Nomenclature for Factors of the HLA System
October 2007
Compiled by Steven G. E. Marsh for the WHO Nomenclature Committee for Factors of the HLA System.
Published In:
- Tissue Antigens. 2007 71:183-4
- Human Immunology. 2007 69:66-7
- International Journal of Immunogenetics. 2007 35:171-2
The following sequences have been submitted to the Nomenclature Committee since the September 2007 nomenclature update and, following agreed policy, have been assigned official allele designations. Full details of all sequences will be published in a forthcoming report.
Below are listed the newly assigned sequences (Table 1) and confirmations of previously reported sequences (Table 2). The accession number of each sequence is given and these can be used to retrieve the sequence files from either the EMBL, GenBank or DDBJ data libraries. Although accession numbers have been assigned by the data libraries and most sequences are already available, there is still the possibility that an author may not yet have allowed the sequence to be released, in such a case you will have to contact the submitting author directly. Additional information pertaining to new sequences is often included in the publications describing these alleles, a listing of recent publications which describe new HLA sequences is given in Table 3.
All new and confirmatory sequences should now be submitted directly to the WHO Nomenclature Committee for Factors of the HLA System via the IMGT/HLA Database using the sequence submission tool provided. The IMGT/HLA Database may be accessed via the world wide web at : http://www.ebi.ac.uk/imgt/hla/.
Table 1: New Sequences
| Sequence | Cell identification | Accession number | Submitting Author |
|---|---|---|---|
| A*6607 | BJ061913 | EU140343 | Xiaoyan Shan, Beijing, China |
| A*680202 | BRABRI | EU189866 | Youri Serov, Indianapolis, USA |
| A*9235 | FBCCB5942 | AB355648 | Yukari Kuroda, Fukuoka, Japan |
| B*3584 | BY00263 | EU185515 | Carolyn K Hurley, Washington DC, USA |
| B*5715 | NT00744 | EU185513 | Carolyn K Hurley, Washington DC, USA |
| B*5716 | BS723143 | AM889027 | Jean-Marie Tiercy, Geneva, Switzerland |
| B*5816 | BY00260 | EU185518 | Carolyn K Hurley, Washington DC, USA |
| Cw*150204 | BJ049 | EU169936 | Na Liu, Beijing, China |
Table 2: Confirmatory Sequences
| Sequence | Cell Identification | Accession Number | Submitting Author |
|---|---|---|---|
| A*020605 | BY00264 | EU185509 | Carolyn K Hurley, Washington DC, USA |
| A*0254 | NT00746 | EU185511 | Carolyn K Hurley, Washington DC, USA |
| A*0284 | NT00747 | EU185510 | Carolyn K Hurley, Washington DC, USA |
| A*1119 | NT00745 | EU185512 | Carolyn K Hurley, Washington DC, USA |
| A*6836 | scu00946 | EU189033 | Francisco de Paula Sanchez Gordo, Malaga, Spain |
| B*0753 | NT00743 | EU185514 | Carolyn K Hurley, Washington DC, USA |
| B*130204 | MST987659354 | EU086373 | Reinhard Kelsch, Muenster, Germany |
| B*3706 | BY00259 | EU185519 | Carolyn K Hurley, Washington DC, USA |
| B*3811 | BY00261 | EU185517 | Carolyn K Hurley, Washington DC, USA |
| B*3920 | BY00258 | EU185520 | Carolyn K Hurley, Washington DC, USA |
| B*3939 | BY00262 | EU185516 | Carolyn K Hurley, Washington DC, USA |
| DPB1*110101 | H348 | AM887530 | Carlos Vilches, Madrid, Spain |
Table 3: Recently Published Sequences
| Sequence | References |
|---|---|
| A*260104 | (1) |
| A*7411 | (1) |
| B*3576 | (2) |
| Cw*010205 | (3) |
| Cw*0116 | (3) |
| Cw*0117 | (3) |
| Cw*0118 | (3) |
| Cw*0218 | (3) |
| Cw*030406 | (3) |
| Cw*030407 | (3) |
| Cw*0336 | (3) |
| Cw*0337 | (3) |
| Cw*033801 | (3) |
| Cw*0426 | (3) |
| Cw*0427 | (3) |
| Cw*0615 | (3) |
| Cw*0616N | (3) |
| Cw*0743 | (3) |
| Cw*0747 | (3) |
| Cw*0748 | (3) |
| Cw*0813 | (1) |
| Cw*1518 | (3) |
| Cw*1520 | (3) |
| Cw*1608 | (1) |
| Cw*1704 | (1) |
| Cw*1803 | (3) |
| DRB1*130502 | (1) |
| DQB1*0622 | (4) |
References
- Tu B, Mack SJ, Lazaro A, et al. HLA-A, -B, -C, -DRB1 allele and haplotype frequencies in an African American population. Tissue Antigens. 2007 69:73-85.
- Aubert V, Mayerat C, Lopez N, Pantaleo G. Sequence analysis of the novel HLA-B35 (B*3576) allele in an African individual. Tissue Antigens. 2007 70:439-41.
- Lebedeva TV, Ohashi M, Mastromarino SA, Alosco SM, Yu N. New HLA-C alleles identified in minority populations. Tissue Antigens. 2007 70:441-2.
- Chang Y, Fan TX, Santana Z, Day NK. Identification of a novel allele HLA-DQB1*0622. Tissue Antigens. 2007 70:442-4.
