Nomenclature for Factors of the HLA System
February 2006
Compiled by Steven G. E. Marsh for the WHO Nomenclature Committee for Factors of the HLA System.
Published In:
- Tissue Antigens. 2006 67:440-2
- Human Immunology. 2006 67:554-6
- International Journal of Immunogenetics. 2006 33:227-8
The following sequences have been submitted to the Nomenclature Committee since the January 2006 nomenclature update and, following agreed policy, have been assigned official allele designations. Full details of all sequences will be published in a forthcoming report.
Below are listed the newly assigned sequences (Table 1) and confirmations of previously reported sequences (Table 2). The accession number of each sequence is given and these can be used to retrieve the sequence files from either the EMBL, GenBank or DDBJ data libraries. Although accession numbers have been assigned by the data libraries and most sequences are already available, there is still the possibility that an author may not yet have allowed the sequence to be released, in such a case you will have to contact the submitting author directly. Additional information pertaining to new sequences is often included in the publications describing these alleles, a listing of recent publications which describe new HLA sequences is given in Table 3.
All new and confirmatory sequences should now be submitted directly to the WHO Nomenclature Committee for Factors of the HLA System via the IMGT/HLA Database using the sequence submission tool provided. The IMGT/HLA Database may be accessed via the world wide web at : http://www.ebi.ac.uk/imgt/hla/.
Table 1: New Sequences
| Sequence | Cell Identification | Accession Number | Submitting Author |
|---|---|---|---|
| A*0293 | VTIS116760 | DQ400528, DQ400529 |
Brian D. Tait, Melbourne, Australia |
| A*0294N | VTIS138070 | DQ400512, DQ400513 |
Brian D. Tait, Melbourne, Australia |
| A*0295 | VTIS119848 | AY505488, AY505489 |
Brian D. Tait, Melbourne, Australia |
| A*1125 | PABR19129AN | AM183562 | Ann-Margaret Little, London, United Kingdom |
| A*1126 | KN9409963 | DQ343835 | Marie Lin, Taipei, Taiwan |
| A*2461 | DUB330 | AJ616915 | Ciaran Dunne, Dublin, Eire |
| A*2462 | K05528 | AB249885 | Etsuko Maruya, Kyoto, Japan |
| A*2628 | VTIS129380 | DQ400520, DQ400521 |
Brian D. Tait, Melbourne, Australia |
| A*6606 | VTIS132513 | DQ400518, DQ400519 |
Brian D. Tait, Melbourne, Australia |
| A*6832 | VTIS12881 | DQ400522, DQ400523 |
Brian D. Tait, Melbourne, Australia |
| B*0747 | 151235 | DQ343758 | Kaimo Hirv, Ulm, Germany |
| B*2734 | 158567 | AM230596 | Klaus Witter, München, Germany |
| B*3566 | BY00081 | DQ401172, DQ401173 |
Carolyn K. Hurley, Washington, USA |
| B*3711 | NT00649 | DQ401184, DQ401185 |
Carolyn K. Hurley, Washington, USA |
| B*380102 | NT00650 | DQ401178, DQ401179 |
Carolyn K. Hurley, Washington, USA |
| B*3941 | TBC58854 | AB248098 | Masahiro Satake, Tokyo, Japan |
| B*4063 | TBC56240 | AB232526 | Masahiro Satake, Tokyo, Japan |
| B*4064 | VTIS121219 | DQ400516, DQ400517 |
Brian D. Tait, Melbourne, Australia |
| B*4447 | 259133 | DQ343759 | Kaimo Hirv, Ulm, Germany |
| B*5141N | TBC58362 | AB247569 | Masahiro Satake, Tokyo, Japan |
| B*5209 | 160039 | AM181591 | Klaus Witter, München, Germany |
| B*9511N | TBC58168 | AB247568 | Masahiro Satake, Tokyo, Japan |
| B*9512 | Chendu6060 | DQ364132 | Tongmao Zhao, Bethesda, USA |
| B*9513 | VTIS139151 | DQ400510, DQ400511 |
Brian D. Tait, Melbourne, Australia |
| Cw*0112 | VTIS121253 | DQ400524, DQ400525 |
Brian D. Tait, Melbourne, Australia |
| Cw*0113 | NT00651 | DQ401182, DQ401183 |
Carolyn K. Hurley, Washington, USA |
| Cw*0324 | VTIS87520 | DQ400530, DQ400531 |
Brian D. Tait, Melbourne, Australia |
| Cw*0737 | TBC58855 | AB248242 | Masahiro Satake, Tokyo, Japan |
