Nomenclature for Factors of the HLA System
March 2008
Compiled by Steven G. E. Marsh for the WHO Nomenclature Committee for Factors of the HLA System.
Published In:
- Tissue Antigens. 2008 72:84-6
- Human Immunology. 2008 69:380-2
- International Journal of Immunogenetics. 2008 35:347-8
The following sequences have been submitted to the Nomenclature Committee since the February 2008 nomenclature update and, following agreed policy, have been assigned official allele designations. Full details of all sequences will be published in a forthcoming report.
Below are listed the newly assigned sequences (Table 1) and confirmations of previously reported sequences (Table 2). The accession number of each sequence is given and these can be used to retrieve the sequence files from either the EMBL, GenBank or DDBJ data libraries. Although accession numbers have been assigned by the data libraries and most sequences are already available, there is still the possibility that an author may not yet have allowed the sequence to be released, in such a case you will have to contact the submitting author directly. Additional information pertaining to new sequences is often included in the publications describing these alleles, a listing of recent publications which describe new HLA sequences is given in Table 3.
All new and confirmatory sequences should now be submitted directly to the WHO Nomenclature Committee for Factors of the HLA System via the IMGT/HLA Database using the sequence submission tool provided. The IMGT/HLA Database may be accessed via the world wide web at : http://www.ebi.ac.uk/imgt/hla/.
Table 1: New Sequences
| Sequence | Cell Identification | Accession Number | Submitting Author |
|---|---|---|---|
| A*02010103 | HSR131658 | AM943368 | Hien Tran, Heidelberg, Germany |
| A*020606 | JMDP01K001 | AB427093 | Kenji Tadokoro, Tokyo, Japan |
| A*2486N | HZB10788 | EF062307 | Lixing Yan, Hangzhou, China |
| A*3122 | 012948 | EU580147 | Jianping Li, Shenyang, Liaoning, China |
| A*3316 | OLMEMIGU01 | EU480687 | Peter Stastny, Dallas, Texas, USA |
| A*3317 | ZJCB5940 | EU554565 | Lixing Yan, Hangzhou, China |
| A*9241 | CS00001, CS00002 |
EU559334, EU559335 |
Kai Cao, Los Angeles, USA |
| B*072202 | BY00278 | EU522472 | Carolyn K Hurley, Washington DC, USA |
| B*0764 | BY00282 | EU522468 | Carolyn K Hurley, Washington DC, USA |
| B*0836 | BY00283 | EU522467 | Carolyn K Hurley, Washington DC, USA |
| B*1408 | BY00286 | EU555330 | Carolyn K Hurley, Washington DC, USA |
| B*1829 | BY00281 | EU522469 | Carolyn K Hurley, Washington DC, USA |
| B*2741 | BY00298 | EU555320 | Carolyn K Hurley, Washington DC, USA |
| B*2742 | BY00292 | EU555325 | Carolyn K Hurley, Washington DC, USA |
| B*350107 | CS00004 | EU564807 | Kai Cao, Los Angeles, USA |
| B*356802 | BY00280, BY00295 |
EU522470, EU555322 |
Carolyn K Hurley, Washington DC, USA |
| B*391902 | BY00299 | EU555319 | Carolyn K Hurley, Washington DC, USA |
| B*4087 | BY00271 | EU522479 | Carolyn K Hurley, Washington DC, USA |
| B*4088 | ZJCB5764 | EU554563 | Lixing Yan, Hangzhou, China |
| B*4460 | BY00274 | EU522476 | Carolyn K Hurley, Washington DC, USA |
| B*4508 | BY00273 | EU522477 | Carolyn K Hurley, Washington DC, USA |
| B*4614 | ZJCB5857 | EU554564 | Lixing Yan, Hangzhou, China |
| B*510109 | BY00302 | EU555316 | Carolyn K Hurley, Washington DC, USA |
| B*512402 | 07-2151 | EU547797 | Kyung-won Kim, Seoul, South Korea |
| B*5153 | BY00297 | EU555321 | Carolyn K Hurley, Washington DC, USA |
| B*5154 | BY00291 | EU555326 | Carolyn K Hurley, Washington DC, USA |
| B*5155 | BY00287 | EU555329 | Carolyn K Hurley, Washington DC, USA |
| B*5212 | EPM-17177 | EU517716 | Gisele Rampim, Sao Paulo, Brazil |
| B*5316 | BY00300 | EU555318 | Carolyn K Hurley, Washington DC, USA |
