Nomenclature for Factors of the HLA System

November 2009

Compiled by Steven G. E. Marsh for the WHO Nomenclature Committee for Factors of the HLA System.

Published In:

The following sequences have been submitted to the Nomenclature Committee since the October 2009 nomenclature update and, following agreed policy, have been assigned official allele designations. Full details of all sequences will be published in a forthcoming report.

Below are listed the newly assigned sequences (Table 1) and confirmations of previously reported sequences (Table 2). The accession number of each sequence is given and these can be used to retrieve the sequence files from the EMBL, GenBank or DDBJ data libraries. Although accession numbers have been assigned by the data-libraries and most sequences are already available, there is still the possibility that an author may not yet have allowed the sequence to be released; in such a case you will have to contact the submitting author directly. Additional information pertaining to new sequences is often included in the publications describing these alleles; a listing of recent publications that describe new HLA sequences is given in Table 3.

All new and confirmatory sequences should now be submitted directly to the WHO Nomenclature Committee for Factors of the HLA System via the IMGT/HLA Database using the sequence submission tool provided. The IMGT/HLA Database may be accessed via the world wide web at : http://ww.ebi.ac.uk/imgt/hla/.

Table 1: New Sequences


Sequence Cell identification Accession number Submitting author
A*0370 BY00566 GU138060 Carolyn K Hurley, Washington DC, USA
A*0371 HT-59 GU169071 Min Yu, Chicago, USA
A*260113 HN-7541 FJ224228 Histogenetics, Ossining, USA
A*2922 DEDK698352 FN582331 Steven GE Marsh, London, United Kingdom
B*070219 JMDP01K046 AB512680 Kenji Tadokoro, Tokyo, Japan
B*130103 K34517 GU136390 Marie Lin, Taipei, Taiwan
B*350204 09218414 GU191548 Daniel Fuerst, Ulm, Germany
B*5729 SZGSQ-4 GU166293 Su-Qing Gao, Shenzhen, China
B*5827 DL-BK GU071234 BingShen Ke, Jinan, China
Cw*010209 HN-67204-1 FJ875627 Histogenetics, Ossining, USA
Cw*0134 PBMC-JQZ GQ365731 JianQiong Zhang, Nanjing, China
Cw*020209 HN-70709-9,
HN-28218-5,
HN-97117-5
FJ640584,
FJ976830,
FJ976839
Histogenetics, Ossining, USA
Cw*020210 HN-25390-3 FJ594638 Histogenetics, Ossining, USA
Cw*020211 HN-66330-9 FJ765993 Histogenetics, Ossining, USA
Cw*030206 HN-759098 FJ792493 Histogenetics, Ossining, USA
Cw*030415 HN-20607-9 FJ619432 Histogenetics, Ossining, USA
Cw*030416 HN-67433-1 FJ766000 Histogenetics, Ossining, USA
Cw*030417 HN-60094-6,
HN-56321-9,
HN-51699-3,
HN-51054-1,
HN-50983-2
FJ765995,
FJ875591,
FJ875592,
FJ875593,
FJ875594
Histogenetics, Ossining, USA
Cw*030418 HN-718581 FJ792503 Histogenetics, Ossining, USA
Cw*0377 HN-75897-9 FJ765749 Histogenetics, Ossining, USA
