Nomenclature for Factors of the HLA System

Juky 2005

Compiled by Steven G. E. Marsh for the WHO Nomenclature Committee for Factors of the HLA System.

Published In:

The following sequences have been submitted to the Nomenclature Committee since the June 2005 nomenclature update and, following agreed policy, have been assigned official allele designations. Full details of all sequences will be published in a forthcoming report.

Below are listed the newly assigned sequences, confirmations of previously reported sequences and some sequences which are corrections of those originally reported. The accession number of each sequence is given and these can be used to retrieve the sequence files from either the EMBL, GenBank or DDBJ data libraries. Although accession numbers have been assigned by the data libraries and most sequences are already available, there is still the possibility that an author may not yet have allowed the sequence to be released, in such a case you will have to contact the submitting author directly.

All new and confirmatory sequences should now be submitted directly to the WHO Nomenclature Committee for Factors of the HLA System via the IMGT/HLA Database using the sequence submission tool provided. The IMGT/HLA Database may be accessed via the world wide web at : http://ww.ebi.ac.uk/imgt/hla/.

Table 1: New Sequences


Sequence Cell Identification Accession Number Submitting Author
A*0116N 42989 AM040978 Laura Hammond, Pontyclun, U.K.
A*020112 Z-00016417 AM050155 Rainer Blasczyk, Hannover, Germany
A*0318 MHHZ-00008720 AJ871405 Rainer Blasczyk, Hannover, Germany
A*240208 BY00060 DQ105564,
DQ105565		 Carolyn K. Hurley, Washington, U.S.A.
B*070502 Z-00015026 AM050156 Rainer Blasczyk, Hannover, Germany
B*0826 NT00570 DQ120784,
DQ120785		 Carolyn K. Hurley, Washington, U.S.A.
B*130203 MIPO321144AN AM000052 Ann-Margaret Little, London, U.K.
B*1821 Z-00018417 AM050157 Rainer Blasczyk, Hannover, Germany
B*2731 NT00589 DQ105581,
DQ105582		 Carolyn K. Hurley, Washington, U.S.A.
B*350105 MHH0303078 AM050159 Rainer Blasczyk, Hannover, Germany
B*4108 NT00564 DQ105579,
DQ105580		 Carolyn K. Hurley, Washington, U.S.A.
B*4207 MHH0308010 AM040197 Rainer Blasczyk, Hannover, Germany
B*4444 NT00607 DQ120788,
DQ120789		 Carolyn K. Hurley, Washington, U.S.A.
B*4445 Z-00018416 AM050158 Rainer Blasczyk, Hannover, Germany
B*4606 BY00064 DQ105575,
DQ105576,
DQ105577,
DQ105578		 Carolyn K. Hurley, Washington, U.S.A.
B*4607N BY00062 DQ105569,
DQ105570,
DQ105571		 Carolyn K. Hurley, Washington, U.S.A.
B*5139 BY00063 DQ105572,
DQ105573,
DQ105574		 Carolyn K. Hurley, Washington, U.S.A.
B*5710 NT00604 DQ120782,
DQ120783		 Carolyn K. Hurley, Washington, U.S.A.
Cw*050103 009600958 AF538310,
AF541997		 Thomas M. Williams, Albuquerque, U.S.A.
Cw*070104 012410767 AF538309,
AF541998		 Jin Wu, Albuquerque, U.S.A.
Cw*0813 NT00600 DQ105583,
DQ105584		 Carolyn K. Hurley, Washington, U.S.A.
