Nomenclature for Factors of the HLA System

July 2011

Compiled by Steven G. E. Marsh for the WHO Nomenclature Committee for Factors of the HLA System.

Published In:

The following sequences have been submitted to the Nomenclature Committee since the June 2011 nomenclature update and, following agreed policy, have been assigned official allele designations. Full details of all sequences will be published in a forthcoming report.

Below are listed the newly assigned sequences (Table 1) and confirmations of previously reported sequences (Table 2). The accession number of each sequence is given and these can be used to retrieve the sequence files from the EMBL, GenBank or DDBJ data libraries. Although accession numbers have been assigned by the data-libraries and most sequences are already available, there is still the possibility that an author may not yet have allowed the sequence to be released; in such a case you will have to contact the submitting author directly. Additional information pertaining to new sequences is often included in the publications describing these alleles; a listing of recent publications that describe new HLA sequences is given in Table 3.

All new and confirmatory sequences should now be submitted directly to the WHO Nomenclature Committee for Factors of the HLA System via the IMGT/HLA Database using the sequence submission tool provided (2). The IMGT/HLA Database may be accessed via the world wide web at : http://ww.ebi.ac.uk/imgt/hla/.

Table 1: New Sequences


Sequence Cell identification Accession number Submitting author
A*02:3272801053383FR875093Jue Wang, Chengdu, China
A*11:01:33281152619FR873838Jue Wang, Chengdu, China
A*11:01:342801052777FR874112Jue Wang, Chengdu, China
A*11:1072801053020FR875092Jue Wang, Chengdu, China
A*24:183NJRC-D01-041AB645763Kenji Tadokoro, Tokyo, Japan
A*31:55281052707FR874111Jue Wang, Chengdu, China
B*13:51BY00840JN132205Carolyn K Hurley, Washington DC, USA
B*13:522801052819FR875091Jue Wang, Chengdu, China
B*15:235BY00842JN132206Carolyn K Hurley, Washington DC, USA
B*40:174Shanxi011JN133620Demei Zhang, Taiyuan, China
B*44:135BY00841JN132213Carolyn K Hurley, Washington DC, USA
B*51:01:2911-989JN001934Michele Curcio, Pisa, Italy
B*52:01:10JRC-D01-061AB645765Kenji Tadokoro, Tokyo, Japan
C*07:208H11192JN256033Lixing Yan, Hangzhou, China
DRB1*04:103BY00843JN132207Carolyn K Hurley, Washington DC, USA
DRB1*10:04344030FR874045Edward KL Yang, Hualien, Taiwan
DRB1*13:120Oct-52HQ701725Michele Curcio, Pisa, Italy
DQB1*05:13NT01206JN132212Carolyn K Hurley, Washington DC, USA
DPA1*02:02:04p87014FJF923466Marie Lin, Taipei, Taiwan
MICA*007:04236JN200813Daniel Fuerst, Ulm, Germany
MICA*066GSQSZ-11JN381038Su-Qing Gao, Shenzhen, China