Cw*0378 HN-38248-9 FJ765876 Histogenetics, Ossining, USA
Cw*0379 HN-51098-8 FJ858899 Histogenetics, Ossining, USA
Cw*040113 HN-27574-4,
HN-68911-4,
HN-26496-7
FJ619434,
FJ765994,
FJ766001
Histogenetics, Ossining, USA
Cw*040114 HN-769287 FJ792490 Histogenetics, Ossining, USA
Cw*0450 HN-1252167 FJ392211 Histogenetics, Ossining, USA
Cw*0451 HN-9832463 FJ392221 Histogenetics, Ossining, USA
Cw*0452 HN-90881-3 FJ640585 Histogenetics, Ossining, USA
Cw*0453 HN-0650688 FJ792488 Histogenetics, Ossining, USA
Cw*0532 HN-06590-2,
HN-74682-6
FJ619423,
FJ969929
Histogenetics, Ossining, USA
Cw*0533 HN-76528-1,
HN-87304-0
FJ765751,
FJ765922
Histogenetics, Ossining, USA
Cw*0534 HN-36886-9,
HN-75619-4,
HN-76641-9
FJ392193,
FJ875589,
FJ969921
Histogenetics, Ossining, USA
Cw*070212 HN-8224910 FJ392227 Histogenetics, Ossining, USA
Cw*070213 HN-2762021 FJ792505 Histogenetics, Ossining, USA
Cw*0794 HN-08894-8 FJ619431 Histogenetics, Ossining, USA
Cw*0795 HN-61294-5,
HN-86379-4
FJ765746,
FJ976843
Histogenetics, Ossining, USA
Cw*0796 HN-4723-8 FJ765752 Histogenetics, Ossining, USA
Cw*0797 HN-16390-1,
HN-58064-0
FJ765763,
FJ875622
Histogenetics, Ossining, USA
Cw*0798N HN-12269-0 FJ875631 Histogenetics, Ossining, USA
Cw*0799 HN-30334-7 FJ392209 Histogenetics, Ossining, USA
Cw*0831 801P08, 902P08 FN568089 Sonia Nesci, Pesaro, Italy
Cw*120204 HN-5264226 FJ765988 Histogenetics, Ossining, USA
Cw*120309 HN-98468-9 FJ765762 Histogenetics, Ossining, USA
Cw*1229 HN-08004-5 FJ619436 Histogenetics, Ossining, USA
Cw*1230 HN-20602-2,
HN-40116-2,
HN-62540-6
FJ619437,
FJ976874,
FJ976876
Histogenetics, Ossining, USA
Cw*1231 HN-23222-7 FJ765764 Histogenetics, Ossining, USA
Cw*1415 HN-12308-0 FJ765923 Histogenetics, Ossining, USA
Cw*150205 HN-50699-6 FJ765998 Histogenetics, Ossining, USA
Cw*1524 HN-30608-6,
HN-28600-9
FJ765756,
FJ976807
Histogenetics, Ossining, USA
Cw*1525 G18106156010P GU133628 Dimitra Niokou, London, United Kingdom
Cw*160104 HN-751293,
HN-4604700
FJ792491,
FJ792511
Histogenetics, Ossining, USA
Cw*160202 HN-758777 FJ792492 Histogenetics, Ossining, USA
Cw*1618 HN-44614-8 FJ765758 Histogenetics, Ossining, USA
Cw*1619 HN-3034950 FJ792512 Histogenetics, Ossining, USA
Cw*170102 HN-727152 FJ792497 Histogenetics, Ossining, USA
Cw*170103 HN-679965,
HN-69216-8
FJ792510,
FJ875596
Histogenetics, Ossining, USA
Cw*1706 HN-72806-2 FJ765996 Histogenetics, Ossining, USA
DRB1*010117 HN-38082-8 FJ392259 Histogenetics, Ossining, USA
DRB1*030108 09d05193 FN563146 Jacqy DH Anholts, Leiden, The Netherlands
DRB1*0352 HN-80114-2 FJ858908 Histogenetics, Ossining, USA
DRB1*1188 HN-55677-7 FJ549415 Histogenetics, Ossining, USA
DRB1*1189 09-2843 GU060679 Michele Curcio, Pisa, Italy
DRB1*1495 HN-51663-1 FJ502336 Histogenetics, Ossining, USA
DRB1*1496 09-2790 GU186854 Kyung-won Kim, Seoul, South Korea
DRB4*0108 Tokushima AB510591 Etsuko Lee, Tokushima, Japan

