Nomenclature for Factors of the HLA System

November 2006

Compiled by Steven G. E. Marsh for the WHO Nomenclature Committee for Factors of the HLA System.

Published In:

The following sequences have been submitted to the Nomenclature Committee since the October 2006 nomenclature update and, following agreed policy, have been assigned official allele designations. Full details of all sequences will be published in a forthcoming report.

Below are listed the newly assigned sequences (Table 1) and confirmations of previously reported sequences (Table 2). The accession number of each sequence is given and these can be used to retrieve the sequence files from either the EMBL, GenBank or DDBJ data libraries. Although accession numbers have been assigned by the data libraries and most sequences are already available, there is still the possibility that an author may not yet have allowed the sequence to be released, in such a case you will have to contact the submitting author directly. Additional information pertaining to new sequences is often included in the publications describing these alleles, a listing of recent publications which describe new HLA sequences is given in Table 3.

All new and confirmatory sequences should now be submitted directly to the WHO Nomenclature Committee for Factors of the HLA System via the IMGT/HLA Database using the sequence submission tool provided. The IMGT/HLA Database may be accessed via the world wide web at :

Table 1: New Sequences

Sequence Cell identification Accession number Submitting Author
A*110106 B11798 EF092416 Lixing Yan, Hangzhou, China
A*2468 P1893 EF101926 Lixing Yan, Hangzhou, China
A*2634 2006071824 EF103189 Oh-Joong Kwon, Seoul, South Korea
A*2916 FP3924 AM410904 Wolfgang Altermann, Halle, Germany
A*3115 RA1139 EF123262 Min Yu, Chicago, USA
A*3214 VTIS138700 EF088205 Brian D. Tait, Melbourne, Australia
A*3309 D21977 AM410969 Wolfgang Altermann, Halle, Germany
A*9207 VTIS138774 EF088206 Brian D. Tait, Melbourne, Australia
A*9208 B13680 EF092417 Lixing Yan, Hangzhou, China
B*0751 VTIS146548 EF088202 Brian D. Tait, Melbourne, Australia
B*3570 P4881 AM410967 Wolfgang Altermann, Halle, Germany
B*3815 VTIS146619 EF088203 Brian D. Tait, Melbourne, Australia
B*4609 032094 EF121373 Jianping Li, Liaoning, China
B*480302 BY00137 EF078989 Carolyn K Hurley, Washington, USA
B*5410 K34690 EF081456 Marie Lin, Taipei, Taiwan
B*5814 VTIS143978 EF088201 Brian D. Tait, Melbourne, Australia
Cw*0333 M268N AM408917 Gregory Minevich, New York, USA
Cw*0334 TBC62026 AB274957 Masahiro Satake, Tokyo, Japan
Cw*0614 VTIS133092 EF088199 Brian D. Tait, Melbourne, Australia
Cw*0744 VTIS135203 EF088200 Brian D. Tait, Melbourne, Australia
Cw*0745 TBC62255 AB274958 Masahiro Satake, Tokyo, Japan
DRB1*040303 173171 AM409261 Heather Dunckley, Sydney, Australia
DRB1*0462 BY00139 EF078990 Carolyn K Hurley, Washington, USA
DRB1*0712 HABH6660AN,
AM411359 Ann-Margaret Little, London, United Kingdom
DRB1*1158 100763 AM409260 Heather Dunckley, Sydney, Australia
DRB1*1159 169843 AM409259 Heather Dunckley, Sydney, Australia
DRB1*1160 174307 AM409258 Heather Dunckley, Sydney, Australia
DRB1*140503 2006071961 EF103190 Oh-Joong Kwon, Seoul, South Korea
DRB1*1464 BY00136 EF078986 Carolyn K Hurley, Washington, USA
DRB1*150204 99593 AM409257 Heather Dunckley, Sydney, Australia
DRB1*150204 NT00683 EF078988 Carolyn K Hurley, Washington, USA
DQB1*030204 106329 AM409256 Heather Dunckley, Sydney, Australia
DPB1*2002 MITH93933AN AM408787 Ann-Margaret Little, London, United Kingdom

Table 2: Confirmatory Sequences

Sequence Cell Identification Accession Number Submitting Author References
A*02010102L PER (II.2) AM286552 Anne Dormoy, Strasbourg, France (1)
A*3112 VTIS144743 EF088204 Brian D. Tait, Melbourne, Australia  
A*3408 NT00684 EF078984 Carolyn K Hurley, Washington, USA  
B*2736 SZ-6 DQ915176 Zhen Li, Shenzhen, China  
B*5106 TBC60704 AB274956 Masahiro Satake, Tokyo, Japan  
DRB1*0319 133983 AM409244 Heather Dunckley, Sydney, Australia  
DRB1*040503 140383 AM409248 Heather Dunckley, Sydney, Australia  
DRB1*0412 132935 AM409255 Heather Dunckley, Sydney, Australia  
DRB1*0433 177927 AM409254 Heather Dunckley, Sydney, Australia  
DRB1*0436 175586 AM409253 Heather Dunckley, Sydney, Australia  
DRB1*0439 166438 AM409252 Heather Dunckley, Sydney, Australia  
DRB1*0440 101330 AM409251 Heather Dunckley, Sydney, Australia  
DRB1*0815 161024 AM409250 Heather Dunckley, Sydney, Australia  
DRB1*110101 182590 AM409247 Heather Dunckley, Sydney, Australia  
DRB1*110102 159548 AM409246 Heather Dunckley, Sydney, Australia  
DRB1*1105 163635 AM409245 Heather Dunckley, Sydney, Australia  
DRB1*1321 186105 AM409249 Heather Dunckley, Sydney, Australia  
DRB1*1350 BY00138 EF078987 Carolyn K Hurley, Washington, USA  
DRB1*1430 87816 U95115 Heather Dunckley, Sydney, Australia  
DRB1*150106 BY00140 EF078985 Carolyn K Hurley, Washington, USA  

Table 3: Recently Published Sequences

Sequence References
A*110104 (2)
B*070503 (3)
B*3565Q (4)
Cw*031102 (5)
DQA1*010204 (6)
DQA1*0509 (6)
DQB1*060403 (7)


  1. Perrier P, Dormoy A, Andre-Botte C, Froelich N: HLA-A*02010102L: a laborious assignment. Tissue Antigens 2006 68:442-5.
  2. Sun Y, Liu S, Luo Y, Liang F, Xi Y: Identification and frequency of a novel HLA-A allele, A*110104. Tissue Antigens 2006 68:453-4.
  3. Li JP, Chen Y, Zhang X, Li XF, Liu XZ: A new HLA-B*07 allele, B*070503, identified in a Chinese bone marrow donor. Tissue Antigens 2006 68:454-5.
  4. Elsner HA, Horn PA, Schoenemann C, Altermann WW, Blasczyk R: Aberrant expression of HLA-B*3565Q is associated with a disrupted disulfide bond. Immunogenetics 2006 58:929-31.
  5. Hammond L, Street J, Johnson J, Pepperall J, Darke C: A new HLA-Cw*03 variant - Cw*031102. Tissue Antigens 2006 68:455-6.
  6. Voorter CE, van den Berg-Loonen EM: Sequence-based typing of the complete coding sequence of DQA1 and phenotype frequencies in the Dutch Caucasian population. Hum Immunol 2006 67:756-63.
  7. Nolan K, Schiller J, Ghosh S, Magnuson V: Identification of a novel HLA-DQB1 allele, DQB1*060403, by sequence-based typing. Tissue Antigens 2006 68:456-7.