Table 2: Confirmatory Sequences


Sequence Cell identification Accession number Submitting author
A*01:01:17HG00001935GU551789Histogenetics, Ossining, USA
A*01:40HG00001964HQ154161Histogenetics, Ossining, USA
A*02:01:26HG00001937GU590942Histogenetics, Ossining, USA
A*02:01:26HG00001936HQ154150Histogenetics, Ossining, USA
A*02:01:37HG00001928GU551777Histogenetics, Ossining, USA
A*02:01:42HG00001927GU551772Histogenetics, Ossining, USA
A*02:01:43HG00002245HM594757Histogenetics, Ossining, USA
A*02:01:52HG00001938GU551785Histogenetics, Ossining, USA
A*02:163HG00001939GU590946Histogenetics, Ossining, USA
A*02:227NHG00001979HM467587Histogenetics, Ossining, USA
A*03:49HG00001977GU551776Histogenetics, Ossining, USA
A*03:50HG00001965HM594758Histogenetics, Ossining, USA
A*03:74HG00001976GU551793Histogenetics, Ossining, USA
A*03:79HG00001978GU551797Histogenetics, Ossining, USA
A*03:102HG00001929GU551781Histogenetics, Ossining, USA
A*11:01:15 HG00001971,
HG00001972		 GU551791,
GU551765		Histogenetics, Ossining, USA
A*11:29HG00001970GQ180312Histogenetics, Ossining, USA
A*11:47HG00001955GU811762Histogenetics, Ossining, USA
A*11:90104247PFR873837Edward KL Yang, Hualien, Taiwan
A*24:02:22HG00001924GU551773Histogenetics, Ossining, USA
A*24:02:26HG00001923GU551774Histogenetics, Ossining, USA
A*24:02:37HG00001922GU551726Histogenetics, Ossining, USA
A*24:121HG00001934,
HG00001975		GU551787,
GU551729		Histogenetics, Ossining, USA
A*25:11HG00001959HQ154175Histogenetics, Ossining, USA
A*26:01:04NT01203JN132209Carolyn K Hurley, Washington DC, USA
A*26:58CHA06-660JN252728Ji Young Huh, Sungnam-si, Korea
A*29:20BY00837JN132202Carolyn K Hurley, Washington DC, USA
A*29:21HG00001969GU551780Histogenetics, Ossining, USA
A*30:29HG00001973,
HG00001921		GU551771,
GU551730		Histogenetics, Ossining, USA
A*30:36HG00002064GU551727Histogenetics, Ossining, USA
A*30:51HG00001974HM362810Histogenetics, Ossining, USA
A*31:01:04HG00001968HM004297Histogenetics, Ossining, USA
A*32:24HG00001926GU551754Histogenetics, Ossining, USA
A*33:27HG00001967GU551794Histogenetics, Ossining, USA
A*33:27HG00002244GU551753Histogenetics, Ossining, USA
B*07:02:08HG00002052GQ401189Histogenetics, Ossining, USA
B*07:02:10HG00001961,
HG00001962		GU551841,
HQ154194		Histogenetics, Ossining, USA
B*07:02:15HG00002249GU354106Histogenetics, Ossining, USA
B*07:73HG00002062GU228815Histogenetics, Ossining, USA
B*07:77HG00002056GQ279268Histogenetics, Ossining, USA
B*07:94HG00002060GU590970Histogenetics, Ossining, USA
B*07:98HG00001960HM467512Histogenetics, Ossining, USA
B*07:109HG00002063GU187924Histogenetics, Ossining, USA
B*08:01:08HG00002000,
HG00002001		GQ245751,
GQ900545		Histogenetics, Ossining, USA
B*08:01:15HG00002004GU354101Histogenetics, Ossining, USA
B*08:63HG00002003GU354114Histogenetics, Ossining, USA
B*15:03:03HG00002042GU551820Histogenetics, Ossining, USA
B*15:170HG00002014,
HG00002015,
HG00002016		GQ245717,
GQ279262,
GQ245718		Histogenetics, Ossining, USA
B*15:171HG00002006HM594778Histogenetics, Ossining, USA
B*15:181NHG00002030HQ226118Histogenetics, Ossining, USA
B*15:183HG00002248GU187926Histogenetics, Ossining, USA
B*15:211HG00002031GQ245726Histogenetics, Ossining, USA
