Nomenclature for Factors of the HLA System

May 2009

Compiled by Steven G. E. Marsh for the WHO Nomenclature Committee for Factors of the HLA System.

Published In:

The following sequences have been submitted to the Nomenclature Committee since the April 2009 nomenclature update and, following agreed policy, have been assigned official allele designations. Full details of all sequences will be published in a forthcoming report.

Below are listed the newly assigned sequences (Table 1) and confirmations of previously reported sequences (Table 2). The accession number of each sequence is given and these can be used to retrieve the sequence files from either the EMBL, GenBank or DDBJ data libraries. Although accession numbers have been assigned by the data libraries and most sequences are already available, there is still the possibility that an author may not yet have allowed the sequence to be released, in such a case you will have to contact the submitting author directly. Additional information pertaining to new sequences is often included in the publications describing these alleles, a listing of recent publications which describe new HLA sequences is given in Table 3.

All new and confirmatory sequences should now be submitted directly to the WHO Nomenclature Committee for Factors of the HLA System via the IMGT/HLA Database using the sequence submission tool provided. The IMGT/HLA Database may be accessed via the world wide web at : http://ww.ebi.ac.uk/imgt/hla/.

Table 1: New Sequences


Sequence Cell identification Accession number Submitting author
A*0137 BY00469 FJ985987 Carolyn K Hurley, Washington DC, USA
A*0138 HN-06971-5,
HN-76157-8,
HN-26803-9		 FJ224151,
FJ224178,
FJ976756		 Histogenetics, Ossining, USA
A*0139 HN-74052-2 FJ224171 Histogenetics, Ossining, USA
A*0140 HN-70102-1,
HN-67074-7,
HN-70277-6		 FJ224194,
FJ785213,
FJ940763		 Histogenetics, Ossining, USA
A*0141 HN-75146-5 FJ224196 Histogenetics, Ossining, USA
A*0142 HN-42569-4 FJ224240 Histogenetics, Ossining, USA
A*020128 HN-B-181556 FJ224198 Histogenetics, Ossining, USA
A*020129 HN-76995-8 FJ224213 Histogenetics, Ossining, USA
A*020130 HN-41590-1,
HN-20662-3		 FJ224218,
FJ392141		 Histogenetics, Ossining, USA
A*020131 HN-3341893,
HN-01102-3,
HN-2119456		 FJ224237,
FJ224244,
FJ765889		 Histogenetics, Ossining, USA
A*020503 HN-50922-4 FJ224235 Histogenetics, Ossining, USA
A*022202 NT01044 FJ797359 Carolyn K Hurley, Washington DC, USA
A*030113 HN-45046-2 FJ222572 Histogenetics, Ossining, USA
A*030114 HN-59324-6,
HN-70577-3,
HN-40419-7,
HN-42295-8,
HN-B-175649,
HN-19428-2,
HN-43533-9,
HN-47828-5		 FJ222573,
FJ224177,
FJ224193,
FJ224195,
FJ224197,
FJ619445,
FJ976744,
FJ976868		 Histogenetics, Ossining, USA
A*0352 HN-35736-7 FJ222563 Histogenetics, Ossining, USA
A*0353 HN-09644-4,
HN-09305-2,
HN-08709-0		 FJ224131,
FJ619438,
FJ358635		 Histogenetics, Ossining, USA
A*0354 HN-94347-1 FJ224230 Histogenetics, Ossining, USA
A*110111 HN-9813716,
HN-4725344		 EU882865,
