Nomenclature for Factors of the HLA System
June 2008
Compiled by Steven GE Marsh for the WHO Nomenclature Committee for Factors of the HLA System.
Published In:
- Tissue Antigens. 2008 72:412-3
- Human Immunology. 2008 69:588-90
- International Journal of Immunogenetics. 2008 35:357-8
The following sequences have been submitted to the Nomenclature Committee since the May 2008 nomenclature update and, following agreed policy, have been assigned official allele designations. Full details of all sequences will be published in a forthcoming report.
Below are listed the newly assigned sequences (Table 1) and confirmations of previously reported sequences (Table 2). The accession number of each sequence is given and these can be used to retrieve the sequence files from either the EMBL, GenBank or DDBJ data libraries. Although accession numbers have been assigned by the data libraries and most sequences are already available, there is still the possibility that an author may not yet have allowed the sequence to be released, in such a case you will have to contact the submitting author directly. Additional information pertaining to new sequences is often included in the publications describing these alleles, a listing of recent publications which describe new HLA sequences is given in Table 3.
All new and confirmatory sequences should now be submitted directly to the WHO Nomenclature Committee for Factors of the HLA System via the IMGT/HLA Database using the sequence submission tool provided. The IMGT/HLA Database may be accessed via the world wide web at : http://www.ebi.ac.uk/imgt/hla/.
Table 1: New Sequences
| Sequence | Cell identification | Accession number | Submitting Author |
|---|---|---|---|
| A*1136 | B23144 | EU741677 | Lixing Yan, Hangzhou, China |
| A*2491 | CB5943 | EU741678 | Lixing Yan, Hangzhou, China |
| A*3319 | BY00326 | EU827505 | Carolyn K Hurley, Washington DC, USA |
| A*9248 | BY00332 | EU812537 | Carolyn K Hurley, Washington DC, USA |
| B*4092 | 46531 | FM161906 | Jane Rowlands, Pontyclun, United Kingdom |
| B*4093 | RitNEW | EU785971 | Noureddine Berka, Calgary, Canada |
| B*440205 | 8/003970 | FM174682 | Anne Dormoy, Strasbourg, France |
| B*446402 | RIFFMic | FM160944 | Anne Dormoy, Strasbourg, France |
| Cw*0222 | 41873 | FM164942 | Jane Rowlands, Pontyclun, United Kingdom |
| Cw*0350 | 25089 | AB439293 | Yukari Kuroda, Fukuoka, Japan |
| Cw*0434 | 41718 | FM164941 | Jane Rowlands, Pontyclun, United Kingdom |
| G*0112 | Roger535 | EU750733 | Michel Roger, Montreal, Canada |
| G*0113N | 7a095 | EU750734 | Michel Roger, Montreal, Canada |
| G*0114 | BCCR4989, b007, HLA4 |
EU750735 | Michel Roger, Montreal, Canada |
| G*0115 | BCCR1016 | EU750736 | Michel Roger, Montreal, Canada |
| G*0116 | BCCR996 | EU750737 | Michel Roger, Montreal, Canada |
| DRB1*010106 | 36573 | AM992171 | Juergen Enczmann, Duesseldorf, Germany |
| DRB1*010107 | 47995 | AM992172 | Juergen Enczmann, Duesseldorf, Germany |
| DRB1*1003 | 55328 | AM992173 | Juergen Enczmann, Duesseldorf, Germany |
| DRB1*131102 | BY00337 | EU812540 | Carolyn K Hurley, Washington DC, USA |
| DRB1*1384 | BY00338 | EU812541 | Carolyn K Hurley, Washington DC, USA |
| DRB1*1385 | BY00340 | EU826130 | Carolyn K Hurley, Washington DC, USA |
| DRB1*1386 | BY00339 | EU826129 | Carolyn K Hurley, Washington DC, USA |
| DRB1*1481 | BY00334 | EU812536 | Carolyn K Hurley, Washington DC, USA |
| DPA1*010602 | ML2560 | EU729350 | Ma Luo, Winnipeg, Manitoba, Canada |
Table 2: Confirmatory Sequences
| Sequence | Cell Identification | Accession Number | Submitting Author |
|---|---|---|---|
| A*0115N | FRFPO06277 | FM164485 | Anne Dormoy, Strasbourg, France |
| A*2636 | HENAN11 | EU785343 | Bowei Zhang, Zhengzhou, China |
| B*1573 | 0004268 | EU715289 | Francisco de Paula Sanchez Gordo, Malaga, Spain |
| B*5155 | BY00341 | EU826135 | Carolyn K Hurley, Washington DC, USA |
| DRB1*0307 | NT00982 | EU812544 | Carolyn K Hurley, Washington DC, USA |
| DRB1*0414 | NT00980 | EU812546 | Carolyn K Hurley, Washington DC, USA |
| DRB1*0808 | NT00979 | EU812543 | Carolyn K Hurley, Washington DC, USA |
| DRB1*1133 | NT00984 | EU826133 | Carolyn K Hurley, Washington DC, USA |
| DRB1*1135 | NT00986 | EU826131 | Carolyn K Hurley, Washington DC, USA |
| DRB1*1141 | NT00978 | EU812542 | Carolyn K Hurley, Washington DC, USA |
| DRB1*1208 | BY00335 | EU812538 | Carolyn K Hurley, Washington DC, USA |
| DRB1*1338 | NT00983 | EU826134 | Carolyn K Hurley, Washington DC, USA |
| DRB1*1382 | BY00336 | EU812539 | Carolyn K Hurley, Washington DC, USA |
| DRB1*1429 | NT00985 | EU826132 | Carolyn K Hurley, Washington DC, USA |
| DRB1*1448 | NT00981 | EU812545 | Carolyn K Hurley, Washington DC, USA |
Table 3: Recently Published Sequences
| Sequence | References |
|---|---|
| A*2485 | (1) |
| A*3315 | (2) |
| DRB1*030105 | (3) |
| DRB1*040304 | (3) |
| DRB1*0459 | (3) |
| DRB1*0906 | (3) |
| DRB1*1156 | (3) |
| DRB1*135002 | (4) |
| DRB1*1464 | (3) |
| DRB1*1468 | (3) |
| DRB1*1522 | (3) |
| DQB1*0205 | (3) |
| DQB1*030104 | (3) |
| DQB1*0320 | (3) |
| DQB1*0321 | (3) |
References
- Li Z, Zou HY, Cheng LH, Jin SZ, Wang DM, Deng ZH. A new HLA-A*24 variant, A*2485, identified by sequence-based typing in a Chinese individual. Tissue Antigens. 2008 72:75-6
- Lim J, Kim Y, Han K, Kim HJ, Min WS. A novel HLA-A*3315 allele identified by haplotype-specific extraction and sequence-based typing. Tissue Antigens. 2008 72:76-7
- Lazaro AM, Xiao Y, Masaberg C, et al. Novel alleles at the HLA-DRB1 and -DQB1 loci. Tissue Antigens. 2008 72:72-4
- Yan LX, Zhu FM, He YM. A novel HLA-DRB1*135002 allele was identified in a cord blood donor. Tissue Antigens. 2008 72:78-9
