HG00003189JN124429Histogenetics, Ossining, USA
C*15:59HG00003191JN124402Histogenetics, Ossining, USA
C*15:60HG00003193JN124440Histogenetics, Ossining, USA
E*01:03:05TMO1158JQ744563Erick Castelli, Ribeirao Preto, Sao Paulo, Brazil
DRB1*03:81BY00543GU066754Carolyn K Hurley, Washington DC, USA
DRB1*09:01:08345638HE663455Edward KL Yang, Hualien, Taiwan
DRB1*13:139RAFJeanHE681415Sylvie Tourne, Strasbourg, France
DQB1*03:40MDA0000001JQ694164Kai Cao, Houston, USA
DQB1*06:49DNA20110145HE774674Harald Schulze, Berlin, Germany
DPB1*138:01Rome778/11JQ686672Manuela Testi, Rome, Italy
DPB1*139:017550800968JQ740763Yunping Xu, Shenzhen, China

Table 2: Confirmatory Sequences

Sequence Cell identification Accession number Submitting author
A*02:02Sep-67JQ771778Dimitri Monos, Philadelphia, USA
A*02:180HG00003569JQ007621Histogenetics, Ossining, USA
A*02:206HG00003574JQ007602Histogenetics, Ossining, USA
Histogenetics, Ossining, USA
A*03:97HG00003542JN124168Histogenetics, Ossining, USA
A*23:19QMDA0000002JQ793890Kai Cao, Houston, USA
A*24:02:27HG00003521JQ085351Histogenetics, Ossining, USA
A*24:129HG00003506JN124123Histogenetics, Ossining, USA
A*25:01:0108-1621JQ771871Dimitri Monos, Philadelphia, USA
A*26:01:15HG00003487JQ031220Histogenetics, Ossining, USA
A*26:42HG00003493JN182954Histogenetics, Ossining, USA
A*30:42HG00003502JQ031216Histogenetics, Ossining, USA
A*36:01Sep-29JQ771779Dimitri Monos, Philadelphia, USA
A*68:03:01Sep-11JQ771782Dimitri Monos, Philadelphia, USA
A*74:01Sep-11JQ771780Dimitri Monos, Philadelphia, USA
B*07:110HG00003764JQ007652Histogenetics, Ossining, USA
B*08:53HG00003661JN561733Histogenetics, Ossining, USA
B*15:10:01Aug-48JQ771783Dimitri Monos, Philadelphia, USA
B*15:16:01Sep-64JQ771784Dimitri Monos, Philadelphia, USA
B*18:50HG00003648JQ048689Histogenetics, Ossining, USA
B*35:24:02HG00003682JQ007636Histogenetics, Ossining, USA
B*35:149HG00003705JN123795Histogenetics, Ossining, USA
B*38:37HG00003774JN124215Histogenetics, Ossining, USA
B*39:06:02Sep-04JQ771785Dimitri Monos, Philadelphia, USA
B*39:0760682163JQ683080Antonio Balas, Madrid, Spain
B*39:68HG00003771JN124220Histogenetics, Ossining, USA
B*40:119BY00919JQ670872Carolyn K Hurley, Washington DC, USA
B*41:10HG00003619JN123820Histogenetics, Ossining, USA
B*41:16HG00003626JN123794Histogenetics, Ossining, USA
B*44:03:08HG00003742JQ085348Histogenetics, Ossining, USA
B*44:03:11HG00003613JN119402Histogenetics, Ossining, USA
B*44:55342418HE687289Edward KL Yang, Hualien, Taiwan
B*51:01:3312203200JQ712687Daniel Fuerst, Ulm, Germany
B*56:01:03HG00003721JN119393Histogenetics, Ossining, USA
B*57:03:01Sep-64JQ771786Dimitri Monos, Philadelphia, USA
B*81:01Sep-98JQ771787Dimitri Monos, Philadelphia, USA
B*81:05HG00003763JQ007642Histogenetics, Ossining, USA
C*01:45HG00003864JQ007696Histogenetics, Ossining, USA
C*02:02:11HG00003987JN123889Histogenetics, Ossining, USA
C*02:1006-0678JQ771788Dimitri Monos, Philadelphia, USA
Histogenetics, Ossining, USA
Histogenetics, Ossining, USA
C*02:55HG00003990JN406477Histogenetics, Ossining, USA
C*03:04:19HG00004005JN675288Histogenetics, Ossining, USA
C*03:05Sep-61JQ771789Dimitri Monos, Philadelphia, USA
C*03:55HG00004001JN124504Histogenetics, Ossining, USA
C*03:81HG00003998JN124465Histogenetics, Ossining, USA
C*04:09NOct-40JQ771790Dimitri Monos, Philadelphia, USA
C*04:42HG00003925JN119443Histogenetics, Ossining, USA
C*04:46HG00003850JN182987Histogenetics, Ossining, USA
C*05:42HG00003821JN124434Histogenetics, Ossining, USA
C*06:32HG00003796JN242443Histogenetics, Ossining, USA
C*06:37HG00003881JN124554Histogenetics, Ossining, USA
C*06:38HG00003792JQ085357Histogenetics, Ossining, USA
C*07:102HG00003929JN119468Histogenetics, Ossining, USA
C*07:116HG00003897JQ048680Histogenetics, Ossining, USA
Histogenetics, Ossining, USA
C*08:04:0106-0678JQ771791Dimitri Monos, Philadelphia, USA
C*08:37HG00003867JN119455Histogenetics, Ossining, USA
C*12:03:12HG00003940JN123894Histogenetics, Ossining, USA
C*12:38HG00003952JN123918Histogenetics, Ossining, USA
Histogenetics, Ossining, USA
C*16:02:0108-1552JQ771792Dimitri Monos, Philadelphia, USA
C*16:07:02HG00003824JQ031248Histogenetics, Ossining, USA
Histogenetics, Ossining, USA
Histogenetics, Ossining, USA
DRB1*13:97HG00004068JN119529Histogenetics, Ossining, USA
DRB1*15:68HG00004040JN119508Histogenetics, Ossining, USA