FJ765883		 Histogenetics, Ossining, USA
A*110112 HN-1643803 FJ224242 Histogenetics, Ossining, USA
A*110113 HN-92780-8 FJ358631 Histogenetics, Ossining, USA
A*1144 BY00467 FJ976702 Carolyn K Hurley, Washington DC, USA
A*1145 HN-68740-0 FJ224160 Histogenetics, Ossining, USA
A*1146 HN-17281-5 FJ224220 Histogenetics, Ossining, USA
A*260108 QianhefenA26 FJ810058 Jun He, Suzhou, China
A*260109 HN-77427-2 FJ224137 Histogenetics, Ossining, USA
A*260110 HN-32502-5 FJ224216 Histogenetics, Ossining, USA
A*260111 HN-49017-7 FJ224222 Histogenetics, Ossining, USA
A*2640 BY00466 FJ976695 Carolyn K Hurley, Washington DC, USA
A*3029 HN-63814-0,
HN-8355385,
HN-67231-2,
HN-20282-0,
HN-5746123		 FJ222566,
FJ875686,
FJ976741,
FJ976748,
FJ976733		 Histogenetics, Ossining, USA
A*3220 HN-72101-8,
HN-33132-1		 FJ224133,
FJ224219		 Histogenetics, Ossining, USA
A*330102 HN-12761-7 FJ224208 Histogenetics, Ossining, USA
A*3324 NT01062 FJ976688 Carolyn K Hurley, Washington DC, USA
A*6848 NT01063 FJ976687 Carolyn K Hurley, Washington DC, USA
A*9277 NT01027 FJ976685 Carolyn K Hurley, Washington DC, USA
A*9278 NT01055 FJ976701 Carolyn K Hurley, Washington DC, USA
A*9279 BY00471 FJ999994 Carolyn K Hurley, Washington DC, USA
A*9280 HN-24564-0 FJ224187 Histogenetics, Ossining, USA
A*9281 HN-79304-6 FJ224201 Histogenetics, Ossining, USA
A*9282 HN-20514-0 FJ224210 Histogenetics, Ossining, USA
A*9283 HN-56519-2,
HN-2453129,
HN-64358-3,
HN-0871736		 FJ224223,
FJ032365,
FJ502338,
FJ765887		 Histogenetics, Ossining, USA
A*9284 HN-40197-6 FJ224224 Histogenetics, Ossining, USA
A*9285 HN-04097-0 FJ224232 Histogenetics, Ossining, USA
B*070210 HN-62104-5,
HN-53909-8,
HN-87721-5,
HN-28858-1		 FJ234987,
FJ234999,
FJ346233,
FJ346326		 Histogenetics, Ossining, USA
B*0841 HN-49468-2 FJ234989 Histogenetics, Ossining, USA
B*1325 SZ-31 GQ141863 Hong-Yan Zou, Shenzhen, China
B*152502 HN-5592857,
HN-6100148,
HN-6100064		 FJ234993,
FJ392168,
FJ875664		 Histogenetics, Ossining, USA
B*2751 09-360 FJ985693 Margaret Chambers, Albuquerque, USA
B*2752 CHN73493 FJ966367 Helena Alves, Porto, Portugal
B*370106 HN-5845263 FJ234996 Histogenetics, Ossining, USA
B*4109 HN-47239-9 FJ234992 Histogenetics, Ossining, USA
B*4211 BY00465 FJ976694 Carolyn K Hurley, Washington DC, USA
B*440304 BY00472 GQ183832 Carolyn K Hurley, Washington DC, USA
B*440305 HN-0312291 FJ234994 Histogenetics, Ossining, USA
B*4470 HN-66349-2 FJ234990 Histogenetics, Ossining, USA
B*4620 HN-4246760 FJ234997 Histogenetics, Ossining, USA
B*5171 HN-64733-9 FJ234988 Histogenetics, Ossining, USA
B*5419 UD5749 GQ200019 Kyung Wha Lee, Anyang City, South Korea
B*5722 HN-52968-5,
HN-4824705		 FJ234991,
FJ765866		 Histogenetics, Ossining, USA
B*9561 ATAB3398AN FM211648 Ann-Margaret Little, Glasgow, United Kingdom
Cw*0128 NT01059 FJ976703 Carolyn K Hurley, Washington DC, USA
Cw*020208 BY00460 FJ976696 Carolyn K Hurley, Washington DC, USA
Cw*0228 HN-4042631 EU887013 Histogenetics, Ossining, USA
Cw*0359 BY00461 FJ976697 Carolyn K Hurley, Washington DC, USA
