Nomenclature for Factors of the HLA System

September 2005

Compiled by Steven G. E. Marsh for the WHO Nomenclature Committee for Factors of the HLA System.

Published In:

The following sequences have been submitted to the Nomenclature Committee since the August 2005 nomenclature update and, following agreed policy, have been assigned official allele designations. Full details of all sequences will be published in a forthcoming report.

Below are listed the newly assigned sequences, confirmations of previously reported sequences and some sequences which are corrections of those originally reported. The accession number of each sequence is given and these can be used to retrieve the sequence files from either the EMBL, GenBank or DDBJ data libraries. Although accession numbers have been assigned by the data libraries and most sequences are already available, there is still the possibility that an author may not yet have allowed the sequence to be released, in such a case you will have to contact the submitting author directly.

All new and confirmatory sequences should now be submitted directly to the WHO Nomenclature Committee for Factors of the HLA System via the IMGT/HLA Database using the sequence submission tool provided. The IMGT/HLA Database may be accessed via the world wide web at : http://www.ebi.ac.uk/imgt/hla/.

Table 1: New Sequences


Sequence Cell Identification Accession Number Submitting Author
A*0288N UKE-J-DD AM076769 Thomas Binder, Hamburg, Germany
A*0289 CTM5689590 DQ188810 Jose L. Vicario, Madrid, Spain
A*2314 20020885CB AB234291 Hidetoshi Inoko, Kanagawa, Japan
A*240209 2004150JCBN AB234290 Hidetoshi Inoko, Kanagawa, Japan
A*240210 CTM2097181 DQ188808 Jose L. Vicario, Madrid, Spain
A*3113 HZ7146 DQ206619,

DQ206620
,

DQ2066621
Lixing Yan, Hangzhou, China
A*6605 20020721CB AB213609 Hidetoshi Inoko, Kanagawa, Japan
B*0744 CTM9748540 DQ196429 Jose L. Vicario, Madrid, Spain
B*4446 5089 DQ185396 Jianping Li, Liaoning, China
B*4608 HZ7551 DQ177521,
DQ177522,
DQ177523
Lixing Yan, Hangzhou, China
B*4905 147554 AM076839 Francesca Poli, Milano, Italy
B*5311 CTM7097881 DQ188812 Jose L. Vicario, Madrid, Spain
B*550104 33137 AM075814 Laura Hammond, Pontyclun, U.K.
Cw*030404 CM975 DQ200948,
DQ200949
Ee-Chee Ren, Singapore, Singapore
Cw*0320N CTM5745799 DQ188807 Jose L. Vicario, Madrid, Spain
Cw*0732N CTM8689384 DQ188806 Jose L. Vicario, Madrid, Spain
Cw*1217 CM924 DQ206990,
DQ206991
Ee-Chee Ren, Singapore, Singapore
DRB1*1453 BISLo AM084908 Anne Dormoy, Strasbourg, France
DRB1*1610 HZ8028 DQ192647 Lixing Yan, Hangzhou, China
DQA1*010203 BM3171 DQ178400,
DQ178401,
DQ178402,
DQ178403
Kyung Wha Lee, Anyang City, South Korea
DQA1*0506 BM3114 DQ178404,
DQ178405,
DQ178406,
DQ178407
Kyung Wha Lee, Anyang City, South Korea
DQA1*0507 BM3189 DQ178408,
DQ178409,
DQ178410,
DQ178411
Kyung Wha Lee, Anyang City, South Korea
DQA1*0508 BM3146 DQ178412,
DQ178413,
DQ178414,
DQ178415
Kyung Wha Lee, Anyang City, South Korea
MICA*052 D15 AY748458,
AY748459,
AY748460,
AY748461
Virginia Mas, Barcelona, Spain
MICA*053 U044 AJ871399 Martin C. N. M. Barnardo, Oxford, U.K.

Table 2: Confirmatory Sequences


Sequence Cell Identification Accession Number Submitting Author
A*0253N NS0657 AB233410 Tomoko Kinoshita, Nishinomiya-City, Japan
A*0277 CTM1689326 DQ188811 Jose L. Vicario, Madrid, Spain
A*24020102L CTM6689449 DQ188809 Jose L. Vicario, Madrid, Spain
B*3541 Halmar AM076816 Paul Dunn, Auckland, New Zealand
B*5706 CTM2988653 DQ191316 Jose L. Vicario, Madrid, Spain
DPB1*0901 RA54 DQ148298,
DQ148299,
DQ148300,
DQ148301
Rajni Rani, New Delhi, India

Table 3: Recently Published Sequences


Sequence References
A*027401 (1)
A*1120 (2)
A*3111 (3)
B*0740 (4)
B*4051 (5)
B*5518 (6)
DRB1*0830 (7)
DRB1*1364 (5)

References

  1. Piancatelli D, Beato TD, Papola F, et al.: Identification of a novel HLA-A*02 allele, A*027401*. Tissue Antigens 2005 66:138-40.
  2. Kwon OJ, Hwang SH, Heo YS, Hur SS, Lee MN, Oh HB: Novel HLA-A*11 allele, A*1120, identified by sequence-based typing. Tissue Antigens 2005 66:141-4.
  3. Hwang SH, Oh HB, Hur SS, Lee MN, Hong SA, Kwon OJ: Novel HLA-A*31 allele, A*3111 identified by sequence-based typing. Tissue Antigens 2005 66:145-7.
  4. Wang CY, Pan Q, Xue M, et al.: Identification of an HLA-B*07 allele variant (B*0740) in the Chinese Han population. Tissue Antigens 2005 66:148-50.
  5. Czachurski D, Scollo A, Skambraks A, et al.: Description and characterization of two new HLA alleles, B*4051 and DRB1*1364, identified by sequence-based typing. Tissue Antigens 2005 66:151-5.
  6. Lebedeva TV, Huang A, Ohashi M, et al.: The recombinant HLA-B*5518 allele supports the evidence of conserved haplotype association of rare alleles. Tissue Antigens 2005 66:156-9.
  7. Hoppe B, Heymann GA, Kiesewetter H, Salama A: Identification and characterization of a novel HLA-DRB1 allele, DRB1*0830*. Tissue Antigens 2005 66:160-2.