Nomenclature for Factors of the HLA System

April 2012

Compiled by Steven G. E. Marsh for the WHO Nomenclature Committee for Factors of the HLA System.

Published In:

The following sequences have been submitted to the Nomenclature Committee since the March 2012 nomenclature update and, following agreed policy, have been assigned official allele designations. Full details of all sequences will be published in a forthcoming report.

Below are listed the newly assigned sequences (Table 1) and confirmations of previously reported sequences (Table 2). The accession number of each sequence is given and these can be used to retrieve the sequence files from the EMBL, GenBank or DDBJ data libraries. Although accession numbers have been assigned by the data-libraries and most sequences are already available, there is still the possibility that an author may not yet have allowed the sequence to be released; in such a case you will have to contact the submitting author directly. Additional information pertaining to new sequences is often included in the publications describing these alleles; a listing of recent publications that describe new HLA sequences is given in Table 3.

All new and confirmatory sequences should now be submitted directly to the WHO Nomenclature Committee for Factors of the HLA System via the IMGT/HLA Database using the sequence submission tool provided (2). The IMGT/HLA Database may be accessed via the world wide web at : http://ww.ebi.ac.uk/imgt/hla/.

Table 1: New Sequences


Sequence Cell identification Accession number Submitting author
A*01:01:46HG00003532JQ007597Histogenetics, Ossining, USA
A*01:01:47HG00003535JN205170Histogenetics, Ossining, USA
A*01:110HG00003524JN786891Histogenetics, Ossining, USA
A*01:111HG00003528JN675295Histogenetics, Ossining, USA
A*01:112HG00003534JN124024Histogenetics, Ossining, USA
A*02:01:74HG00003572JQ031228Histogenetics, Ossining, USA
A*02:01:75HG00003580JN406431Histogenetics, Ossining, USA
A*02:01:76HG00003604JQ048669Histogenetics, Ossining, USA
A*02:01:77HG00003605JQ237653Histogenetics, Ossining, USA
A*02:01:78HG00003608JQ085355Histogenetics, Ossining, USA
A*02:06:12HG00003568JN124025Histogenetics, Ossining, USA
A*02:359HG00003567JN786890Histogenetics, Ossining, USA
A*02:360HG00003571JQ237650Histogenetics, Ossining, USA
A*02:361HG00003578JQ007612Histogenetics, Ossining, USA
A*02:362HG00003581JN406447Histogenetics, Ossining, USA
A*02:363HG00003582JN675298Histogenetics, Ossining, USA
A*02:364HG00003587JN124132Histogenetics, Ossining, USA
A*02:365HG00003588JN675299Histogenetics, Ossining, USA
A*02:366NHG00003602JN695240Histogenetics, Ossining, USA
A*02:367HG00003606,
HG00003607
JN242431,
JN418815
Histogenetics, Ossining, USA
A*02:368HG00003609JN675282Histogenetics, Ossining, USA
A*02:3697311122676JQ801732Yuping Su, Yueyang, China
A*02:370H12059JQ811553Lixing Yan, Hangzhou, China
A*03:05:02HG00003541JN786892Histogenetics, Ossining, USA
A*03:17:02HG00003546JN786888Histogenetics, Ossining, USA
A*03:144HG00003525JQ237616Histogenetics, Ossining, USA
A*03:145HG00003537JN124106Histogenetics, Ossining, USA
A*03:146HG00003543JN695241Histogenetics, Ossining, USA
A*03:147HG00003563JN418816Histogenetics, Ossining, USA
A*03:148HG00003564JQ007607Histogenetics, Ossining, USA
A*03:149HG00003565,
HG00003566
JN124157,
JQ031224
Histogenetics, Ossining, USA
A*03:150UA2011tp3764HE775263Mats Bengtsson, Uppsala, Sweden
A*11:01:41HG00003476JQ237618Histogenetics, Ossining, USA
A*11:123HG00003482JQ007613Histogenetics, Ossining, USA
A*23:52HG00003509JQ007624Histogenetics, Ossining, USA
A*23:53HG00003519JQ007604Histogenetics, Ossining, USA
A*24:02:57HG00003523JN124116Histogenetics, Ossining, USA
A*24:02:58HG00003570JQ031222Histogenetics, Ossining, USA