Cw*0360 NT01056 FJ976700 Carolyn K Hurley, Washington DC, USA
Cw*0361 SZ-32 GQ140233 Liang-Hong Cheng, Shenzhen, China
Cw*040109 HN-4383123 EU887014 Histogenetics, Ossining, USA
Cw*040110 J-08-7194 FJ655417 Hans Thude, Jena, Germany
Cw*0441 BY00470 FJ985988 Carolyn K Hurley, Washington DC, USA
Cw*0773 NT01060 FJ976690 Carolyn K Hurley, Washington DC, USA
Cw*0826N NT01061 FJ976689 Carolyn K Hurley, Washington DC, USA
Cw*1412 BY00462 FJ976691 Carolyn K Hurley, Washington DC, USA
Cw*1522 NT01058 FJ976698 Carolyn K Hurley, Washington DC, USA
G*01010302 CUI-65B FJ805839 Jorge Martinez-Laso, Madrid, Spain
DRB1*0122 0870 GQ148551 Zahra M. Kashi, Beaverton, USA
DRB1*030107 HN-36534-8 FJ205634 Histogenetics, Ossining, USA
DRB1*0343 49784 FN392687 Jayne Johnson, Pontyclun, United Kingdom
DRB1*0344 HN-32510-1 FJ197336 Histogenetics, Ossining, USA
DRB1*0345 HN-78699-5 FJ205617 Histogenetics, Ossining, USA
DRB1*0346 HN-44447-1 FJ205618 Histogenetics, Ossining, USA
DRB1*0347 HN-17865-8,
HN-21128-5		 FJ205638,
FJ205639		 Histogenetics, Ossining, USA
DRB1*0348 HN-01618-2 FJ217730 Histogenetics, Ossining, USA
DRB1*080104 BY00463 FJ976692 Carolyn K Hurley, Washington DC, USA
DRB1*110108 194854 FN390946 Klaus Witter, M�nchen, Germany
DRB1*110109 HN-704680-4 FJ205627 Histogenetics, Ossining, USA
DRB1*110110 HN-63310-7,
HN-87124-6,
HN-37349-5		 FJ205637,
FJ205640,
FJ538280		 Histogenetics, Ossining, USA
DRB1*110405 HN-70606-3 FJ217728 Histogenetics, Ossining, USA
DRB1*1174 HN-51123-7,
HN-51223-5		 FJ205621,
FJ205622		 Histogenetics, Ossining, USA
DRB1*1175 HN-50189-0 FJ205623 Histogenetics, Ossining, USA
DRB1*1176 HN-07646-3,
HN-41815-3,
HN-62807-4,
HN-77466-2,
HN-87457-4		 FJ205629,
FJ205631,
FJ205632,
FJ217722,
FJ952589		 Histogenetics, Ossining, USA
DRB1*1177 HN-62473-5 FJ205630 Histogenetics, Ossining, USA
DRB1*1178 HN-74879-2,
HN-96208-3		 FJ205635,
FJ766003		 Histogenetics, Ossining, USA
DRB1*1179 HN-27416-7 FJ217727 Histogenetics, Ossining, USA
DRB1*1180 HN-9179433 FJ217729 Histogenetics, Ossining, USA
DRB1*130104 HN-82107-5 FJ205628 Histogenetics, Ossining, USA
DRB1*130105 HN-82132-3 FJ217723 Histogenetics, Ossining, USA
DRB1*133302 HN-10912-6 FJ205642 Histogenetics, Ossining, USA
DRB1*133303 HN-015227-4 FJ205643 Histogenetics, Ossining, USA
DRB1*1389 HN-80814-7 FJ205624 Histogenetics, Ossining, USA
DRB1*1390 HN-98148-0,
HN-98052-4		 FJ205626,
FJ217721		 Histogenetics, Ossining, USA
DRB1*1391 HN-23595-3,
HN-62612-1		 FJ205636,
FJ205641		 Histogenetics, Ossining, USA
DRB1*1392 HN-1563225 FJ217724 Histogenetics, Ossining, USA
DRB1*1487 HN-47902-1,
HN-452094		 FJ205620,
FJ217726		 Histogenetics, Ossining, USA
DRB1*1488 HN-93263-2 FJ205625 Histogenetics, Ossining, USA
DRB1*1489 HN-10516-7 FJ205644 Histogenetics, Ossining, USA
DRB1*1490 HN-37025-8 FJ205645 Histogenetics, Ossining, USA
DQB1*0635 B00062 FJ912900 Keming Du, Shanghai, China
DPB1*2502 BY00464 FJ976693 Carolyn K Hurley, Washington DC, USA
DPB1*2602 194863 FN393829 Klaus Witter, M�nchen, Germany