| Cw*0738 | VTIS137941 | DQ400514, DQ400515 |
Brian D. Tait, Melbourne, Australia |
| E*01010103 | LKT3 | AB088094 | Hidetoshi Inoko, Isehara, Japan |
| DRB1*0457 | TBC58426 | AB248283 | Masahiro Satake, Tokyo, Japan |
| DRB1*1155 | 16068 | AM231063 | Klaus Witter, München, Germany |
| DRB1*1214 | KS9407622 | DQ343834 | Marie Lin, Taipei, Taiwan |
| DQB1*0628 | 158308 | AM181332 | Klaus Witter, München, Germany |
| DPB1*1702 | GZ7272 | DQ206450 | Xue Qing Yu, Guangzhou, China |
Table 2: Confirmatory Sequences
| Sequence | Cell Identification | Accession Number | Submitting Author |
|---|---|---|---|
| A*3010 | VTIS129599 | DQ400532, DQ400533 |
Brian D. Tait, Melbourne, Australia |
| B*3931 | VTIS125412 | AY829219, AY829220 |
Brian D. Tait, Melbourne, Australia |
| B*4050 | VTIS125430 | AY829221, AY829222 |
Brian D. Tait, Melbourne, Australia |
| B*5615 | NT00648 | DQ401176, DQ401177 |
Carolyn K. Hurley, Washington, USA |
| Cw*0717 | NT00646 | DQ401174, DQ401175 |
Carolyn K. Hurley, Washington, USA |
| Cw*1216 | NT00647 | DQ401180, DQ401081 |
Carolyn K. Hurley, Washington, USA |
Table 3: Recently Published Sequences
| Sequence | References |
|---|---|
| A*0287 | (1) |
| A*1115 | (2) |
| A*2313 | (3) |
| A*2911 | (4) |
| A*3308 | (5) |
| A*680104 | (6) |
| A*6827 | (4) |
| B*0743 | (7) |
| B*1586 | (8) |
| B*3710 | (9) |
| B*4905 | (10) |
| Cw*030404 | (11) |
| Cw*1217 | (11) |
| DRB1*0826 | (12) |
| DRB1*0904 | (13) |
| DRB1*1152 | (14) |
| DQB1*0627 | (12) |
References
- Yun HS, Baek JY, Hur SS, Kwon OJ, Kwack K: Identification of a novel HLA-A*02 allele, A*0287, in the cord blood of a Korean baby. Tissue Antigens 2006 67:167-8.
- Bendukidze N, Day S, Street J, et al.: Identification of a novel HLA-A allele (A*1115) in the UK National External Quality Assessment Schemes for Histocompatibility and Immunogenetics' Educational Cell Exchange. Tissue Antigens 2006 67:153-6.
- Horn PA, Verboom M, Blasczyk R: HLA-A*2313 is closest to A*2301 but is likely to stimulate T cells when mismatched. Tissue Antigens 2006 67:166-7.
- Alkharsah KR, Dedicoat M, Deluca DS, Schulz TF, Blasczyk R: Identification of two new HLA-A variants, HLA-A*2911 and HLA-A*6827. Tissue Antigens 2006 67:170-2.
- Yan LX, Zhu FM, Lv QF, Zhang W, He J: Identification of a new allele, HLA-A*3308, in the Chinese population. Tissue Antigens 2006 67:168-9.
- Heymann GA, Lassahn A, Schonemann C, Salama A: A novel HLA-A*680104 variant. Tissue Antigens 2006 67:169-70.
- Cha YY, Baek JY, Heo YS, Kwack K, Kwon OJ: A novel identification of HLA-B*07 allele, HLA-B*0743, in the Korean population. Tissue Antigens 2006 67:172-3.
- Yang Y, Aubrey MT, Zhang G, Ji Y, Freed BM: HLA-B*1586 is a novel, hybrid HLA-B15/B22 allele with unique serology and haplotypic association. Tissue Antigens 2006 67:176-7.
- Frison S, Longhi E, Espadas de Arias A, Andreini E, Poli F, Scalamogna M: Characterization of the novel allele HLA-B*3710. Tissue Antigens 2006 67:173-4.
- Andreini E, Longhi E, Frison S, Bontempelli M, Castellani L, Poli F: Identification of HLA-B*4905 in a Caucasian family. Tissue Antigens 2006 67:174-6.
- S WP, S HC, E CR: Identification of two novel HLA-C alleles, HLA-Cw*1217 and HLA-Cw*030404, in Singapore Chinese. Tissue Antigens 2006 67:177-9.
- Brixner V, Mosebach M, Schmidt M, et al.: HLA-DRB1*0826 and HLA-DQB1*0627, two novel class II alleles identified in blood stem cell donors of Caucasian origin. Tissue Antigens 2006 67:160-2.
- Song CH, Baek JY, Heo YS, Kwack K, Kwon OJ: Identification of a novel HLA-DRB1*09 allele, DRB1*0904, in the Korean population, by sequence-based typing. Tissue Antigens 2006 67:179-80.
- Ozzella G, Monaco PI, Tessitore A, Piazza A, Piancatelli D, Adorno D: Identification of a novel HLA-DRB1*11 allele: DRB1*1152. Tissue Antigens 2006 67:180-2.
