Nomenclature for Factors of the HLA System
April 2004
Compiled by Steven GE Marsh for the WHO Nomenclature Committee for Factors of the HLA System.
Published In:
- Tissue Antigens. 2008 72:221-3
- Human Immunology. 2008 69:526-8
- International Journal of Immunogenetics. 2008 35:349-51
The following sequences have been submitted to the Nomenclature Committee since the March 2008 nomenclature update and, following agreed policy, have been assigned official allele designations. Full details of all sequences will be published in a forthcoming report.
Below are listed the newly assigned sequences (Table 1) and confirmations of previously reported sequences (Table 2). The accession number of each sequence is given and these can be used to retrieve the sequence files from the EMBL, GenBank or DDBJ data libraries. Although accession numbers have been assigned by the data libraries and most sequences are already available, there is still the possibility that an author may not yet have allowed the sequence to be released, in such a case you will have to contact the submitting author directly. Additional information pertaining to new sequences is often included in the publications describing these alleles, a listing of recent publications which describe new HLA sequences is given in Table 3.
All new and confirmatory sequences should now be submitted directly to the WHO Nomenclature Committee for Factors of the HLA System via the IMGT/HLA Database using the sequence submission tool provided. The IMGT/HLA Database may be accessed via the world wide web at : http://www.ebi.ac.uk/imgt/hla/.
Table 1: New Sequences
| Sequence | Cell Identification | Accession Number | Submitting Author |
|---|---|---|---|
| A*112402 | JMDP01K007 | AB430468 | Kenji Tadokoro, Tokyo, Japan |
| A*240216 | JMDP01K008 | AB434096 | Kenji Tadokoro, Tokyo, Japan |
| A*2636 | CHA06-0792 | EU557970 | HyeYoung Seong, Seongnam, South Korea |
| A*2636 | 016149 | EU627183 | Jianping Li, Shenyang, Liaoning, China |
| A*2637 | 0200800714 | AM981205 | Silvia Ulrich, Graz, Austria |
| A*3025 | 0004123 | EU623422 | Francisco de Paula Sanchez Gordo, Malaga, Spain |
| A*9242 | JMDP01K002 | AB427094 | Kenji Tadokoro, Tokyo, Japan |
| A*9243 | JMDP01K003 | AB429008 | Kenji Tadokoro, Tokyo, Japan |
| A*9244 | JMDP01K004 | AB429218 | Kenji Tadokoro, Tokyo, Japan |
| A*9245 | BJ54 | EU649706 | Zhixin Zhang, Beijing, China |
| B*0765 | LUMC-B47 | AM946388 | Jacqy DH Anholts, Leiden, The Netherlands |
| B*1322 | BY00309 | EU643607 | Carolyn K Hurley, Washington DC, USA |
| B*1409 | BY00313 | EU643603 | Carolyn K Hurley, Washington DC, USA |
| B*152703 | SZ-13 | EU617016 | Hong-Yan Zou, Shenzhen, China |
| B*2743 | BY00318 | EU643598 | Carolyn K Hurley, Washington DC, USA |
| B*3589 | VTIS163461 | EU589203 | Maude Phipps, Kuala Lumpur, Malaysia |
| B*3590 | BY00316 | EU643600 | Carolyn K Hurley, Washington DC, USA |
| B*3591 | BY00319 | EU643597 | Carolyn K Hurley, Washington DC, USA |
| B*390105 | BY00306 | EU643610 | Carolyn K Hurley, Washington DC, USA |
| B*4089 | DEDKM740290 | AM980943 | Anne Dormoy, Strasbourg, France |
| B*4090 | BY00304 | EU643612 | Carolyn K Hurley, Washington DC, USA |
| B*4509 | MO-19507 | EU517717 | Gisele Rampim, Sao Paulo, Brazil |
| B*5156 | BY00305 | EU643611 | Carolyn K Hurley, Washington DC, USA |
| B*5213 | BY00312 | EU643604 | Carolyn K Hurley, Washington DC, USA |
| B*5531 | BY00317 | EU643599 | Carolyn K Hurley, Washington DC, USA |
| B*5717 | BY00315 | EU643601 | Carolyn K Hurley, Washington DC, USA |
| B*5818 | BY00310 | EU643605 | Carolyn K Hurley, Washington DC, USA |
| B*9547 | BY00314 | EU643602 | Carolyn K Hurley, Washington DC, USA |
| Cw*0121 | SZ-12 | EU617015 | Zhen Li, Shenzhen, China |
| Cw*0755N | MHHZ-00020178 | AM945965 | Rainer Blasczyk, Hannover, Germany |
| Cw*0756 | BJ53 | EU594580 | Zhixin Zhang, Beijing, China |
| DRB1*0474 | SI772 | AM947655 | Jean-Marie Tiercy, Geneva, Switzerland |
| DRB1*0907 | AS2054 | AM947068 | Xiang Liu, Beijing, China |
| DRB1*1478 | HistoCB69685 | EU588391 | Hoon Han, Seoul, South Korea |
| DRB1*1479 | NT00788 | EU643616 | Carolyn K Hurley, Washington DC, USA |