Table 2: Confirmatory Sequences


Sequence Cell identification Accession number Submitting author
A*0103 SZ-59 FJ969856 Hong-Yan Zou, Shenzhen, China
A*020123 HN-50658-9,
HN-77485-1,
HN-31306-3,
HN-45398-1		 FJ224185,
FJ765931,
FJ785204,
FJ875542		 Histogenetics, Ossining, USA
A*020301 SZ-56 FJ969859 Hong-Yan Zou, Shenzhen, China
A*0207 SZ-57 FJ969857 Hong-Yan Zou, Shenzhen, China
A*0210 SZ-58 FJ969858 Hong-Yan Zou, Shenzhen, China
A*0302 SZ-62 FJ969862 Hong-Yan Zou, Shenzhen, China
A*0349 HN-22431-5,
HN-17777-8,
HN-8933692		 FJ224212,
FJ976760,
FJ392157		 Histogenetics, Ossining, USA
A*1120 NT01054 FJ976711 Carolyn K Hurley, Washington DC, USA
A*230102 HN-24793-3,
HN-07940-9,
HN-23088-9,
HN-36828-9,
HN-76176-8,
HN-57136-6,
HN-52147-3,
HN-1352361,
HN-98551-2		 FJ224186,
FJ619403,
FJ792526,
FJ600633,
FJ619408,
FJ619415,
FJ640589,
FJ907383,
FJ952580		 Histogenetics, Ossining, USA
A*240219 HN-86540-2,
HN-91110-0,
HN-56961-5,
HN-07579-9,
HN-78007-2,
HN-4246661,
HN-34236-8,
HN-19680-2,
HN-7003269,
HN-17031-3,
HN-77073-5		 FJ224169,
FJ224214,
FJ224233,
FJ224243,
FJ619402,
FJ619464,
FJ619393,
FJ619420,
FJ619471,
FJ797948,
FJ875543		 Histogenetics, Ossining, USA
A*240301 SZ-64 FJ969867 Hong-Yan Zou, Shenzhen, China
A*2407 SZ-66 FJ969864 Hong-Yan Zou, Shenzhen, China
A*2410 SZ-63 FJ969865 Hong-Yan Zou, Shenzhen, China
A*2420 SZ-57 FJ969866 Hong-Yan Zou, Shenzhen, China
A*2481 HN-3720876 EU882864 Histogenetics, Ossining, USA
A*2639 HN-79781-3,
HN-60788-4,
HN-83682-2		 FJ224199,
FJ875684,
FJ952579		 Histogenetics, Ossining, USA
A*3016 NT01053 FJ976710 Carolyn K Hurley, Washington DC, USA
A*310102 SZ-54 FJ969876 Hong-Yan Zou, Shenzhen, China
A*3109 NT01052 FJ976709 Carolyn K Hurley, Washington DC, USA
A*3218 HN-32257-6,
HN-44089-8		 FJ224215,
FJ976867		 Histogenetics, Ossining, USA
A*330101 SZ-60 FJ969869 Hong-Yan Zou, Shenzhen, China
A*330301 SZ-53 FJ969877 Hong-Yan Zou, Shenzhen, China
A*6901 SZ-61 FJ969870 Hong-Yan Zou, Shenzhen, China
A*7405 NT01065 FJ976712 Carolyn K Hurley, Washington DC, USA
A*9258 HN-00731-9,
HN-81176-3,
HN-22166-0,
HN-24072-8,
HN-30155-4,
HN-99545-7,
HN-95792-5		 FJ619443,
FJ619444,