A*24:200HG00003507JQ237619Histogenetics, Ossining, USA
A*24:201HG00003508JN644961Histogenetics, Ossining, USA
A*24:202HG00003512JQ085363Histogenetics, Ossining, USA
A*24:203HG00003513JN406402Histogenetics, Ossining, USA
A*26:75HG00003484JN124159Histogenetics, Ossining, USA
A*26:76HG00003492JN675278Histogenetics, Ossining, USA
A*29:01:04HG00003462JN124172Histogenetics, Ossining, USA
A*29:36HG00003469,
HG00003470
JQ007623,
JN406386
Histogenetics, Ossining, USA
A*29:37HG00003522JQ007603Histogenetics, Ossining, USA
A*29:381185223JQ815888Eduard Palou, Barcelona, Spain
A*30:01:06HG00003503JN675279Histogenetics, Ossining, USA
A*30:02:06HG00003500JQ007628Histogenetics, Ossining, USA
A*30:02:07HG00003504JQ007629Histogenetics, Ossining, USA
A*30:64HG00003498JN124134Histogenetics, Ossining, USA
A*30:65HG00003501JN205171Histogenetics, Ossining, USA
A*31:01:14HG00003458JN124129Histogenetics, Ossining, USA
A*31:63HG00003455JQ031226Histogenetics, Ossining, USA
A*31:64HG00003459JN124020Histogenetics, Ossining, USA
A*32:42HG00003463JN786887Histogenetics, Ossining, USA
A*32:43HG00003526JQ007614Histogenetics, Ossining, USA
A*32:44HG00003560JN124001Histogenetics, Ossining, USA
A*32:45NHG00003561JN695239Histogenetics, Ossining, USA
A*33:60HG00003468JN124160Histogenetics, Ossining, USA
A*33:617311123191JQ801733Yuping Su, Yueyang, China
A*68:01:16HG00003497JN124105Histogenetics, Ossining, USA
A*68:89HG00003491JQ237620Histogenetics, Ossining, USA
A*68:90HG00003495JQ007622Histogenetics, Ossining, USA
A*68:91HG00003496JN124158Histogenetics, Ossining, USA
A*68:921144354JQ815887Eduard Palou, Barcelona, Spain
B*07:155JMDP36K0156AB703627Kenji Tadokoro, Tokyo, Japan
B*07:156212970HE801225Klaus Witter, München, Germany
B*08:89HG00003222JN124301Histogenetics, Ossining, USA
B*08:90HG00003656JN123836Histogenetics, Ossining, USA
B*08:91HG00003658JN123847Histogenetics, Ossining, USA
B*08:92HG00003662JN119416Histogenetics, Ossining, USA
B*13:02:13342193HE687288 Edward KL Yang, Hualien, Taiwan
B*13:55HG00003617JN561732Histogenetics, Ossining, USA
B*13:56NHG00003665JN119370Histogenetics, Ossining, USA
B*13:57HG00003666JQ085347Histogenetics, Ossining, USA
B*15:02:067311120111JQ801734Yuping Su, Yueyang, China
B*15:245QJMDP36K0124AB703621Kenji Tadokoro, Tokyo, Japan
B*15:246NJMDP01K0131AB704392Kenji Tadokoro, Tokyo, Japan
B*15:247PHEE B15HE797790Valerie Dubois, Lyon, France
B*18:01:17HG00003654JQ048690Histogenetics, Ossining, USA
B*18:44:02HG00003655JQ007646Histogenetics, Ossining, USA
B*18:72HG00003645JN123811Histogenetics, Ossining, USA
B*18:73HG00003646,
HG00003647
JN124210,
JN584518
Histogenetics, Ossining, USA
B*18:74NHG00003649JQ007630Histogenetics, Ossining, USA
B*18:75HG00003650,
HG00003651
JN123821,
JN123816
Histogenetics, Ossining, USA
B*18:76HG00003653JN123824Histogenetics, Ossining, USA
B*27:05:19HG00003635JN123806Histogenetics, Ossining, USA
B*27:90HG00003638JN119389Histogenetics, Ossining, USA
B*27:91HG00003642JQ007632Histogenetics, Ossining, USA
B*27:92YKKK B27HE797789Valerie Dubois, Lyon, France
B*35:201HG00003664JN695255Histogenetics, Ossining, USA
B*35:202JMDP36K0136AB703625Kenji Tadokoro, Tokyo, Japan
B*35:203BY00923JQ896291Carolyn K Hurley, Washington DC, USA
B*37:345777JQ839277Francisco de Paula Sanchez Gordo, Malaga, Spain
B*40:01:257311122931JQ801735Yuping Su, Yueyang, China
B*40:194HG00003615JQ048677Histogenetics, Ossining, USA
B*40:195HG00003616JQ007637Histogenetics, Ossining, USA
B*40:196HG00003620JN124214Histogenetics, Ossining, USA
B*40:197HG00003621JQ237623Histogenetics, Ossining, USA
B*40:198HG00003623JN675296Histogenetics, Ossining, USA
B*40:199HG00003624JN123791Histogenetics, Ossining, USA
B*40:200HG00003627JN119411Histogenetics, Ossining, USA
