Nomenclature for Factors of the HLA System
November 2009
Compiled by Steven G. E. Marsh for the WHO Nomenclature Committee for Factors of the HLA System.
Published In:
- Tissue Antigens. 2010 76:76-80
- Human Immunology. 2010 71:324-7
- International Journal of Immunogenetics. 2010 37:149-53
The following sequences have been submitted to the Nomenclature Committee since the October 2009 nomenclature update and, following agreed policy, have been assigned official allele designations. Full details of all sequences will be published in a forthcoming report.
Below are listed the newly assigned sequences (Table 1) and confirmations of previously reported sequences (Table 2). The accession number of each sequence is given and these can be used to retrieve the sequence files from the EMBL, GenBank or DDBJ data libraries. Although accession numbers have been assigned by the data-libraries and most sequences are already available, there is still the possibility that an author may not yet have allowed the sequence to be released; in such a case you will have to contact the submitting author directly. Additional information pertaining to new sequences is often included in the publications describing these alleles; a listing of recent publications that describe new HLA sequences is given in Table 3.
All new and confirmatory sequences should now be submitted directly to the WHO Nomenclature Committee for Factors of the HLA System via the IMGT/HLA Database using the sequence submission tool provided. The IMGT/HLA Database may be accessed via the world wide web at : http://ww.ebi.ac.uk/imgt/hla/.
Table 1: New Sequences
| Sequence | Cell identification | Accession number | Submitting author |
|---|---|---|---|
| A*0370 | BY00566 | GU138060 | Carolyn K Hurley, Washington DC, USA |
| A*0371 | HT-59 | GU169071 | Min Yu, Chicago, USA |
| A*260113 | HN-7541 | FJ224228 | Histogenetics, Ossining, USA |
| A*2922 | DEDK698352 | FN582331 | Steven GE Marsh, London, United Kingdom |
| B*070219 | JMDP01K046 | AB512680 | Kenji Tadokoro, Tokyo, Japan |
| B*130103 | K34517 | GU136390 | Marie Lin, Taipei, Taiwan |
| B*350204 | 09218414 | GU191548 | Daniel Fuerst, Ulm, Germany |
| B*5729 | SZGSQ-4 | GU166293 | Su-Qing Gao, Shenzhen, China |
| B*5827 | DL-BK | GU071234 | BingShen Ke, Jinan, China |
| Cw*010209 | HN-67204-1 | FJ875627 | Histogenetics, Ossining, USA |
| Cw*0134 | PBMC-JQZ | GQ365731 | JianQiong Zhang, Nanjing, China |
| Cw*020209 | HN-70709-9, HN-28218-5, HN-97117-5 |
FJ640584, FJ976830, FJ976839 |
Histogenetics, Ossining, USA |
| Cw*020210 | HN-25390-3 | FJ594638 | Histogenetics, Ossining, USA |
| Cw*020211 | HN-66330-9 | FJ765993 | Histogenetics, Ossining, USA |
| Cw*030206 | HN-759098 | FJ792493 | Histogenetics, Ossining, USA |
| Cw*030415 | HN-20607-9 | FJ619432 | Histogenetics, Ossining, USA |
| Cw*030416 | HN-67433-1 | FJ766000 | Histogenetics, Ossining, USA |