B*18:01:05HG00002250HM187698Histogenetics, Ossining, USA
B*18:40HG00001998GQ491083Histogenetics, Ossining, USA
B*18:49HG00002246GU551810Histogenetics, Ossining, USA
B*27:05:15HG00001994GU354105Histogenetics, Ossining, USA
B*27:61HG00001953HM467515Histogenetics, Ossining, USA
B*35:01:19HG00001957GU551814Histogenetics, Ossining, USA
B*35:05:02HG00002017GU187923Histogenetics, Ossining, USA
B*35:14:01CS00098JN184624Kai Cao, Los Angeles, USA
B*35:43:01CS00103JN223013Kai Cao, Los Angeles, USA
B*35:104HG00002024GU187929Histogenetics, Ossining, USA
B*35:106HG00001956GU551813Histogenetics, Ossining, USA
B*35:116HG00002021,
HG00002022		GU354103,
GU228810		Histogenetics, Ossining, USA
B*35:121HG00002020GQ279267Histogenetics, Ossining, USA
B*35:144HG00002023GU127994Histogenetics, Ossining, USA
B*37:01:07HG00001995GU228819Histogenetics, Ossining, USA
B*37:04:02HG00001997GU128008Histogenetics, Ossining, USA
B*37:17HG00001996GU551846Histogenetics, Ossining, USA
B*38:01:04HG00001980GU289890Histogenetics, Ossining, USA
B*38:24HG00002061GQ132051Histogenetics, Ossining, USA
B*39:02:02CS00099JN184625Kai Cao, Los Angeles, USA
B*39:24:01CS00100JN190432Kai Cao, Los Angeles, USA
B*40:01:07HG00001985GU228809Histogenetics, Ossining, USA
B*40:02:06HG00001991GU187927Histogenetics, Ossining, USA
B*40:27:01CS00076, CS00105JN090126Kai Cao, Los Angeles, USA
B*40:107HG00001990GU128007Histogenetics, Ossining, USA
B*40:111HG00001992GQ401186Histogenetics, Ossining, USA
B*40:157HG00001989GU354117Histogenetics, Ossining, USA
B*40:168HG00001952GU551840Histogenetics, Ossining, USA
B*44:77HG00002009GQ279274Histogenetics, Ossining, USA
B*44:86HG00002247GU551809Histogenetics, Ossining, USA
B*44:120HG00002010,
HG00002011		GU228821,
GU228818		Histogenetics, Ossining, USA
B*44:122HG00002008GU354104Histogenetics, Ossining, USA
B*49:09HG00001983GQ279271Histogenetics, Ossining, USA
B*49:11HG00001984GQ279270Histogenetics, Ossining, USA
B*49:15HG00001981GQ254329Histogenetics, Ossining, USA
B*50:11HG00001986GU187928Histogenetics, Ossining, USA
B*50:12HG00001950,
HG00001951		GU590963,
GQ345059		Histogenetics, Ossining, USA
B*51:01:20HG00002048GQ279276Histogenetics, Ossining, USA
B*51:65HG00002044,
HG00002045		GQ245724,
GU551833		Histogenetics, Ossining, USA
B*51:69HG00002046,
HG00002047		GU551824,
GQ279269		Histogenetics, Ossining, USA
B*51:73HG00002043GU551817Histogenetics, Ossining, USA
B*51:83HG00002050GU354113Histogenetics, Ossining, USA
B*51:100HG00001958HM467514Histogenetics, Ossining, USA
B*51:122HG00002049GU228813Histogenetics, Ossining, USA
B*56:01:04HG00002039GU354098Histogenetics, Ossining, USA
B*56:27HG00002040GU354115Histogenetics, Ossining, USA
B*57:01:10HG00002032GU354119Histogenetics, Ossining, USA
B*57:21HG00002037GU551823Histogenetics, Ossining, USA
B*57:24HG00002035GQ859529Histogenetics, Ossining, USA
B*57:35HG00002029GU551836Histogenetics, Ossining, USA
B*57:39HG00001987,
HG00001988		GU128014,
GU128015		Histogenetics, Ossining, USA
B*57:43HG00002033,
HG00002034		GU128001,
GU127993		Histogenetics, Ossining, USA
B*58:07NT01204JN132210
B*58:23HG00002028GQ279279Histogenetics, Ossining, USA
C*02:02:16HG00002141,
HG00002142,
HG00002143,