B*40:201HG00003628JN406416Histogenetics, Ossining, USA
B*40:202HG00003631JQ007654Histogenetics, Ossining, USA
B*40:203HG00003632JQ237634Histogenetics, Ossining, USA
B*40:204JMDP01K0111AB703622Kenji Tadokoro, Tokyo, Japan
B*40:205JMDP01K0113AB703623Kenji Tadokoro, Tokyo, Japan
B*40:206MDA0000004JQ804939Kai Cao, Houston, USA
B*40:2077311123430JQ801736Yuping Su, Yueyang, China
B*42:17HG00003643JN124334Histogenetics, Ossining, USA
B*46:317311121953JQ801730Min Dai, Yueyang, China
B*49:21HG00003618JN123803Histogenetics, Ossining, USA
B*50:17BY00926JQ896286Carolyn K Hurley, Washington DC, USA
B*51:1327311120313JQ801729Min Dai, Yueyang, China
B*51:133JMDP01K0132AB703628Kenji Tadokoro, Tokyo, Japan
B*54:01:03H12075JQ811554Lixing Yan, Hangzhou, China
B*54:27JMDP36K0144AB703626Kenji Tadokoro, Tokyo, Japan
C*01:67HG00003221JN124436Histogenetics, Ossining, USA
C*01:68HG00003225JN124477Histogenetics, Ossining, USA
C*01:69NHG00003227JN119564Histogenetics, Ossining, USA
C*02:57HG00003325JN604863Histogenetics, Ossining, USA
C*02:58MDA0000006JQ812696Kai Cao, Houston, USA
C*03:03:19HG00003351JN561739Histogenetics, Ossining, USA
C*03:04:27HG00003345JN584525Histogenetics, Ossining, USA
C*03:04:28HG00003354JN124464Histogenetics, Ossining, USA
C*03:116:02HG00003343JN406429Histogenetics, Ossining, USA
C*03:147HG00003206JN604865Histogenetics, Ossining, USA
C*03:148HG00003334JN124512Histogenetics, Ossining, USA
C*03:149HG00003335JN561750Histogenetics, Ossining, USA
C*03:150HG00003339JN124497Histogenetics, Ossining, USA
C*03:151HG00003340JN406474Histogenetics, Ossining, USA
C*03:152HG00003342JN124493Histogenetics, Ossining, USA
C*03:153HG00003344JN119430Histogenetics, Ossining, USA
C*03:154HG00003349JN124487Histogenetics, Ossining, USA
C*03:155HG00003352,
HG00003353
JN406426,
JN406476
Histogenetics, Ossining, USA
C*03:156HG00003355JN124514Histogenetics, Ossining, USA
C*04:01:38HG00003213JN124376Histogenetics, Ossining, USA
C*04:01:39HG00003220JN242442Histogenetics, Ossining, USA
C*04:113HG00003215JN124451Histogenetics, Ossining, USA
C*04:114HG00003217,
HG00003218
JN604864,
JN584523
Histogenetics, Ossining, USA
C*04:115NHG00003219JN119559Histogenetics, Ossining, USA
C*04:116HG00003363JN242450Histogenetics, Ossining, USA
C*04:117HG00003368JN124551Histogenetics, Ossining, USA
C*04:118Q-693398HE799692Rainer Blasczyk, Hannover, Germany
C*05:01:19HG00003287JN124527Histogenetics, Ossining, USA
C*05:01:20HG00003293,
HG00003294
JN205228,
JN418835
Histogenetics, Ossining, USA
C*05:75HG00003289JN584521Histogenetics, Ossining, USA
C*05:76HG00003292JN604878Histogenetics, Ossining, USA
C*05:77HG00003297JN418832Histogenetics, Ossining, USA
C*05:78HG00003361JN124473Histogenetics, Ossining, USA
C*06:02:20HG00003247JN124552Histogenetics, Ossining, USA
C*06:77HG00003228JN124516Histogenetics, Ossining, USA
C*06:78HG00003233JN124520Histogenetics, Ossining, USA
C*06:79NHG00003239JN119565Histogenetics, Ossining, USA
C*06:80HG00003242JN124515Histogenetics, Ossining, USA
C*06:81HG00003248,
HG00003249
JN124489,
JN124491
Histogenetics, Ossining, USA
C*06:82HG00003250JN644977Histogenetics, Ossining, USA
C*07:01:01:02H581HE793165Carlos Vilches, Madrid, Spain
C*07:01:25HG00003278JN124536Histogenetics, Ossining, USA
C*07:01:26HG00003281JN629062Histogenetics, Ossining, USA
C*07:02:31HG00003235JN561749Histogenetics, Ossining, USA
C*07:02:32HG00003270,
HG00003271
JN182993,
JN629064
Histogenetics, Ossining, USA
C*07:02:33HG00003277JN124513Histogenetics, Ossining, USA
C*07:141:02HG00003254JN561740Histogenetics, Ossining, USA
C*07:141:02BY00921JQ896290Carolyn K Hurley, Washington DC, USA
C*07:236HG00003237JN124566Histogenetics, Ossining, USA
C*07:237HG00003256JN124475Histogenetics, Ossining, USA
C*07:238HG00003262,
HG00003263,
