Nomenclature for Factors of the HLA System

August 2005

Compiled by Steven G. E. Marsh for the WHO Nomenclature Committee for Factors of the HLA System.

Published In:

The following sequences have been submitted to the Nomenclature Committee since the July 2005 nomenclature update and, following agreed policy, have been assigned official allele designations. Full details of all sequences will be published in a forthcoming report.

Below are listed the newly assigned sequences, confirmations of previously reported sequences and some sequences which are corrections of those originally reported. The accession number of each sequence is given and these can be used to retrieve the sequence files from either the EMBL, GenBank or DDBJ data libraries. Although accession numbers have been assigned by the data libraries and most sequences are already available, there is still the possibility that an author may not yet have allowed the sequence to be released, in such a case you will have to contact the submitting author directly.

All new and confirmatory sequences should now be submitted directly to the WHO Nomenclature Committee for Factors of the HLA System via the IMGT/HLA Database using the sequence submission tool provided. The IMGT/HLA Database may be accessed via the world wide web at : http://www.ebi.ac.uk/imgt/hla/.

Table 1: New Sequences


Sequence Cell Identification Accession Number Submitting Author
A*0287 2005061422 DQ139310,
DQ139311		 Oh-Joong Kwon, Seoul, South Korea
A*0319 2005062436 DQ139312,
DQ139313		 Oh-Joong Kwon, Seoul, South Korea
A*0320 CHRJM AM056023 Anne Dormoy, Strasbourg, France
A*2313 MHHZ-00017616 AM072344 Rainer Blasczyk, Hannover, Germany
A*680104 2005-1737 AM062639 Guido A. Heymann, Berlin, Germany
B*070503 56 DQ162803 Jianping Li, Liaoning, China
B*3935 BY00075 DQ167213,
DQ167214		 Carolyn K. Hurley, Washington, U.S.A.
B*550103 TUWI3303661AN AM055594 Ann-Margaret Little, London, U.K.
B*5520 56352,
NT00572		 AY504809,
AY504810,
DQ120786,
DQ120787		 Carolyn K. Hurley, Washington, U.S.A.
B*9505 NT00611 DQ167211,
DQ167212		 Carolyn K. Hurley, Washington, U.S.A.
B*9506 DNA-0206 AM075816 Mats Bengtsson, Uppsala, Sweden
DRB1*1518 DORFra AM056024 Anne Dormoy, Strasbourg, France
DQB1*0317 K32633,
K32633F		 DQ114427 Marie Lin, Taipei, Taiwan

Table 2: Confirmatory Sequences


Sequence Cell Identification Accession Number Submitting Author
A*260102 BY00068 DQ123855,
DQ123856		 Carolyn K. Hurley, Washington, U.S.A.
A*6813 34687 AM072964 Thibaut Gervais, Brussels, Belgium
B*5811 87861 DQ140400 Mary Sue Leffell, Baltimore, U.S.A.

Table 3: Recently Published Sequences


Sequence References
A*2451 (1)
A*3012 (2)
B*0739 (3)
B*270505 (2)
B*3541 (2)
B*5517 (4)
Cw*0716 (2)
Cw*080102 (5)
Cw*1210 (5)
DPB1*0302 (6)
DRB1*111902 (7)
DRB1*1366 (8)

References

  1. Li JP, Liu XZ, Gao HF, et al.: Identification of a novel HLA-A allele HLA-A*2451 in a Chinese donor. Tissue Antigens 200566:54-5.
  2. Alonso-Nieto M, Garcia-Sanchez F, Lillo R, et al.: Four new HLA class I alleles in Cauacasoids. Tissue Antigens 2005 66:51-3.
  3. Horn PA, Blasczyk R: The variation of the novel allele HLA-B*0739 suggests low alloreactivity when mismatched with HLA-B*0702. Tissue Antigens 2005 66:56-7.
  4. Witter K, Volgger A, Zahn R, Scholz S, Sala M, Albert ED: Bone marrow donor routine HLA typing identified a novel B*55 allele, B*5517, confirmed by allele-specific DNA cycle sequencing. Tissue Antigens 2005 66:58-60.
  5. Chu CC, Lee HL, Chen ZX, Lin M: A newly identified HLA-C allele: Cw*1210, and confirmation of HLA-Cw*080102. Tissue Antigens 2005 66:61-3.
  6. Sheldon MH, Azzaro MP, Sayer D, Bunce M, Sortino G: Identification of a new allele in a Sicilian individual: HLA-DPB1*0302. Tissue Antigens 2005 66:64-6.
  7. Li D, Gao HF, Liu X, et al.: Identification of a novel HLA-DRB1 allele (HLA-DRB1*111902*). Tissue Antigens 2005 66:67-8.
  8. Milia S, Lai S, Valentini T, et al.: Identification of a new allele, HLA-DRB1*1366*. Tissue Antigens 2005 66:69-71.