FJ594704,
FJ594705,
FJ765897,
FJ765909,
FJ976871		 Histogenetics, Ossining, USA
B*070501 SZ-77 GQ161942 Hong-Yan Zou, Shenzhen, China
B*130101 SZ-74 FJ973631 Hong-Yan Zou, Shenzhen, China
B*1503 SZ-50 FJ986195 Hong-Yan Zou, Shenzhen, China
B*1518 SZ-72 FJ986198 Hong-Yan Zou, Shenzhen, China
B*270401 SZ-76 GQ118997 Hong-Yan Zou, Shenzhen, China
B*3905 SZ-69 GQ161926 Hong-Yan Zou, Shenzhen, China
B*5107 SZ-68 GQ161936 Hong-Yan Zou, Shenzhen, China
B*520101 SZ-75 GQ161944 Hong-Yan Zou, Shenzhen, China
B*670101 SZ-70 GQ161947 Hong-Yan Zou, Shenzhen, China
B*9513 BY00468 FJ976684 Carolyn K Hurley, Washington DC, USA
Cw*0307 NT01049 FJ976705 Carolyn K Hurley, Washington DC, USA
Cw*0407 NT01048 FJ976704 Carolyn K Hurley, Washington DC, USA
Cw*0408 NT01051 FJ976708 Carolyn K Hurley, Washington DC, USA
Cw*0706 7550800507 FJ785732 Yunping Xu, Shenzhen, China
Cw*1410 NT01050 FJ976707 Carolyn K Hurley, Washington DC, USA
Cw*1509 NT01047 FJ976706 Carolyn K Hurley, Washington DC, USA
G*01010301 CUI-65A FJ805838 Jorge Martinez-Laso, Madrid, Spain
DRB1*110601 92414 FM994148 Juergen Enczmann, Duesseldorf, Germany
DRB1*111201 44397 FM994152 Juergen Enczmann, Duesseldorf, Germany
DRB1*1118 126512 FM994149 Juergen Enczmann, Duesseldorf, Germany
DRB1*112701 64449 FM994151 Juergen Enczmann, Duesseldorf, Germany
DRB1*1132 37479 FM994150 Juergen Enczmann, Duesseldorf, Germany
DRB1*1134 67364 FM994153 Juergen Enczmann, Duesseldorf, Germany
DRB1*1135 45982 FM994154 Juergen Enczmann, Duesseldorf, Germany
DRB1*1139 43096 FM994155 Juergen Enczmann, Duesseldorf, Germany
DRB1*1169 HN-48662-3 FJ217725 Histogenetics, Ossining, USA
DRB1*1387 HN-66888-8 FJ205619 Histogenetics, Ossining, USA
DRB1*1482 HN-53927-1 FJ205633 Histogenetics, Ossining, USA

Table 3: Recently Published Sequences


Sequence References
A*1136 (1)
A*1138 (1)
A*3020 (2)
B*4456N (3)
B*461301 (4)
B*4614 (4)
B*4618 (4)
B*5410 (5)
B*5904 (6)
B*9550 (7)
Cw*0223 (8)
Cw*0348 (9)
Cw*070403 (8)
Cw*0757 (8)
Cw*0817 (10)
Cw*1705 (8)
DRB1*0478 (11)
DRB1*1217 (12)
DQB1*030103 (13)
DQB1*0323 (14)
DQB1*0505 (13)

 

References

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