HG00002144		GU551890,
GU551892,
GU551893,
GU551894		Histogenetics, Ossining, USA
C*02:16:02HG00002254GU128021Histogenetics, Ossining, USA
C*02:31HG00002140GU228837Histogenetics, Ossining, USA
C*02:34HG00002136GU551901Histogenetics, Ossining, USA
C*02:38NHG00002138,
HG00002139		GU354121,
GU354122		Histogenetics, Ossining, USA
C*03:04:11HG00002151GU551863Histogenetics, Ossining, USA
C*03:04:13HG00002148GU228839Histogenetics, Ossining, USA
C*03:51HG00002256GU228838Histogenetics, Ossining, USA
C*03:53HG00002152GU551851Histogenetics, Ossining, USA
C*03:69HG00002154GU551889Histogenetics, Ossining, USA
C*04:01:08HG00002163,
HG00002164		GU551873,
GU289896		Histogenetics, Ossining, USA
C*04:01:09HG00002161GU136158Histogenetics, Ossining, USA
C*04:01:13HG00002169GU354127Histogenetics, Ossining, USA
C*04:29CS00107JN252967Kai Cao, Los Angeles, USA
C*04:37HG00002167HM562340Histogenetics, Ossining, USA
C*04:47HG00002159GU136161Histogenetics, Ossining, USA
C*04:56HG00002258GU551869Histogenetics, Ossining, USA
C*04:63HG00002160GU354125Histogenetics, Ossining, USA
C*04:65HG00002165GU551868Histogenetics, Ossining, USA
C*04:69HG00002168GU354131Histogenetics, Ossining, USA
C*05:01:11HG00002108,
HG00002109		GU551875,
GU289900		Histogenetics, Ossining, USA
C*05:01:17HG00002114GU354128Histogenetics, Ossining, USA
C*05:19HG00002112GQ240433Histogenetics, Ossining, USA
C*05:28HG00002133GU289895Histogenetics, Ossining, USA
C*06:02:07HG00002074,
HG00002075		GU551888,
GU551883		Histogenetics, Ossining, USA
C*06:30HG00002263GU551854Histogenetics, Ossining, USA
C*06:43HG00002072GU590979Histogenetics, Ossining, USA
C*06:59HG00002073GU289899Histogenetics, Ossining, USA
C*07:01:15HG00002079GU228824Histogenetics, Ossining, USA
C*07:02:11HG00002105GU551860Histogenetics, Ossining, USA
C*07:60HG00002091GQ180395Histogenetics, Ossining, USA
C*07:85HG00002092GU228831Histogenetics, Ossining, USA
C*07:93HG00002080GU354135Histogenetics, Ossining, USA
C*07:97HG00002093GU017954Histogenetics, Ossining, USA
C*07:101HG00002070GU590974Histogenetics, Ossining, USA
C*07:104NHG00002088,
HG00002089,
HG00002090		HM768867,
HQ590539,
HQ011370		Histogenetics, Ossining, USA
C*07:106HG00002087GU551878Histogenetics, Ossining, USA
C*07:119HG00002086GU551850Histogenetics, Ossining, USA
C*07:120HG00002082,
HG00002083,
HG00002084		GU228843,
GU354132,
GU551898		Histogenetics, Ossining, USA
C*07:121QHG00002100HM159326Histogenetics, Ossining, USA
C*07:123HG00002094,
HG00002095		GU017946,
GU551866		Histogenetics, Ossining, USA
C*07:124HG00002078GU551876Histogenetics, Ossining, USA
C*07:137:02HG00002098GU551856Histogenetics, Ossining, USA
C*07:145HG00002096GU289898Histogenetics, Ossining, USA
C*07:151HG00002085GU551849Histogenetics, Ossining, USA
C*07:180HG00002104GU551859Histogenetics, Ossining, USA
C*07:192HG00002099HM044959Histogenetics, Ossining, USA
C*07:20511733049FR874006Christian Seidl, Frankfurt am Main, Germany
C*12:03:08HG00002123,
HG00002124		GU551882,
GQ994076		Histogenetics, Ossining, USA
C*12:03:10HG00002127GU551880Histogenetics, Ossining, USA
C*12:27HG00002122GU354133Histogenetics, Ossining, USA
C*12:35HG00002129GU187937Histogenetics, Ossining, USA