Table 3: Recently Published Sequences

Sequence References


  1. Marsh SGE, Albert ED, Bodmer WF, et al. Nomenclature for Factors of the HLA system, 2010. Tissue Antigens. 2010 75:291-455.
  2. Robinson J, Malik A, Parham P, Bodmer JG, Marsh SGE. IMGT/HLA database--a sequence database for the human major histocompatibility complex. Tissue Antigens. 2000. 55: 280-7.
  3. Hong SS, Sung HY, Kang MS, Huh JY. HLA-A*02:328, a novel allele identified by sequence-based typing in cord blood from a Korean woman. Tissue Antigens. 2012. 79: 308.
  4. Swelsen WT, Poell B, Hartog KS, Lardy NM. Characterization of a new allele: HLA-A*03:134. Tissue Antigens. 2012. 79: 309-10.
  5. Barbuti S, Fornaciari S, Mariotti ML, Curcio M, Scatena F. A novel HLA-B*51:01:29 allele identified by sequence-based typing. Tissue Antigens. 2012. 79: 310-1.
  6. Moraru M, Balas A, de Pablo R, Vicario JL, Vilches C. Allele-specific amplification of the complete HLA-C gene from genomic DNA - a novel Cw4 allele (C*04:71) with a Cw1 motif in the peptide-binding site. Tissue Antigens. 2012. 79: 291-4.
  7. Zhang W, Wang W, Zhu FM, Lv HJ, Yan LX. Characterization of a novel allele, HLA-DQB1*05:03:05. Tissue Antigens. 2012. 79: 311-2.
  8. Zhang S, Wang J, Luo M, Li X, Chen Q. A novel allele: MICA*064N with a stop codon in exon 4. Tissue Antigens. 2012. 79: 313-4.