Cw*1216 87864 DQ112223 Mary Sue Leffell, Baltimore, U.S.A.
Cw*1608 NT00599 DQ105585,
DQ105586		 Carolyn K. Hurley, Washington, U.S.A.
Cw*1704 NT00602 DQ135947,
DQ135948		 Carolyn K. Hurley, Washington, U.S.A.
F*01010102 595 AF523295 Daniel E. Geraghty, Seattle, U.S.A.
F*01010103 JHUAA0394,
JHUAA0396,
IHW01141,
HAN19-01,
HAN19-04		 AY645742,
AY645750,
AY645758		 Daniel E. Geraghty, Seattle, U.S.A.
F*01010104 IHW01175,
IHW01184,
HAN19-01,
HAN19-05		 AY645753,
AY645757		 Daniel E. Geraghty, Seattle, U.S.A.
F*01010105 HAN19-02,
HAN19-04,
HAN19-05		 AY645759 Daniel E. Geraghty, Seattle, U.S.A.
F*01010106 JHUAA0528 AY645746 Daniel E. Geraghty, Seattle, U.S.A.
F*01010107 IHW01141,
IHW01152		 AY645751 Daniel E. Geraghty, Seattle, U.S.A.
F*01010202 JHUAA0394 AY645745 Daniel E. Geraghty, Seattle, U.S.A.
F*01010203 IHW01175,
IHW01181		 AY645756 Daniel E. Geraghty, Seattle, U.S.A.
F*01010204 1471 AF523294 Daniel E. Geraghty, Seattle, U.S.A.
F*01010205 JHUAA0393,
JHUAA0396,
JHUAA0527		 AY645744,
AY645749		 Daniel E. Geraghty, Seattle, U.S.A.
F*01010301 LKT3 AB088082 Hidetoshi Inoko, Isehara, Kanagawa, Japan
F*01010301 LBF,
STEINLIN,
BM15		 AF523285,
AF523286,
AF523289		 Daniel E. Geraghty, Seattle, U.S.A.
F*01010302 IHW01143,
IHW01152		 AY645752 Daniel E. Geraghty, Seattle, U.S.A.
F*01010303 MT14B AF523290 Daniel E. Geraghty, Seattle, U.S.A.
F*01010304 435,
1350,
1199		 AF523293,
AF523296,
AF523297		 Daniel E. Geraghty, Seattle, U.S.A.
F*0102 JHUAA0527,
JHUAA0529,
JHUAA0530		 AY645747 Daniel E. Geraghty, Seattle, U.S.A.
F*01030101 SCHU,
HOM-2,
ARBO		 AF523284,
AF523291,
AF523292		 Daniel E. Geraghty, Seattle, U.S.A.
F*01030102 JHUAA0528,
JHUAA0529,
JHUAA0530,
IHW01173,
IHW01182,
IHW01184		 AY645748,
AY645754		 Daniel E. Geraghty, Seattle, U.S.A.
F*0104 IHW01181,
IHW01182		 AY645755 Daniel E. Geraghty, Seattle, U.S.A.
G*01010102 JHUAA0394,
JHUAA0396		 AY645762 Daniel E. Geraghty, Seattle, U.S.A.
G*01010103 HAN19-02,
HAN19-04		 AY645775 Daniel E. Geraghty, Seattle, U.S.A.
G*01010104 JHUAA0393 AY645760 Daniel E. Geraghty, Seattle, U.S.A.
G*01010105 JHUAA0393,
JHUAA0396,
JHUAA0528,
JHUAA0529,
JHUAA0530		 AY645761,
AY645764,
AF523298		 Daniel E. Geraghty, Seattle, U.S.A.
G*01010202 JHUAA0528,
HAN19-01,
HAN19-04		 AY645766,
AY645776		 Daniel E. Geraghty, Seattle, U.S.A.
G*010109 JHUAA0527,
JHUAA0529,
JHUAA0530		 AY645765 Daniel E. Geraghty, Seattle, U.S.A.
G*010110 IHW01182,
IHW01184,
IHW01173		 AY645773 Daniel E. Geraghty, Seattle, U.S.A.
G*0107 JHUAA0527 AY645767 Daniel E. Geraghty, Seattle, U.S.A.
DPB1*1402 ANAN324819AN AM039828 Ann-Margaret Little, London, U.K.
DQB1*0627 05103245 AJ965439 Veronika Brixner, Frankfurt, Germany
DRB1*0454 NT00603 DQ112548 Carolyn K. Hurley, Washington, U.S.A.
DRB1*0455 NT00581 DQ112549 Carolyn K. Hurley, Washington, U.S.A.
DRB1*0456 FASO DQ130065 Lia Mele, Alessandria, Italy
DRB1*130502 NT00610 DQ135944 Carolyn K. Hurley, Washington, U.S.A.
DRB1*1369 R222 AY225520 Susana G. Rodriguez-Marino, Chicago, U.S.A.