| B*5622 | BY00284 | EU522466 | Carolyn K Hurley, Washington DC, USA |
| B*5623 | BY00272 | EU522478 | Carolyn K Hurley, Washington DC, USA |
| B*5817N | BY00303 | EU564105 | Carolyn K Hurley, Washington DC, USA |
| B*8104N | BY00279 | EU522471 | Carolyn K Hurley, Washington DC, USA |
| B*9543 | BY00285 | EU522465 | Carolyn K Hurley, Washington DC, USA |
| B*9544 | CTJ-18300 | EU547493 | Lina Yan, Tianjin, China |
| B*9545 | BY00288 | EU555328 | Carolyn K Hurley, Washington DC, USA |
| B*9546 | CS00003 | EU564806 | Kai Cao, Los Angeles, USA |
| B*9546 | HCP-95 | AM711637 | Oscar de la Calle-Martin, Barcelona, Spain |
| Cw*0221 | Scu00977 | EU499385 | Francisco de Paula Sanchez Gordo, Malaga, Spain |
| Cw*0617 | SJ280/32 | AM285029 | Gottfried Fischer, Vienna, Austria |
| Cw*0816 | FBCCB5992 | AB426906 | Yukari Kuroda, Fukuoka, Japan |
| Cw*120306 | LUMC-C46 | AM946387 | Jacqy DH Anholts, Leiden, The Netherlands |
| DRB1*150205 | P2976 | EU523122 | Lixing Yan, Hangzhou, China |
| MICA*056 | MYUL82208AN | AM944063 | Ann-Margaret Little, London, United Kingdom |
Table 2: Confirmatory Sequences
| Sequence | Cell Identification | Accession Number | Submitting Author |
|---|---|---|---|
| A*290201 | HSR131658 | AM944568 | Hien Tran, Heidelberg, Germany |
| B*0724 | BY00293 | EU555324 | Carolyn K Hurley, Washington DC, USA |
| B*1312 | Scu3556m | EU516353 | Francisco de Paula Sanchez Gordo, Malaga, Spain |
| B*1556 | BY00302 | EU555315 | Carolyn K Hurley, Washington DC, USA |
| B*270507 | LUMC-B49 | AM946390 | Jacqy DH Anholts, Leiden, The Netherlands |
| B*352001 | Scu03771m | EU516354 | Francisco de Paula Sanchez Gordo, Malaga, Spain |
| B*3537 | LUMC-B48 | AM946389 | Jacqy DH Anholts, Leiden, The Netherlands |
| B*391301 | C2035U | EU499386 | Francisco de Paula Sanchez Gordo, Malaga, Spain |
| B*3931 | LUMC-B3 | AM746506 | Jacqy DH Anholts, Leiden, The Netherlands |
| B*4080 | BY00276 | EU522474 | Carolyn K Hurley, Washington DC, USA |
| B*4421 | Scu03903 | EU499387 | Francisco de Paula Sanchez Gordo, Malaga, Spain |
| B*4450 | BY00294 | EU555323 | Carolyn K Hurley, Washington DC, USA |
| B*5140 | BY00289 | EU555327 | Carolyn K Hurley, Washington DC, USA |
| B*5714 | BY00275 | EU522475 | Carolyn K Hurley, Washington DC, USA |
| B*9541 | BY00277, BY00301 |
EU522473, EU555317 |
Carolyn K Hurley, Washington DC, USA |
| DRB1*1477 | CTJ-18807 | EU545181 | Lina Yan, Tianjin, China |
Table 3: Recently Published Sequences
| Sequence | References |
|---|---|
| B*4073 | (1) |
| B*4075 | (2) |
| B*5714 | (3) |
| B*9529 | (4) |
| B*9534 | (5) |
| G*010114 | (6) |
| DRB1*0465 | (7) |
References
- Kwon OJ, Kim J, Dirisala VR, Xiao R, Park C. A new HLA-B*40 variant, B*4073, identified by sequence-based typing in the Korean population. Tissue Antigens. 2008 71:250-1.
- Wang D, Zhang Z. Characterization of the novel allele HLA-B*4075. Tissue Antigens. 2008 71:251-2.
- Altermann WW, Grondkowski V, Reichert S, Seliger B, Schlaf G. A novel HLA-B*57 (B*5714) allele in a healthy male Caucasian individual. Tissue Antigens. 2008 71:253-4.
- Zhu FM, He J, Zhang W, Yan LX. Identification of a novel HLA-B*15 allele, B*9529, in the Chinese population. Tissue Antigens. 2008 71:254-5.
- Yan LX, Zhu FM, He JJ, Xu XG. A novel HLA-B*15 allele, B*9534, identified by sequence-based typing in the Chinese population. Tissue Antigens. 2008 71:256-7.
- Arnaiz-Villena A, Serrano-Vela JI, Reguera R, Perez-Saborido B, Moreno E, Moscoso J. A novel allele, HLA-G*010114, with a non-coding DNA base change in exon 2. Tissue Antigens. 2008 71:258-9.
- Witter K, Mautner J, Volgger A, Zahn R, Kauke T. A novel HLA-DRB1 allele, HLA-DRB1*0465, was identified in a Hodgkin's lymphoma cell line. Tissue Antigens. 2008 71:257-8.