| DQB1*0322 | 175842 | AM944346 | Klaus Witter, M�nchen, Germany |
| DQB1*060104 | BJ52 | EU594579 | Zhixin Zhang, Beijing, China |
Table 2: Confirmatory Sequences
| Sequence | Cell Identification | Accession Number | Submitting Author |
|---|---|---|---|
| A*0260 | BRABRI | EU580406 | Youri Serov, Indianapolis, USA |
| A*0276 | JMDP01K005 | AB429497 | Kenji Tadokoro, Tokyo, Japan |
| A*1113 | JMDP01K006 | AB430331 | Kenji Tadokoro, Tokyo, Japan |
| B*0742 | 4229311 | AM931289 | Laura Hammond, Auckland, New Zealand |
| B*1825 | BY00321 | EU643595 | Carolyn K Hurley, Washington DC, USA |
| B*356802 | BY00296 | EU557367 | Carolyn K Hurley, Washington DC, USA |
| B*4059 | BY00307 | EU643609 | Carolyn K Hurley, Washington DC, USA |
| B*4064 | BY00320 | EU643596 | Carolyn K Hurley, Washington DC, USA |
| B*4209 | BY00308 | EU643608 | Carolyn K Hurley, Washington DC, USA |
| B*5155 | BY00290 | EU557368 | Carolyn K Hurley, Washington DC, USA |
| B*5315 | BY00311 | EU643606 | Carolyn K Hurley, Washington DC, USA |
| DRB1*0441 | NT00791 | EU643613 | Carolyn K Hurley, Washington DC, USA |
| DRB1*1121 | NT00790 | EU643614 | Carolyn K Hurley, Washington DC, USA |
| DRB1*1304 | 40267 | AM949862 | Thibaut Gervais, Brussels, Belgium |
| DRB1*1474 | 39756 | AM982721 | Thibaut Gervais, Brussels, Belgium |
| DRB1*1524 | NT00789 | EU643615 | Carolyn K Hurley, Washington DC, USA |
Table 3: Recently Published Sequences
| Sequence | References |
|---|---|
| A*0339 | (1) |
| A*240215 | (2) |
| A*310103 | (3) |
| A*9216 | (4) |
| A*9237 | (5) |
| B*0745 | (6) |
| B*0826 | (6) |
| B*0828 | (7) |
| B*0831 | (6) |
| B*2731 | (6) |
| B*350106 | (6) |
| B*350402 | (6) |
| B*3566 | (6) |
| B*356801 | (6) |
| B*370102 | (6) |
| B*3711 | (6) |
| B*380102 | (6) |
| B*3813 | (6) |
| B*3935 | (6) |
| B*3939 | (6) |
| B*4108 | (6) |
| B*4209 | (6) |
| B*4444 | (6) |
| B*4448 | (6) |
| B*480302 | (6) |
| B*4815 | (6) |
| B*5140 | (6) |
| B*5411 | (8) |
| B*5523 | (6) |
| B*5529 | (9) |
| B*5617 | (6) |
| B*570103 | (6) |
| B*5710 | (6) |
| B*9505 | (6) |
| B*9510 | (6) |
| B*9519 | (6) |
| B*9531 | (3) |
| G*010113 | (10) |
| DRB1*116502 | (11) |
| DQB1*0634 | (12) |
References
- Balas A, Garcia-Sanchez F, Bustamante L, Vicario JL. New HLA-A allele, A*0339, identified in a Spanish patient. Tissue Antigens. 2008 71:478.
- Emmerich F, Schonemann C, Hartmann S, Salama A. Identification of the novel HLA-A*240215 allele by haplotype-specific sequencing. Tissue Antigens. 2008 71:481-2.
- Frison S, Longhi E, Andreini E, Poli F, Scalamogna M. Characterization of two novel HLA class I alleles: HLA-A*310103 and HLA-B*9531. Int J Immunogenet. 2008 35:193-5.
- Jiang W, Zhang JQ, Pan N, Xu JH, Xie W. Identification of a novel HLA-A allele, HLA-A*9216. Tissue Antigens. 2008 71:479-80. Kelsch R, Binder TM, Sibrowski W. Identification of the novel allele HLA-A*9237 in peripheral blood of a bone marrow donor. Tissue Antigens. 2008 71:480-1.
- Lazaro AM, Xiao Y, Cao K, et al. Expanding diversity at the HLA-B locus: 28 novel HLA-B alleles. Tissue Antigens. 2008 71:471-4.
- Brixner V, Richter R, Bader P, Seifried E, Seidl C. A new HLA-B*08 allele, HLA-B*0828, found in two voluntary stem cell donors. Tissue Antigens. 2008 71:482-3.
- Yan LN, Li SY, Dong Z, et al. Identification of a novel HLA-B*54 allele, B*5411, by sequence-based typing in a Chinese individual. Tissue Antigens. 2008 71:484-5.
- Emmerich F, Schonemann C, Galicki L, Salama A. Identification of a novel HLA-B allele, HLA-B*5529, by haplotype-specific sequencing. Tissue Antigens. 2008 71:486.
- 1Kang H, Yun HS, Lee JK, Kwack K. Identification of a novel HLA-G allele, HLA-G*010113, in a Korean individual. Tissue Antigens. 2008 71:492-4.
- Serov Y, Hommel-Berrey G, Lobashevsky A. Identification of a novel HLA-DRB1 allele, DRB1*116502, by sequence-based typing in an African-American individual. Tissue Antigens. 2008 71:489-90.
- Witter K, Albert T, Zahn R, Kauke T. HLA-DQB1*0634, a novel DQB1 allele found by high-resolution HLA typing of a sibling pair for potential bone marrow transplantation. Tissue Antigens. 2008 71:486-8.