HG00003264
JN124518,
JN124519,
JN124503
Histogenetics, Ossining, USA
C*07:239HG00003266JN604870Histogenetics, Ossining, USA
C*07:240HG00003267JN242454Histogenetics, Ossining, USA
C*07:241HG00003268JN205221Histogenetics, Ossining, USA
C*07:242HG00003272JN124486Histogenetics, Ossining, USA
C*07:243HG00003273,
HG00003274
JN124494,
JN124495
Histogenetics, Ossining, USA
C*07:244HWS111201JQ824202Oh-Joong Kwon, Seoul, South Korea
C*08:61HG00003296JN124523Histogenetics, Ossining, USA
C*08:62PM54HE793166Carlos Vilches, Madrid, Spain
C*12:03:21HG00003312JN644975Histogenetics, Ossining, USA
C*12:03:22HG00003315,
HG00003316
JN205225,
JN182988
Histogenetics, Ossining, USA
C*12:77HG00003309JN406467Histogenetics, Ossining, USA
C*12:78HG00003314JN242446Histogenetics, Ossining, USA
C*12:79HG00003319JN584529Histogenetics, Ossining, USA
C*14:02:11HG00003359JN119427Histogenetics, Ossining, USA
C*14:24:02HG00003356,
HG00003357
JN124547,
JN124548
Histogenetics, Ossining, USA
C*14:38HG00003208JN124405Histogenetics, Ossining, USA
C*14:39HG00003209JN124372Histogenetics, Ossining, USA
C*14:40HG00003360JN604879Histogenetics, Ossining, USA
C*14:41HG00003374JN629063Histogenetics, Ossining, USA
C*16:46HG00003298JN119428Histogenetics, Ossining, USA
C*16:47HG00003299JN124471Histogenetics, Ossining, USA
C*16:48HG00003300JN124492Histogenetics, Ossining, USA
C*16:49HG00003304,
HG00003305
JN604871,
JN604869
Histogenetics, Ossining, USA
C*17:12HG00003320JN124553Histogenetics, Ossining, USA
DRB1*01:01:22HG00003445JN406380Histogenetics, Ossining, USA
DRB1*01:46HG00003443JN584530Histogenetics, Ossining, USA
DRB1*01:47HG00003444JN242458Histogenetics, Ossining, USA
DRB1*01:48HG00003447JN119486Histogenetics, Ossining, USA
DRB1*01:49HG00003451JN561760Histogenetics, Ossining, USA
DRB1*03:01:20HG00003404JN205239Histogenetics, Ossining, USA
DRB1*03:82HG00003407JN119519Histogenetics, Ossining, USA
DRB1*03:83HG00003409JN119533Histogenetics, Ossining, USA
DRB1*04:105:02HG00003397,
HG00003398
JN182995,
JN406491
Histogenetics, Ossining, USA
DRB1*04:109HG00003391JN119553Histogenetics, Ossining, USA
DRB1*04:110HG00003392JN119556Histogenetics, Ossining, USA
DRB1*04:111HG00003402JN561767Histogenetics, Ossining, USA
DRB1*04:112DKMS-LSL-DRB1-5AB602493DKMS Life Science Lab, Dresden, Germany
DRB1*04:113DKMS-LSL-DRB1-6AB602494DKMS Life Science Lab, Dresden, Germany
DRB1*09:187311120273JQ801737Yuping Su, Yueyang, China
DRB1*11:04:09HG00003437JN119517Histogenetics, Ossining, USA
DRB1*11:04:10HG00003441JN242459Histogenetics, Ossining, USA
DRB1*11:06:03HG00003405JN119515Histogenetics, Ossining, USA
DRB1*11:127HG00003426JN119546Histogenetics, Ossining, USA
DRB1*11:128HG00003436JN584531Histogenetics, Ossining, USA
DRB1*13:01:12HG00003414JN119544Histogenetics, Ossining, USA
DRB1*13:01:137311121436JQ801731Min Dai, Yueyang, China
DRB1*13:02:06HG00003416JN119532Histogenetics, Ossining, USA
DRB1*13:02:07HG00003442JN604882Histogenetics, Ossining, USA
DRB1*13:97:02HG00003413JN418845Histogenetics, Ossining, USA
DRB1*13:140HG00003415JN119514Histogenetics, Ossining, USA
DRB1*13:141HG00003417,
HG00003418
JN406487,
JN119516
Histogenetics, Ossining, USA
DRB1*13:142NHG00003420JN561759Histogenetics, Ossining, USA
DRB1*15:01:19HG00003376JN561762Histogenetics, Ossining, USA
DRB1*15:06:02HG00003379JN119505Histogenetics, Ossining, USA
DRB1*15:72HG00003377JN119511Histogenetics, Ossining, USA
DRB1*15:73HG00003380JN119500Histogenetics, Ossining, USA
DRB1*15:74 HG00003384,
HG00003385
JN561761,
JN406382
Histogenetics, Ossining, USA
DRB1*15:75HG00003390JN418844Histogenetics, Ossining, USA
DQB1*05:15H12038JQ828988Lixing Yan, Hangzhou, China
DQB1*06:50MDA0000005JQ804940Kai Cao, Houston, USA
DQB1*06:51SH003AB710180Hiroshi Furukawa, Sagamihara, Japan

