Nomenclature for Factors of the HLA System

July 2006

Compiled by Steven G. E. Marsh for the WHO Nomenclature Committee for Factors of the HLA System.

Published In:

The following sequences have been submitted to the Nomenclature Committee since the June 2006 nomenclature update and, following agreed policy, have been assigned official allele designations. Full details of all sequences will be published in a forthcoming report.

Below are listed the newly assigned sequences (Table 1) and confirmations of previously reported sequences (Table 2). The accession number of each sequence is given and these can be used to retrieve the sequence files from either the EMBL, GenBank or DDBJ data libraries. Although accession numbers have been assigned by the data libraries and most sequences are already available, there is still the possibility that an author may not yet have allowed the sequence to be released, in such a case you will have to contact the submitting author directly. Additional information pertaining to new sequences is often included in the publications describing these alleles, a listing of recent publications which describe new HLA sequences is given in Table 3.

All new and confirmatory sequences should now be submitted directly to the WHO Nomenclature Committee for Factors of the HLA System via the IMGT/HLA Database using the sequence submission tool provided. The IMGT/HLA Database may be accessed via the world wide web at :

Table 1: New Sequences

Sequence Cell identification Accession number Submitting Author
A*2632 2006051203 DQ780570 Oh-Joong Kwon, Seoul, South Korea
A*3212 MHHN-154465 AM282701 Rainer Blasczyk, Hannover, Germany
A*6835 A016699 DQ788799 Wei Dong, Philadelphia, USA
B*1317 BY00124 DQ832588 Carolyn Hurley, Washington, USA
B*5143 73626 DQ834251 Mary Sue Leffell, Baltimore, USA
B*9517 BY000123 DQ832587 Carolyn Hurley, Washington, USA
Cw*0330 MT-10-06 DQ780571 Oh-Joong Kwon, Seoul, South Korea
Cw*0330 MT-10-06 DQ784564 Min Yu, Chicago, USA
Cw*0423 CB4737 DQ788797 Wei Dong, Philadelphia, USA
Cw*0424 A016658 DQ788798 Wei Dong, Philadelphia, USA
Cw*0741 VEGJC1 AM237285 Anne Dormoy, Strasbourg, France
DRB1*1611 K9505074 DQ837166 Marie Lin, Taipei, Taiwan
DQB1*030203 OLI AM286421 Xavier Lafarge, Bordeaux, France

Table 2: Confirmatory Sequences

Sequence Cell Identification Accession Number Submitting Author
B*2736 SAMPLE-7319 DQ840458 Lina Yan, Tianjin, China
B*5136 BY00122 DQ832586 Carolyn Hurley, Washington, USA
B*5614 BY00125 DQ832583 Carolyn Hurley, Washington, USA

Table 3: Recently Published Sequences

Sequence References
A*0119 (1)
A*0319 (2)
B*3564 (3)
B*3812 (4)
B*4904 (5)
Cw*140204 (6)
DRB1*1213 (7)
DRB1*1456 (8)


  1. Schlaf G, Wahle A, Seliger B, Altermann WW: A novel HLA-A*0119 allele of a Caucasian family containing a mutation in a highly conserved region. Int J Immunogenet 2006 33:247-8.
  2. Jeong SM, Park SY, Kim JH, Kwon OJ, Nah SY: Identification of a novel HLA-A*03 allele, HLA-A*0319, by sequence-based typing. Tissue Antigens 2006 68:87-8.
  3. Hwang SH, Lim YS, Kwon OJ, Heo YS, Oh HB: Structural aspects of the B*3564 molecule, a novel HLA-B*35 allele identified by sequence-based typing. Tissue Antigens 2006 68:90-1.
  4. Aureli A, Piancatelli D, Ozzella G, Liberatore G, Piazza A, Adorno D: B*3812: a new HLA-B38 variant identified by sequence-based typing. Tissue Antigens 2006 68:91-3.
  5. Nesci S, Buffi O, Iliescu A, Scalari P, Luchetti MM: HLA-B*4904, a new allele identified in two unrelated individuals from the same Italian region. Tissue Antigens 2006 68:89-90.
  6. Piancatelli D, Del Beato T, Aureli A, Papola F, Adorno D: A new HLA-CW*14 allele, Cw*140204, identified by allele-specific DNA amplification and sequencing. Tissue Antigens 2006 68:93-5.
  7. Jeong SM, Lee MN, Kim JH, Kwon OJ, Nah SY: A novel HLA-DRB1*12 allele, HLA-DRB1*1213, identified by sequence-based typing. Tissue Antigens 2006 68:95-7.
  8. Baek JY, Yun HS, Hur SS, Kwon OJ, Kwack K: Identification of a novel HLA-DRB1*14 allele, DRB1*1456, in the cord blood of a Korean baby. Tissue Antigens 2006 68:97-8.