Table 2: Confirmatory Sequences


Sequence Cell identification Accession number Submitting author
A*010106 HN-04477-1 GQ180284 Histogenetics, Ossining, USA
A*0139 HN-88851-1 GQ160995 Histogenetics, Ossining, USA
A*0140 HN-98150-3,
HN-32298-1,
HN-09864-1,
HN-90444-8,
HN-23474-6,
HN-33290-4,
HN-33390-2,
HN-41184-5,
HN-28548-2
FJ997957,
GQ160976,
GQ161011,
GQ345028,
GQ401177,
GQ401178,
GQ401179,
GQ859516,
GQ859526
Histogenetics, Ossining, USA
A*020123 HN-38885-6 GQ240539 Histogenetics, Ossining, USA
A*020124 HN-01844-6 GQ240547 Histogenetics, Ossining, USA
A*020125 HN-51902-7 GQ859517 Histogenetics, Ossining, USA
A*020502 HN-83850-2,
HN-52933-5,
HN-02597-9
GQ180304,
GQ180321,
GQ240548
Histogenetics, Ossining, USA
A*030111 HN-32658-6,
HN-02317-9
GQ160999,
GQ180305
Histogenetics, Ossining, USA
A*030114 HN-48416-3,
HN-74235-3,
HN-22453-9,
HN-16576-0,
HN-42799-9,
HN-94231-6,
HN-3461618,
HN-32569-1,
HN-52644-0,
HN-44681-1,
HN-05098-4,
HN-52525-8,
HN-33985-5,
HN-58033-4
GQ160996,
GQ161022,
GQ180290,
GQ180298,
GQ180324,
GQ180335,
GQ240356,
GQ240541,
GQ401175,
GQ449621,
GQ449622,
GQ401175,
GQ449621,
GQ449622,
GQ859512,
GQ994053
Histogenetics, Ossining, USA
A*030115 HN-08400-6 GQ900560 Histogenetics, Ossining, USA
A*0348 HN-52782-1,
HN-21690-2,
HN-65267-9
GQ161002,
GQ180293,
GQ401183
Histogenetics, Ossining, USA
A*0349 HN-69245-4 GQ900559 Histogenetics, Ossining, USA
A*0350 HN-61931-3,
HN-98248-5,
HN-23778-0
GQ161001,
GQ240545,
GQ914780
Histogenetics, Ossining, USA
A*0353 HN-19631-3 GQ994043 Histogenetics, Ossining, USA
A*0362 HN-93337-4 GQ160990 Histogenetics, Ossining, USA
A*1146 HN-36629-3 GQ180288 Histogenetics, Ossining, USA
A*1148 HN-001504 GQ240534 Histogenetics, Ossining, USA
A*230102 HN-03764-4,
HN-06561-7,
HN-40389-1,
HN-57799-4
GQ245714,
GQ449619,
GQ994050,
GQ994054
Histogenetics, Ossining, USA
A*240219 HN-22305-5,
HN-07962-6,
HN-14637-8,
HN-97781-6,
HN-29993-5
GQ149259,
GQ149288,
GQ240537,
GQ240544,
GQ859518
Histogenetics, Ossining, USA
A*240223 HN-52275-5 GQ199690 Histogenetics, Ossining, USA
A*2639 HN-92817-8,
HN-25550-0
FJ997936,
GQ900563
Histogenetics, Ossining, USA
A*2639 93066816 GU191547 Daniel Fuerst, Ulm, Germany
A*290204 HN-1915-3,
HN-38969-3
FJ976751,
GQ149251
Histogenetics, Ossining, USA
A*3029 HN-08330-2,
HN-68905-1,
HN-54156-4,
HN-54158-0,
HN-54110-1,
HN-54123-4
GQ180292,
GQ180303,
GQ240351,
GQ240352,
GQ240525,
GQ345035
Histogenetics, Ossining, USA
A*3126 HN-78362-1,
HN-79551-8,
HN-98435-1,
HN-53488-9,
HN-53647-0,
HN-38472-2,
HN-72564-3
GQ160988,
GQ160989,
GQ160992,
GQ240527,
GQ240528,
GQ449620,
GQ859507
Histogenetics, Ossining, USA
A*3127 HN-82794-0,
HN-92083-2,
HN-51328-8,
HN-86572-0
GQ161013,
GQ254316,
GQ449625,
GQ914776
Histogenetics, Ossining, USA
A*320104 HN-30229-2,
HN-00356-4,
HN-25975-5,
HN-68512-9
FJ224236,
GQ160971,
GQ161005,
GQ240542
Histogenetics, Ossining, USA
A*330103 HN-24391-3 GQ914775 Histogenetics, Ossining, USA
A*3326 HN-61409-1 GQ401182 Histogenetics, Ossining, USA
A*3327 HN-01766-3,
HN-55084-5
GQ160973,
GQ240543
Histogenetics, Ossining, USA
A*6609 HN-50709-6 FJ997934 Histogenetics, Ossining, USA
A*6611 HN-92081 FJ907384 Histogenetics, Ossining, USA
A*9258 HN-86446-8,
HN-63730-8,
HN-77431-0,
HN-73984-9
GQ180322,
GQ859520,
GQ900557,
GQ994041
Histogenetics, Ossining, USA
A*9260 HN-38048-7 GQ859519 Histogenetics, Ossining, USA
A*9266 HN-05493-4,
HN-78285-9
GQ859525,
GQ900556
Histogenetics, Ossining, USA
A*9280 HN-12260-8 GQ449615 Histogenetics, Ossining, USA
