Nomenclature for Factors of the HLA System
June 2009
Compiled by Steven G. E. Marsh for the WHO Nomenclature Committee for Factors of the HLA System.
Published In:
- Tissue Antigens. 2009 74:364-6
- Human Immunology. 2009 70:869-71
- International Journal of Immunogenetics. 2009 36:391-3
The following sequences have been submitted to the Nomenclature Committee since the May 2009 nomenclature update and, following agreed policy, have been assigned official allele designations. Full details of all sequences will be published in a forthcoming report.
Below are listed the newly assigned sequences (Table 1) and confirmations of previously reported sequences (Table 2). The accession number of each sequence is given and these can be used to retrieve the sequence files from either the EMBL, GenBank or DDBJ data libraries. Although accession numbers have been assigned by the data libraries and most sequences are already available, there is still the possibility that an author may not yet have allowed the sequence to be released, in such a case you will have to contact the submitting author directly. Additional information pertaining to new sequences is often included in the publications describing these alleles, a listing of recent publications which describe new HLA sequences is given in Table 3.
All new and confirmatory sequences should now be submitted directly to the WHO Nomenclature Committee for Factors of the HLA System via the IMGT/HLA Database using the sequence submission tool provided. The IMGT/HLA Database may be accessed via the world wide web at : http://ww.ebi.ac.uk/imgt/hla/.
Table 1: New Sequences
| Sequence | Cell identification | Accession number | Submitting author |
|---|---|---|---|
| A*010108 | HN-2874373 | FJ224239 | Histogenetics, Ossining, USA |
| A*020132 | HN-00748-4, HN-15296-7, HN-56401-03 |
FJ392135, FJ619446, FJ765911 |
Histogenetics, Ossining, USA |
| A*030115 | HN-01935-0, HN-96260-4, HN-49798-4 |
FJ224209, FJ224231, FJ976755 |
Histogenetics, Ossining, USA |
| A*0355 | REC1109C14 | GQ250940 | Maria da Graca Bicalho, Curitiba, Brazil |
| A*0356 | HN-14964-2 | FJ222567 | Histogenetics, Ossining, USA |
| A*0357 | HN-70922-0 | FJ224172 | Histogenetics, Ossining, USA |
| A*0358 | HN-29857-0 | FJ224234 | Histogenetics, Ossining, USA |
| A*0359 | HN-1878805 | FJ224241 | Histogenetics, Ossining, USA |
| A*110114 | HN-63517-7 | FJ224221 | Histogenetics, Ossining, USA |
| A*1147 | HN-5915-1, HN-6711-2 |
FJ222571, FJ224175 |
Histogenetics, Ossining, USA |
| A*240221 | HN-03364-8 | FJ224179 | Histogenetics, Ossining, USA |
| A*2509 | HN-45030-2 | FJ224124 | Histogenetics, Ossining, USA |
| A*290204 | HN-97418-1, HN-24104-4 |
FJ224176, FJ224189 |
Histogenetics, Ossining, USA |
| A*2920 | HN-18834-1 | FJ222559 | Histogenetics, Ossining, USA |
| A*3126 | HN-28488-4, HN-02272-3, HN-52155-8, HN-87418-8, HN-69195-0, HN-88007-2, HN-70217-3, HN-62998-9, HN-15148-9, HN-45545-3 |
FJ224134, FJ224156, FJ224180, FJ224188, FJ224204, FJ224206, FJ765915, FJ976734, FJ976743, FJ976754 |
Histogenetics, Ossining, USA |
| A*3127 | HN-27846-7, HN-73973-6 |
FJ224182, FJ765932 |
Histogenetics, Ossining, USA |
| A*330103 | HN-36756-8 | FJ224192 | Histogenetics, Ossining, USA |
| A*3325 | PT08-278, PT08-283 |
GQ199711, GQ214006 |
Myoung Hee Park, Seoul, South Korea |
| A*3326 | HN-69923-0, HN-70027-7, HN-68836-6, HN-47189-8, |
FJ224138, FJ224139, FJ224161, FJ224200 |
Histogenetics, Ossining, USA |
| A*9286 | HN-5491441 | FJ224245 | Histogenetics, Ossining, USA |
| B*070211 | HN-03271-4 | FJ235022 | Histogenetics, Ossining, USA |