Table 2: Confirmatory Sequences


Sequence Cell Identification Accession Number Submitting Author
A*0282N TER-313,
TER-314		 AM040196 Rainer Blasczyk, Hannover, Germany
A*03010102N 41982 AM041068 Laura Hammond, Pontyclun, U.K.
A*2420 TBC54975 AB218626 Masahiro Satake, Shibuya-ku, Tokyo, Japan
B*15010102N 29139 AM048844 Laura Hammond, Pontyclun, U.K.
B*4052 35285 AM050133 Laura Hammond, Pontyclun, U.K.
Cw*0722 NT00609 DQ135945,
DQ135946		 Carolyn K. Hurley, Washington, U.S.A.
F*01010101 WT24,
WDV		 AF523287,
AF523288		 Daniel E. Geraghty, Seattle, U.S.A.
F*01010201 JHUAA0393 AY645743 Daniel E. Geraghty, Seattle, U.S.A.
G*01010101 IHW01141,
IHW01182,
IHW01181,
IHW01175,
IHW01184,
HAN19-01,
HAN19-05		 AY645768,
AY645770,
AY645771,
AY645774		 Daniel E. Geraghty, Seattle, U.S.A.
G*01010201 IHW01141,
IHW01143,
IHW01152		 AY645769 Daniel E. Geraghty, Seattle, U.S.A.
G*010106 JHUAA0394 AY645763 Daniel E. Geraghty, Seattle, U.S.A.
G*0103 IHW01175,
IHW01181		 AY645772 Daniel E. Geraghty, Seattle, U.S.A.
G*010401 LKT3 AB088083 Hidetoshi Inoko, Isehara, Kanagawa, Japan
G*0105N LBF AF523299 Daniel E. Geraghty, Seattle, U.S.A.

 

Table 3: Recently Published Sequences


Sequence References
A*0278 (1)
A*2442 (2)
B*1586 (3)
Cw*0208 (4)
Cw*160102 (5)
DRB1*1212 (3)
DPB1*0403 (6)

References

  1. Ji Y, Sun JL, Du KM, et al.: Identification of a novel HLA-A*0278 allele in a Chinese family. Tissue Antigens 2005 65:564-6.
  2. Witter K, Sala M, Zahn R, McNicholas A, Volgger A, Albert ED: A novel A*24 allele, A*2442, was detected through routine bone marrow donor screening. Tissue Antigens 2005 65:567-70.
  3. Yan LX, Zhu FM, Lv QF, Zhang W: Identification of a new HLA-DRB1 allele, HLA-DRB1*1212, and confirmation of HLA-B*1586*. Tissue Antigens 2005 65:582-3.
  4. Canossi A, Aureli A, Piancatelli D, et al.: Characterization of a novel HLA-Cw*02 variant, Cw*0208, in a Caucasian individual. Tissue Antigens 2005 65:575-9.
  5. Nesci S, Iliescu A, Buffi O, et al.: A novel HLA-Cw*16 allele, Cw*160102, identified by cloning and sequencing. Tissue Antigens 2005 65:580-1.
  6. Weston A, Ensey JS, Frye BL: DNA-sequence determination of exon 2 of a novel HLA-DPB1 allele, DPB1*0403. DNA Sequence 2005 16:235-6