| Cw*030417 | HN-60094-6, HN-56321-9, HN-51699-3, HN-51054-1, HN-50983-2 |
FJ765995, FJ875591, FJ875592, FJ875593, FJ875594 |
Histogenetics, Ossining, USA |
| Cw*030418 | HN-718581 | FJ792503 | Histogenetics, Ossining, USA |
| Cw*0377 | HN-75897-9 | FJ765749 | Histogenetics, Ossining, USA |
| Cw*0378 | HN-38248-9 | FJ765876 | Histogenetics, Ossining, USA |
| Cw*0379 | HN-51098-8 | FJ858899 | Histogenetics, Ossining, USA |
| Cw*040113 | HN-27574-4, HN-68911-4, HN-26496-7 |
FJ619434, FJ765994, FJ766001 |
Histogenetics, Ossining, USA |
| Cw*040114 | HN-769287 | FJ792490 | Histogenetics, Ossining, USA |
| Cw*0450 | HN-1252167 | FJ392211 | Histogenetics, Ossining, USA |
| Cw*0451 | HN-9832463 | FJ392221 | Histogenetics, Ossining, USA |
| Cw*0452 | HN-90881-3 | FJ640585 | Histogenetics, Ossining, USA |
| Cw*0453 | HN-0650688 | FJ792488 | Histogenetics, Ossining, USA |
| Cw*0532 | HN-06590-2, HN-74682-6 |
FJ619423, FJ969929 |
Histogenetics, Ossining, USA |
| Cw*0533 | HN-76528-1, HN-87304-0 |
FJ765751, FJ765922 |
Histogenetics, Ossining, USA |
| Cw*0534 | HN-36886-9, HN-75619-4, HN-76641-9 |
FJ392193, FJ875589, FJ969921 |
Histogenetics, Ossining, USA |
| Cw*070212 | HN-8224910 | FJ392227 | Histogenetics, Ossining, USA |
| Cw*070213 | HN-2762021 | FJ792505 | Histogenetics, Ossining, USA |
| Cw*0794 | HN-08894-8 | FJ619431 | Histogenetics, Ossining, USA |
| Cw*0795 | HN-61294-5, HN-86379-4 |
FJ765746, FJ976843 |
Histogenetics, Ossining, USA |
| Cw*0796 | HN-4723-8 | FJ765752 | Histogenetics, Ossining, USA |
| Cw*0797 | HN-16390-1, HN-58064-0 |
FJ765763, FJ875622 |
Histogenetics, Ossining, USA |
| Cw*0798N | HN-12269-0 | FJ875631 | Histogenetics, Ossining, USA |
| Cw*0799 | HN-30334-7 | FJ392209 | Histogenetics, Ossining, USA |
| Cw*0831 | 801P08, 902P08 | FN568089 | Sonia Nesci, Pesaro, Italy |
| Cw*120204 | HN-5264226 | FJ765988 | Histogenetics, Ossining, USA |
| Cw*120309 | HN-98468-9 | FJ765762 | Histogenetics, Ossining, USA |
| Cw*1229 | HN-08004-5 | FJ619436 | Histogenetics, Ossining, USA |
| Cw*1230 | HN-20602-2, HN-40116-2, HN-62540-6 |
FJ619437, FJ976874, FJ976876 |
Histogenetics, Ossining, USA |
| Cw*1231 | HN-23222-7 | FJ765764 | Histogenetics, Ossining, USA |
| Cw*1415 | HN-12308-0 | FJ765923 | Histogenetics, Ossining, USA |
| Cw*150205 | HN-50699-6 | FJ765998 | Histogenetics, Ossining, USA |
| Cw*1524 | HN-30608-6, HN-28600-9 |
FJ765756, FJ976807 |
Histogenetics, Ossining, USA |
| Cw*1525 | G18106156010P | GU133628 | Dimitra Niokou, London, United Kingdom |
| Cw*160104 | HN-751293, HN-4604700 |
FJ792491, FJ792511 |
Histogenetics, Ossining, USA |
| Cw*160202 | HN-758777 | FJ792492 | Histogenetics, Ossining, USA |
| Cw*1618 | HN-44614-8 | FJ765758 | Histogenetics, Ossining, USA |
| Cw*1619 | HN-3034950 | FJ792512 | Histogenetics, Ossining, USA |
| Cw*170102 | HN-727152 | FJ792497 | Histogenetics, Ossining, USA |