Table 2: Confirmatory Sequences


Sequence Cell identification Accession number Submitting author
A*23:01:091141448JQ815889Eduard Palou, Barcelona, Spain
A*24:11NArtbroleHE648923Paul Dunn, Auckland, New Zealand
B*15:70JMDP01K0106AB704094Kenji Tadokoro, Tokyo, Japan
B*35:124JMDP36K113AB704093Kenji Tadokoro, Tokyo, Japan
B*35:191BY00927JQ896285Carolyn K Hurley, Washington DC, USA
B*35:19396006470JQ844125Daniel Fuerst, Ulm, Germany
B*39:12JMDP36K0142AB704097Kenji Tadokoro, Tokyo, Japan
B*39:12MDA0000007JQ823182Kai Cao, Houston, USA
B*46:30JMDP01K0110AB704095Kenji Tadokoro, Tokyo, Japan
B*51:37JMDP36K0143AB704098Kenji Tadokoro, Tokyo, Japan
B*52:02JMDP01K0112AB704096Kenji Tadokoro, Tokyo, Japan
C*02:14BY00924JQ896288Carolyn K Hurley, Washington DC, USA
C*07:186BY00922JQ896289Carolyn K Hurley, Washington DC, USA
C*16:35BY00920JQ896292Carolyn K Hurley, Washington DC, USA
DRB1*03:71MDA0000003JQ804938Kai Cao, Houston, USA
DRB1*11:84:02HG00003430JN242460Histogenetics, Ossining, USA

Table 3: Recently Published Sequences


Sequence References
A*02:01:64(3)
A*02:319(3)
A*02:330(4)
A*11:108(4)
A*31:53(5)
A*32:22(6)
A*66:14(7)
B*08:01:08(8)
B*15:01:18(9)
B*27:25(10)
B*27:86(10)
B*35:87(11)
B*40:175(4)
B*40:176(4)
B*44:110(9)
B*51:63(12)
C*04:01:22(9)
MICA*010:02(13)
DQB1*03:03:04(14)
DQB1*05:14(9)
DPB1*06:01(15)
DPB1*10:01(15)
DPB1*11:01:01(15)
DPB1*16:01(15)
DPB1*17:01(15)
DPB1*18:01(15)
DPB1*21:01(15)
DPB1*26:01:02(15)
DPB1*27:01(15)
DPB1*39:01(15)
DPB1*131:01(15)
DPB1*135:01(15)

References:

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