B*0792 HSR146198 FN568353 Hien Tran, Heidelberg, Germany
Cw*010208 HN-20485-5 GQ491100 Histogenetics, Ossining, USA
Cw*0132 HN-01902-2,
HN-29077-1,
HN-45369-1,
HN-12267-3
GQ149303,
GQ345071,
GQ401221,
GQ859570
Histogenetics, Ossining, USA
Cw*020207 HN-06181-7,
HN-42878-4,
HN-15322-6,
HN-55708-8
GQ254365,
GQ401220,
GQ859557,
GQ859571
Histogenetics, Ossining, USA
Cw*0225Q HN-24492-7 GQ449662 Histogenetics, Ossining, USA
Cw*0227 HN-46734-8 GQ900570 Histogenetics, Ossining, USA
Cw*030307 HN-26451-7 GQ491098 Histogenetics, Ossining, USA
Cw*030411 HN-53119-1,
HN-98763-2
GQ240477,
GQ345091
Histogenetics, Ossining, USA
Cw*0353 HN-45534-0 GQ900584 Histogenetics, Ossining, USA
Cw*0355 HN-33333-1 GQ401226 Histogenetics, Ossining, USA
Cw*0356 HN-13606-8 GQ149300 Histogenetics, Ossining, USA
Cw*0364 HN-11079-3 GQ491096 Histogenetics, Ossining, USA
Cw*040108 HN-23236-9,
HN-34103-4,
HN-62461-4
GQ401215,
GQ900576,
GQ900580
Histogenetics, Ossining, USA
Cw*040109 HN-57446-9 GQ401227 Histogenetics, Ossining, USA
Cw*040110 HN-81687-4,
HN-41497-5,
HN-22340-3,
HN-13432-6,
HN-22063-7
GQ180388,
GQ254380,
GQ401210,
GQ401217,
GQ449656
Histogenetics, Ossining, USA
Cw*040111 HN-05538-3 GQ401211 Histogenetics, Ossining, USA
Cw*0439 HN-56645-7,
HN-62534-5
GQ345077,
GQ345080
Histogenetics, Ossining, USA
Cw*0447 HN-60806-9 GQ859574 Histogenetics, Ossining, USA
Cw*050108 HN-06390-8,
HN-50218-6,
HN-N257957,
HN-35804-0,
HN-62913-6
GQ345073,
GQ449654,
GQ859556,
GQ859563,
GQ859564
Histogenetics, Ossining, USA
Cw*0524 HN-37480-6 GQ914782 Histogenetics, Ossining, USA
Cw*0528 HN-51622-5 GQ254377 Histogenetics, Ossining, USA
Cw*0529 HN-14146,
HN-14147
GQ410228,
GQ401229
Histogenetics, Ossining, USA
Cw*060205 HN-06177-5 GQ240473 Histogenetics, Ossining, USA
Cw*0623 HN-91462-1,
HN-58547-6,
HN-10661-9
GQ468255,
GQ491101,
GQ900574
Histogenetics, Ossining, USA
Cw*0628 HN-96000-1,
HN-71664-3
GQ240474,
GQ254379
Histogenetics, Ossining, USA
Cw*070208 HN-71268-4,
HN-61034-4,
HN-08086-6,
HN-84483-3,
HN-17069-5,
HN-46385-6,
HN-74466-9
GQ161056,
GQ180240,
GQ240475,
GQ254376,
GQ345069,
GQ401218,
GQ900572
Histogenetics, Ossining, USA
Cw*070210 HN-13035-6,
HN-95859-1
GQ345075,
GQ345076
Histogenetics, Ossining, USA
Cw*0768 HN-81747-5,
HN-08339-9,
HN-74665-8,
HN-03908-0
GQ149302,
GQ240566,
GQ345090,
GQ345093
Histogenetics, Ossining, USA
Cw*0772 HN-14296-7,
HN-49344-4
FJ997968,
GQ401206
Histogenetics, Ossining, USA
Cw*0780 HN-N251395 GQ240559 Histogenetics, Ossining, USA
Cw*0790 HN-22024-9 GQ449658 Histogenetics, Ossining, USA
Cw*080202 HN-47110-8,
HN-47121-5
GQ345088,
GQ345089
Histogenetics, Ossining, USA
Cw*0828 HN-92569-9,
HN-39991-7
GQ161055,
GQ468257
Histogenetics, Ossining, USA
Cw*120308 HN-N252973,
HN-38754-6
GQ345068,
GQ900567
Histogenetics, Ossining, USA
Cw*1227 HN-57019-7,
HN-52660-0
GQ491103,
GQ859576
Histogenetics, Ossining, USA
G*01010201 BCI-14, BCI-19, CUI-80 GQ996566 Jorge Martinez-Laso, Madrid, Spain

Table 3: Recently Published Sequences


Sequence References
A*01010101 (1)
A*02010101 (1)
A*03010101 (1)
A*110101 (1)
A*230101 (1)
A*24020101 (1)
A*260101 (1)
A*29010101 (1)
A*300101 (1)
A*310102 (1)
A*3116 (2)
A*320101 (1)
A*3219N (3)
A*330301 (1)
A*340101 (1)
A*680102 (1)
A*6901 (1)
B*0777 (4)
B*130101 (5)
B*1325 (5)
B*3950 (3)
B*5161 (6)
B*5317 (6)
B*9551 (6)
Cw*0124 (7)
Cw*0130 (8)
Cw*030202 (9)
Cw*0361 (10)
Cw*0525 (3)
Cw*0822 (11)
Cw*0825 (3)
Cw*1222 (12)
Cw*140201 (9)

References:

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