| Cw*170103 | HN-679965, HN-69216-8 |
FJ792510, FJ875596 |
Histogenetics, Ossining, USA |
| Cw*1706 | HN-72806-2 | FJ765996 | Histogenetics, Ossining, USA |
| DRB1*010117 | HN-38082-8 | FJ392259 | Histogenetics, Ossining, USA |
| DRB1*030108 | 09d05193 | FN563146 | Jacqy DH Anholts, Leiden, The Netherlands |
| DRB1*0352 | HN-80114-2 | FJ858908 | Histogenetics, Ossining, USA |
| DRB1*1188 | HN-55677-7 | FJ549415 | Histogenetics, Ossining, USA |
| DRB1*1189 | 09-2843 | GU060679 | Michele Curcio, Pisa, Italy |
| DRB1*1495 | HN-51663-1 | FJ502336 | Histogenetics, Ossining, USA |
| DRB1*1496 | 09-2790 | GU186854 | Kyung-won Kim, Seoul, South Korea |
| DRB4*0108 | Tokushima | AB510591 | Etsuko Lee, Tokushima, Japan |
Table 2: Confirmatory Sequences
| Sequence | Cell identification | Accession number | Submitting author |
|---|---|---|---|
| A*010106 | HN-04477-1 | GQ180284 | Histogenetics, Ossining, USA |
| A*0139 | HN-88851-1 | GQ160995 | Histogenetics, Ossining, USA |
| A*0140 | HN-98150-3, HN-32298-1, HN-09864-1, HN-90444-8, HN-23474-6, HN-33290-4, HN-33390-2, HN-41184-5, HN-28548-2 |
FJ997957, GQ160976, GQ161011, GQ345028, GQ401177, GQ401178, GQ401179, GQ859516, GQ859526 |
Histogenetics, Ossining, USA |
| A*020123 | HN-38885-6 | GQ240539 | Histogenetics, Ossining, USA |
| A*020124 | HN-01844-6 | GQ240547 | Histogenetics, Ossining, USA |
| A*020125 | HN-51902-7 | GQ859517 | Histogenetics, Ossining, USA |
| A*020502 | HN-83850-2, HN-52933-5, HN-02597-9 |
GQ180304, GQ180321, GQ240548 |
Histogenetics, Ossining, USA |
| A*030111 | HN-32658-6, HN-02317-9 |
GQ160999, GQ180305 |
Histogenetics, Ossining, USA |
| A*030114 | HN-48416-3, HN-74235-3, HN-22453-9, HN-16576-0, HN-42799-9, HN-94231-6, HN-3461618, HN-32569-1, HN-52644-0, HN-44681-1, HN-05098-4, HN-52525-8, HN-33985-5, HN-58033-4 |
GQ160996, GQ161022, GQ180290, GQ180298, GQ180324, GQ180335, GQ240356, GQ240541, GQ401175, GQ449621, GQ449622, GQ401175, GQ449621, GQ449622, GQ859512, GQ994053 |
Histogenetics, Ossining, USA |
| A*030115 | HN-08400-6 | GQ900560 | Histogenetics, Ossining, USA |
| A*0348 | HN-52782-1, HN-21690-2, HN-65267-9 |
GQ161002, GQ180293, GQ401183 |
Histogenetics, Ossining, USA |
| A*0349 | HN-69245-4 | GQ900559 | Histogenetics, Ossining, USA |
| A*0350 | HN-61931-3, HN-98248-5, HN-23778-0 |
GQ161001, GQ240545, GQ914780 |
Histogenetics, Ossining, USA |
| A*0353 | HN-19631-3 | GQ994043 | Histogenetics, Ossining, USA |
| A*0362 | HN-93337-4 | GQ160990 | Histogenetics, Ossining, USA |
| A*1146 | HN-36629-3 | GQ180288 | Histogenetics, Ossining, USA |
| A*1148 | HN-001504 | GQ240534 | Histogenetics, Ossining, USA |
| A*230102 | HN-03764-4, HN-06561-7, HN-40389-1, HN-57799-4 |
GQ245714, GQ449619, GQ994050, GQ994054 |
Histogenetics, Ossining, USA |
| A*240219 | HN-22305-5, HN-07962-6, HN-14637-8, HN-97781-6, HN-29993-5 |
