Nomenclature for Factors of the HLA System
May 2007
Compiled by Steven G. E. Marsh for the WHO Nomenclature Committee for Factors of the HLA System.
Published In:
- Tissue Antigens. 2007 70:263-4
- Human Immunology. 2007 68:800-1
- International Journal of Immunogenetics. 2007 34:395-6
The following sequences have been submitted to the Nomenclature Committee since the April 2007 nomenclature update and, following agreed policy, have been assigned official allele designations. Full details of all sequences will be published in a forthcoming report.
Below are listed the newly assigned sequences (Table 1) and confirmations of previously reported sequences (Table 2). The accession number of each sequence is given and these can be used to retrieve the sequence files from either the EMBL, GenBank or DDBJ data libraries. Although accession numbers have been assigned by the data libraries and most sequences are already available, there is still the possibility that an author may not yet have allowed the sequence to be released, in such a case you will have to contact the submitting author directly. Additional information pertaining to new sequences is often included in the publications describing these alleles, a listing of recent publications which describe new HLA sequences is given in Table 3.
All new and confirmatory sequences should now be submitted directly to the WHO Nomenclature Committee for Factors of the HLA System via the IMGT/HLA Database using the sequence submission tool provided. The IMGT/HLA Database may be accessed via the world wide web at : http://www.ebi.ac.uk/imgt/hla/.
Table 1: New Sequences
| Sequence | Cell identification | Accession number | Submitting Author |
|---|---|---|---|
| A*0330 | Xian30109 | EF602747 | Mengli Liu, Xi'an, China |
| A*1132 | RA1283 | EF626806 | Min Yu, Chicago, USA |
| A*2316 | D24054 | AM493902 | Odile Avinens, Montpellier, France |
| A*2477 | BY00177 | EF591029 | Carolyn K Hurley, Washington, USA |
| A*2478 | 2004307seq | AB303946 | Hidetoshi Inoko, Isehara, Japan |
| A*3312 | BY00180 | EF591032 | Carolyn K Hurley, Washington, USA |
| A*9221 | SCCA-1 | EF534104 | Maggie Sprague, Seattle, USA |
| A*9221 | B8972 | EF632301 | Lixing Yan, Hangzhou, China |
| A*9222 | BY00178 | EF591030 | Carolyn K Hurley, Washington, USA |
| A*9223 | BY00176 | EF591028 | Carolyn K Hurley, Washington, USA |
| A*9224 | SCU00927 | EF579799 | Francisco de Paula Sanchez Gordo, Malaga, Spain |
| A*9225N | 06d05372 | AM711559 | Jacqy Anholts, Leiden, The Netherlands |
| A*9226 | 2001238PD | AB303947 | Hidetoshi Inoko, Isehara, Japan |
| B*070205 | D22669 | AM493903 | Odile Avinens, Montpellier, France |
| B*0757 | DJEGen | AM689936 | Anne Dormoy, Strasbourg, France |
| B*3577 | DCI-002 | EF620032 | Sallyanne Fossey, Nashville, USA |
| B*4817 | K13577, K13578 |
AB292739 | Etsuko Maruya, Kyoto, Japan |
| B*4818 | 2006032CB, 2006032mother |
AB303948 | Hidetoshi Inoko, Isehara, Japan |
| B*510203 | B16573 | EF611989 | Lixing Yan, Hangzhou, China |
| B*5713 | MHHN-414997 | AM712179 | Rainer Blasczyk, Hannover, Germany |
| B*9530 | RA1242 | EF622511 | Min Yu, Chicago, USA |
| B*9531 | 147351 | AM712922 | Francesca Poli, Milano, Italy |
| B*9532 | DCI-001 | EF620033 | Sallyanne Fossey, Nashville, USA |
| Cw*0119 | HanChineseA78 | EF189140 | Lin Ding, Guangzhou, China |
| G*010111 | HLAG005 | EF565823 | Erick Castelli, Ribeirao Preto, Sao Paulo, Brazil |
| G*010112 | JKKB-55 | EF218653 | KyuBum Kwack, Seoul, South Korea |
| G*010113 | JKKB-87 | EF218654 | KyuBum Kwack, Seoul, South Korea |
| G*0109 | JKKB-28 | EF218655 | KyuBum Kwack, Seoul, South Korea |
| DRB1*030105 | NT00735 | EF591034 | Carolyn K Hurley, Washington, USA |
| DQB1*0632 | B-200702759 | AM691798 | Florian Emmerich, Berlin, Germany |
| DQB1*0633 | D963.9 | EF622510 | Min Yu, Chicago, USA |
| DPB1*2102 | JERA34315AN | AM698036 | Ann-Margaret Little, London, United Kingdom |
Table 2: Confirmatory Sequences
| Sequence | Cell Identification | Accession Number | Submitting Author |
|---|---|---|---|
| A*0126 | NT00736 | EF591033 | Carolyn K Hurley, Washington, USA |
| A*2450 | BY00179 | EF591031 | Carolyn K Hurley, Washington, USA |
| A*2627 | BY00173 | EF591027 | Carolyn K Hurley, Washington, USA |
| A*3117 | Xian28632 | EF602748 | Mengli Liu, Xi'an, China |
Table 3: Recently Published Sequences
| Sequence | References |
|---|---|
| A*1129 | (1) |
| A*2471 | (2) |
| A*2632 | (3) |
| A*2634 | (4) |
| A*7403 | (5) |
| B*4070 | (6) |
| B*9523 | (7) |
| DRB1*0114 | (8) |
| DRB1*1376 | (2) |
| DRB1*1465 | (2) |
References
- Danzer M, Polin H, Hofer K, Gabriel C: HLA-A*1129, a new allele identified in a cord blood donor. Tissue Antigens 2007 69:611.
- Abdeen H, McErlean C, Moraes ME, et al.: Identification of three novel alleles of HLA-DRB1 and HLA-A in the Brazilian population. Tissue Antigens 2007 69:607-10.
- Kwon OJ, Lee JS, Oh JW, Nah SY, Jeong SM: Identification of a novel HLA-A*26 allele, HLA-A*2632, by sequence-based typing in the Korean population. Tissue Antigens 2007 69:612-3.
- Kwon OJ, Hong SA, Oh JW, Nah SY, Jeong SM: HLA-A*2634, a new allele identified by sequence-based typing in the Korean population. Tissue Antigens 2007 69:613-5.
- Canossi A, Del Beato T, Piazza A, et al.: Identification of the uncommon allele HLA-A*7403 in a Caucasian renal transplant cadaveric donor: extension of the exon 4 sequence. Tissue Antigens 2007 69:615-8.
- Jin WM, Du D, Liu X, Kong FH, Cai JP: Identification of a novel HLA-B allele HLA-B*4070 in a Chinese donor. Tissue Antigens 2007 69:618-9.
- Balas A, Sanchez-Gordo F, Garcia-Sanchez F, Prat I, Vicario JL: HLA-B*9523 increases the extremely high B*15-group polymorphism. Tissue Antigens 2007 69:620-1.
- Liu ML, Qi J, Zhang Y, Ye SH: Identification of a novel allele HLA-DRB1*0114 in two Chinese marrow donors by sequence-based typing. Tissue Antigens 2007 69:622.