| B*0778 | HN-4811 | FJ234986 | Histogenetics, Ossining, USA |
| B*0779 | HN-53200-1 | FJ235002 | Histogenetics, Ossining, USA |
| B*0780 | HN-4604976 | FJ235012 | Histogenetics, Ossining, USA |
| B*0781 | HN-4287194 | FJ235017 | Histogenetics, Ossining, USA |
| B*0782 | HN-6387-3 | FJ235037 | Histogenetics, Ossining, USA |
| B*0783 | HN-70201-1 | FJ235050 | Histogenetics, Ossining, USA |
| B*080107 | HN-1269-9 | FJ235027 | Histogenetics, Ossining, USA |
| B*081202 | HN-51339-9 | FJ235008 | Histogenetics, Ossining, USA |
| B*0842 | HN-14418-1 | FJ235041 | Histogenetics, Ossining, USA |
| B*132202 | SZ-18 | FJ561483 | Hong-Yan Zou, Shenzhen, China |
| B*1326 | 54600326 | FJ898283 | Chuanfu Zhu, Jinan, China |
| B*150109 | HN-40602-7, HN-26429-0 |
FJ235049, FJ346246 |
Histogenetics, Ossining, USA |
| B*150302 | HN-4301284, HN-2455892 |
FJ235016, FJ765794 |
Histogenetics, Ossining, USA |
| B*150303 | HN-16009-3, HN-25061-3, HN-13580-4 |
FJ235021, FJ235028, FJ549413 |
Histogenetics, Ossining, USA |
| B*157802 | HN-42973-7 | FJ235026 | Histogenetics, Ossining, USA |
| B*1835 | 60734C32 | GQ250939 | Maria da Graca Bicalho, Curitiba, Brazil |
| B*1836 | HN-1500441 | FJ235019 | Histogenetics, Ossining, USA |
| B*1837 | HN-28873559 | FJ235020 | Histogenetics, Ossining, USA |
| B*2753 | HN-36132-9, HN-52286-2, HN-52328-2 |
FJ235009, FJ235010, FJ235011 |
Histogenetics, Ossining, USA |
| B*2754 | HN-1888119 | FJ235018 | Histogenetics, Ossining, USA |
| B*350109 | HN-27182-5 | FJ235034, FJ235035 |
Histogenetics, Ossining, USA |
| B*3715 | HN-85082-6 | FJ235023 | Histogenetics, Ossining, USA |
| B*410202 | HN-70545-3, HN-57639-1 |
FJ235051, FJ502330 |
Histogenetics, Ossining, USA |
| B*4212 | 60608C7 | GQ250938 | Maria da Graca Bicalho, Curitiba, Brazil |
| B*440206 | HN-20948-6 | FJ235015 | Histogenetics, Ossining, USA |
| B*440207 | HN-42052-0, HN-57175-4 |
FJ235024, FJ235035 |
Histogenetics, Ossining, USA |
| B*440208 | NT01072 | GQ251350 | Carolyn K Hurley, Washington DC, USA |
| B*4471 | HN-94480-0 | FJ235003 | Histogenetics, Ossining, USA |
| B*4472 | HN-3124406 | FJ235031 | Histogenetics, Ossining, USA |
| B*4473 | HN-38150-0, HN-22849-5 |
FJ235038, FJ346308 |
Histogenetics, Ossining, USA |
| B*4474 | HN-56735-9, HN-59941-4, HN-56314-7, HN-62281-0, HN-0696372 |
FJ235044, FJ346245, FJ853778, FJ866151, FJ392163 |
Histogenetics, Ossining, USA |
| B*4621 | SZGSQ-3 | GQ225741 | Su-Qing Gao, Shenzhen, China |
| B*5172 | HN-04865-0 | FJ235007 | Histogenetics, Ossining, USA |
| B*5173 | HN-2357049 | FJ235030 | Histogenetics, Ossining, USA |
| B*5215 | HN-45860-4 | FJ235005 | Histogenetics, Ossining, USA |
| B*5535 | 63203676 | FJ898284 | Chuanfu Zhu, Jinan, China |
| B*570104 | HN-95376-9 | FJ235001 | Histogenetics, Ossining, USA |
| B*5822 | HN-6298546 | FJ235000 | Histogenetics, Ossining, USA |
| B*9562 | HN-3334, HN-1088 |
FJ235004, FJ765539 |
Histogenetics, Ossining, USA |
| B*9563 | JMDP36K035 | AB477104 | Kenji Tadokoro, Tokyo, Japan |
| B*9564 | NT01070 | GQ251348 | Carolyn K Hurley, Washington DC, USA |
| Cw*050105 | CS00021 | GQ325308 | Kai Cao, Los Angeles, USA |
| Cw*070206 | SZBM655 | GQ266700 | Zhihui Deng, ShenZhen, China |
| Cw*0774 | C143474 | GQ260846 | Robert Endres, Tempe, USA |
| Cw*0827 | SZBM270 | GQ241930 | Zhihui Deng, ShenZhen, China |
| DRB1*010110 | 2718193 | FN395287 | Sabine Schuett, Berlin, Germany |
| DRB1*1181 | HN-07650-3 | FJ205616 | Histogenetics, Ossining, USA |
Table 2: Confirmatory Sequences
| Sequence | Cell identification | Accession number | Submitting author |
|---|---|---|---|
| A*0134N | 37935 | GQ281054 | Kai Cao, Los Angeles, USA |