GQ149259, GQ149288, GQ240537, GQ240544, GQ859518 |
Histogenetics, Ossining, USA |
| A*240223 | HN-52275-5 | GQ199690 | Histogenetics, Ossining, USA |
| A*2639 | HN-92817-8, HN-25550-0 |
FJ997936, GQ900563 |
Histogenetics, Ossining, USA |
| A*2639 | 93066816 | GU191547 | Daniel Fuerst, Ulm, Germany |
| A*290204 | HN-1915-3, HN-38969-3 |
FJ976751, GQ149251 |
Histogenetics, Ossining, USA |
| A*3029 | HN-08330-2, HN-68905-1, HN-54156-4, HN-54158-0, HN-54110-1, HN-54123-4 |
GQ180292, GQ180303, GQ240351, GQ240352, GQ240525, GQ345035 |
Histogenetics, Ossining, USA |
| A*3126 | HN-78362-1, HN-79551-8, HN-98435-1, HN-53488-9, HN-53647-0, HN-38472-2, HN-72564-3 |
GQ160988, GQ160989, GQ160992, GQ240527, GQ240528, GQ449620, GQ859507 |
Histogenetics, Ossining, USA |
| A*3127 | HN-82794-0, HN-92083-2, HN-51328-8, HN-86572-0 |
GQ161013, GQ254316, GQ449625, GQ914776 |
Histogenetics, Ossining, USA |
| A*320104 | HN-30229-2, HN-00356-4, HN-25975-5, HN-68512-9 |
FJ224236, GQ160971, GQ161005, GQ240542 |
Histogenetics, Ossining, USA |
| A*330103 | HN-24391-3 | GQ914775 | Histogenetics, Ossining, USA |
| A*3326 | HN-61409-1 | GQ401182 | Histogenetics, Ossining, USA |
| A*3327 | HN-01766-3, HN-55084-5 |
GQ160973, GQ240543 |
Histogenetics, Ossining, USA |
| A*6609 | HN-50709-6 | FJ997934 | Histogenetics, Ossining, USA |
| A*6611 | HN-92081 | FJ907384 | Histogenetics, Ossining, USA |
| A*9258 | HN-86446-8, HN-63730-8, HN-77431-0, HN-73984-9 |
GQ180322, GQ859520, GQ900557, GQ994041 |
Histogenetics, Ossining, USA |
| A*9260 | HN-38048-7 | GQ859519 | Histogenetics, Ossining, USA |
| A*9266 | HN-05493-4, HN-78285-9 |
GQ859525, GQ900556 |
Histogenetics, Ossining, USA |
| A*9280 | HN-12260-8 | GQ449615 | Histogenetics, Ossining, USA |
| B*0792 | HSR146198 | FN568353 | Hien Tran, Heidelberg, Germany |
| Cw*010208 | HN-20485-5 | GQ491100 | Histogenetics, Ossining, USA |
| Cw*0132 | HN-01902-2, HN-29077-1, HN-45369-1, HN-12267-3 |
GQ149303, GQ345071, GQ401221, GQ859570 |
Histogenetics, Ossining, USA |
| Cw*020207 | HN-06181-7, HN-42878-4, HN-15322-6, HN-55708-8 |
GQ254365, GQ401220, GQ859557, GQ859571 |
Histogenetics, Ossining, USA |
| Cw*0225Q | HN-24492-7 | GQ449662 | Histogenetics, Ossining, USA |
| Cw*0227 | HN-46734-8 | GQ900570 | Histogenetics, Ossining, USA |
| Cw*030307 | HN-26451-7 | GQ491098 | Histogenetics, Ossining, USA |
| Cw*030411 | HN-53119-1, HN-98763-2 |
GQ240477, GQ345091 |
Histogenetics, Ossining, USA |
| Cw*0353 | HN-45534-0 | GQ900584 | Histogenetics, Ossining, USA |
| Cw*0355 | HN-33333-1 | GQ401226 | Histogenetics, Ossining, USA |
| Cw*0356 | HN-13606-8 | GQ149300 | Histogenetics, Ossining, USA |
| Cw*0364 | HN-11079-3 | GQ491096 | Histogenetics, Ossining, USA |
| Cw*040108 | HN-23236-9, HN-34103-4, HN-62461-4 |
GQ401215, GQ900576, GQ900580 |
Histogenetics, Ossining, USA |
| Cw*040109 | HN-57446-9 | GQ401227 | Histogenetics, Ossining, USA |
| Cw*040110 | HN-81687-4, HN-41497-5, HN-22340-3, HN-13432-6, HN-22063-7 |
GQ180388, GQ254380, GQ401210, GQ401217, GQ449656 |
Histogenetics, Ossining, USA |
| Cw*040111 | HN-05538-3 | GQ401211 | Histogenetics, Ossining, USA |
| Cw*0439 | HN-56645-7, HN-62534-5 |
GQ345077, GQ345080 |
Histogenetics, Ossining, USA |
| Cw*0447 | HN-60806-9 | GQ859574 | Histogenetics, Ossining, USA |
| Cw*050108 | HN-06390-8, HN-50218-6, HN-N257957, HN-35804-0, HN-62913-6 |
GQ345073, GQ449654, GQ859556, GQ859563, GQ859564 |
Histogenetics, Ossining, USA |
| Cw*0524 | HN-37480-6 | GQ914782 | Histogenetics, Ossining, USA |
| Cw*0528 | HN-51622-5 | GQ254377 | Histogenetics, Ossining, USA |
| Cw*0529 | HN-14146, HN-14147 |
GQ410228, GQ401229 |
Histogenetics, Ossining, USA |
| Cw*060205 | HN-06177-5 | GQ240473 | Histogenetics, Ossining, USA |
| Cw*0623 | HN-91462-1, HN-58547-6, HN-10661-9 |
GQ468255, GQ491101, GQ900574 |
Histogenetics, Ossining, USA |
| Cw*0628 | HN-96000-1, HN-71664-3 |
GQ240474, GQ254379 |
Histogenetics, Ossining, USA |
| Cw*070208 | HN-71268-4, HN-61034-4, HN-08086-6, HN-84483-3, HN-17069-5, HN-46385-6, HN-74466-9 |
GQ161056, GQ180240, GQ240475, GQ254376, GQ345069, GQ401218, GQ900572 |
Histogenetics, Ossining, USA |
| Cw*070210 | HN-13035-6, HN-95859-1 |
GQ345075, GQ345076 |
Histogenetics, Ossining, USA |
| Cw*0768 | HN-81747-5, HN-08339-9, HN-74665-8, HN-03908-0 |
GQ149302, GQ240566, GQ345090, GQ345093 |
Histogenetics, Ossining, USA |
| Cw*0772 | HN-14296-7, HN-49344-4 |
FJ997968, GQ401206 |
Histogenetics, Ossining, USA |
| Cw*0780 | HN-N251395 | GQ240559 | Histogenetics, Ossining, USA |
| Cw*0790 | HN-22024-9 | GQ449658 | Histogenetics, Ossining, USA |
| Cw*080202 | HN-47110-8, HN-47121-5 |
GQ345088, GQ345089 |
Histogenetics, Ossining, USA |
| Cw*0828 | HN-92569-9, HN-39991-7 |
GQ161055, GQ468257 |
Histogenetics, Ossining, USA |
| Cw*120308 | HN-N252973, HN-38754-6 |
GQ345068, GQ900567 |
Histogenetics, Ossining, USA |
| Cw*1227 | HN-57019-7, HN-52660-0 |
GQ491103, GQ859576 |
Histogenetics, Ossining, USA |
| G*01010201 | BCI-14, BCI-19, CUI-80 | GQ996566 | Jorge Martinez-Laso, Madrid, Spain |
Table 3: Recently Published Sequences
| Sequence | References |
|---|---|
| A*01010101 | (1) |
| A*02010101 | (1) |
| A*03010101 | (1) |
| A*110101 | (1) |
| A*230101 | (1) |
| A*24020101 | (1) |
| A*260101 | (1) |
| A*29010101 | (1) |
| A*300101 | (1) |
| A*310102 | (1) |
| A*3116 | (2) |
| A*320101 | (1) |
| A*3219N | (3) |
| A*330301 | (1) |
| A*340101 | (1) |
| A*680102 | (1) |
| A*6901 | (1) |
| B*0777 | (4) |
| B*130101 | (5) |
| B*1325 | (5) |
| B*3950 | (3) |
| B*5161 | (6) |
| B*5317 | (6) |
| B*9551 | (6) |
| Cw*0124 | (7) |
| Cw*0130 | (8) |
| Cw*030202 | (9) |
| Cw*0361 | (10) |
| Cw*0525 | (3) |
| Cw*0822 | (11) |
| Cw*0825 | (3) |
| Cw*1222 | (12) |
| Cw*140201 | (9) |
References:
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