| A*030106 | 79255 | AM746339 | Jacqy DH Anholts, Leiden, The Netherlands |
| A*030111 | HN-26124-9, HN-80480-6, HN095921-1, HN-79481-8, HN-59431-3, HN-45502-8 |
FJ222564, FJ224132, FJ765943, FJ907386, FJ940746, FJ976870 |
Histogenetics, Ossining, USA |
| A*0309 | NT01104 | GQ251365 | Carolyn K Hurley, Washington DC, USA |
| A*110201 | SZ-56 | FJ969874 | Hong-Yan Zou, Shenzhen, China |
| A*2304 | NT01103 | GQ251364 | Carolyn K Hurley, Washington DC, USA |
| A*240204 | CS00014 | GQ292546 | Kai Cao, Los Angeles, USA |
| A*2422 | CS00013 | GQ292545 | Kai Cao, Los Angeles, USA |
| A*2453 | CS00012 | GQ281056 | Kai Cao, Los Angeles, USA |
| A*9258 | HN-22292-8 | FJ222568 | Histogenetics, Ossining, USA |
| A*9273 | HN-08388-8, HN-37051-2 |
FJ222569, FJ792527 |
Histogenetics, Ossining, USA |
| B*1401 | SZ-91 | FJ986193 | Hong-Yan Zou, Shenzhen, China |
| B*1513 | SZ-51 | FJ986197 | Hong-Yan Zou, Shenzhen, China |
| B*152501 | SZ-102 | FJ986200 | Hong-Yan Zou, Shenzhen, China |
| B*152701 | SZ-79 | FJ986203 | Hong-Yan Zou, Shenzhen, China |
| B*1532 | SZ-85 | FJ986201 | Hong-Yan Zou, Shenzhen, China |
| B*1558 | SZ-101 | FJ986202 | Hong-Yan Zou, Shenzhen, China |
| B*2724 | SZ-33 | GQ304759 | Hong-Yan Zou, Shenzhen, China |
| B*2725 | SZ-93 | GQ118996 | Hong-Yan Zou, Shenzhen, China |
| B*350201 | SZ-96 | GQ119000 | Hong-Yan Zou, Shenzhen, China |
| B*350301 | SZ-83 | GQ118998 | Hong-Yan Zou, Shenzhen, China |
| B*350801 | SZ-95 | GQ119001 | Hong-Yan Zou, Shenzhen, China |
| B*3924 | CS00009 | GQ260164 | Kai Cao, Los Angeles, USA |
| B*3938Q | SZ-103 | GQ161927 | Hong-Yan Zou, Shenzhen, China |
| B*3939 | CS00011 | GQ281055 | Kai Cao, Los Angeles, USA |
| B*400101 | SZ-73 | GQ161930 | Hong-Yan Zou, Shenzhen, China |
| B*4027 | CS00008 | GQ259735 | Kai Cao, Los Angeles, USA |
| B*4040 | SZ-82 | GQ161929 | Hong-Yan Zou, Shenzhen, China |
| B*440302 | SZ-100 | GQ161933 | Hong-Yan Zou, Shenzhen, China |
| B*4427 | CS00017 | GQ301203 | Kai Cao, Los Angeles, USA |
| B*480301 | SZ-81 | GQ161935 | Hong-Yan Zou, Shenzhen, China |
| B*4804 | SZ-84 | GQ161934 | Hong-Yan Zou, Shenzhen, China |
| B*520102 | SZ-86 | GQ161945 | Hong-Yan Zou, Shenzhen, China |
| B*5401 | SZ-78 | GQ161937 | Hong-Yan Zou, Shenzhen, China |
| B*550201 | SZ-80 | GQ161946 | Hong-Yan Zou, Shenzhen, China |
| B*5601 | Sz-71 | GQ161938 | Hong-Yan Zou, Shenzhen, China |
| B*5603 | Sz-99 | GQ161939 | Hong-Yan Zou, Shenzhen, China |
| B*5604 | SZ-98 | GQ161940 | Hong-Yan Zou, Shenzhen, China |
| B*5901 | SZ-90 | GQ161941 | Hong-Yan Zou, Shenzhen, China |
| B*670102 | SZ-89 | GQ161948 | Hong-Yan Zou, Shenzhen, China |
| Cw*030201 | SZ-104 | FJ973626 | Hong-Yan Zou, Shenzhen, China |
| Cw*0306 | CS00019 | GQ301204 | Kai Cao, Los Angeles, USA |
| Cw*040401 | CS00015 | GQ292547 | Kai Cao, Los Angeles, USA |
| Cw*070109 | 07d01093 | AM749670 | Jacqy DH Anholts, Leiden, The Netherlands |
| Cw*0746 | CS00016 | GQ292548 | Kai Cao, Los Angeles, USA |
| Cw*1409 | 3987, 07d04084 |
AM849813 | Jacqy DH Anholts, Leiden, The Netherlands |
| Cw*1513 | SZ-24 | GQ304757 | Hong-Yan Zou, Shenzhen, China |
| DRB1*0343 | CS00007 | FJ986467 | Kai Cao, Los Angeles, USA |
| DRB1*111901 | CS00020 | GQ301205 | Kai Cao, Los Angeles, USA |
| DQB1*030103 | FFM52459 | FM995168 | Christian Seidl, Frankfurt am Main, Germany |
Table 3: Recently Published Sequences
| Sequence | References |
|---|---|
| B*2740 | (1) |
References
- Chen MJ, Yang TC, Chu CC, et al. Detection of a novel HLA-B27 allele, B*2740, in Taiwanese volunteer bone marrow donors by sequence-based typing: curiosity rewarded. Int J Immunogenet. 2009 36:207-11.