C*12:43HG00002117GU289902Histogenetics, Ossining, USA
C*12:63HG00002120GU551895Histogenetics, Ossining, USA
C*14:11HG00002156GQ180403Histogenetics, Ossining, USA
C*15:04CS00101JN190433Kai Cao, Los Angeles, USA
C*15:09CS00106JN251805Kai Cao, Los Angeles, USA
C*15:24HG00002146,
HG00002255		GU811798Histogenetics, Ossining, USA
C*15:28HG00002147GU551857Histogenetics, Ossining, USA
C*15:52UTZ AdeHE573590Sylvie Tourne, Strasbourg, France
C*16:15:01HG00002125GU551900Histogenetics, Ossining, USA
C*18:04HG00002069GU551862Histogenetics, Ossining, USA
DRB1*01:01:07HG00002234,
HG00002235		HM594813,
HM594812		Histogenetics, Ossining, USA
DRB1*01:01:12HG00002236GU551923Histogenetics, Ossining, USA
DRB1*01:27HG00002243GU551916Histogenetics, Ossining, USA
DRB1*03:01:12HG00002191HM594833Histogenetics, Ossining, USA
DRB1*03:05:03HG00002194GU187932Histogenetics, Ossining, USA
DRB1*03:44HG00002199,
HG00002200		HM594845,
HM594846		Histogenetics, Ossining, USA
DRB1*03:47HG00002197GQ449667Histogenetics, Ossining, USA
DRB1*04:10:01CS00104JN228360Kai Cao, Los Angeles, USA
DRB1*08:45HG00002186HM594830Histogenetics, Ossining, USA
DRB1*11:01:10HG00002223HQ230555Histogenetics, Ossining, USA
DRB1*11:01:11HG00002222HM594856Histogenetics, Ossining, USA
DRB1*11:01:13HG00002225,
HG00002226		GQ345102,
GQ345103		Histogenetics, Ossining, USA
DRB1*11:78HG00002227,
HG00002228,
HG00002229		GU128071,
GU128077,
GU128074		Histogenetics, Ossining, USA
DRB1*11:108HG00002224GU590985Histogenetics, Ossining, USA
DRB1*13:21:02HG00002215,
HG00001947,
HG00001946,
HG00001944,
HG00001945,
HG00002216,
HG00002217,
HG00002218,
HG00001943,
HG00002219,
HG00002220,
HG00002221		HM594850,
HM594851,
HM594849		Histogenetics, Ossining, USA
DRB1*13:33:03HG00002211,
HG00002212		GU228844,
HM594847		Histogenetics, Ossining, USA
DRB1*13:38HG00002213,
HG00001942		GU590989,
GQ180275		Histogenetics, Ossining, USA
DRB1*13:106HG00002205GQ345104Histogenetics, Ossining, USA
DRB1*13:111HG00002202,
HG00002260		GU551924Histogenetics, Ossining, USA
DRB1*13:112HG00001949GQ240517Histogenetics, Ossining, USA
DRB1*14:87HG00001941GU811817Histogenetics, Ossining, USA
DRB1*14:95HG00002195HM594853Histogenetics, Ossining, USA
DRB1*14:101HG00002208GU590992Histogenetics, Ossining, USA
DRB1*14:106HG00001948GQ245755Histogenetics, Ossining, USA
DRB1*15:01:11HG00001910,
HG00001909,
HG00001911,
HG00001912		HM187718,
HM187721,
HM187720,
HM187719		Histogenetics, Ossining, USA
DRB1*15:14CaturodFR874838Paul Dunn, Auckland, New Zealand
DRB1*15:55HG00002173GU128063Histogenetics, Ossining, USA
DQB1*03:16NT01152JN132208Carolyn K Hurley, Washington DC, USA
DQB1*06:08:01CS00102JN190434Kai Cao, Los Angeles, USA

Table 3: Recently Published Sequences


Sequence References Sequence References Sequence References
A*01:43(3) B*37:26 (4) DRB1*01:23 (3)
A*02:01:43(3) B*39:54 (3) DRB1*03:01:09 (3)
A*02:171:02(3) B*40:99 (3) DRB1*03:11:02 (3)
A*02:193(3) B*44:02:13 (3) DRB1*03:51 (3)
A*03:70(3) B*44:76 (3) DRB1*04:04:02 (3)
A*03:73(3) B*44:82 (3) DRB1*04:05:08 (3)
A*03:74(3) B*46:22 (3) DRB1*04:06:03 (3)
A*11:44(3) B*47:06 (3) DRB1*04:17:02 (3)
A*11:52Q(3) B*49:10 (3) DRB1*04:72:02 (3)
A*23:33(4) B*51:01:17 (3) DRB1*04:83 (3)
A*25:11(3) B*51:90 (3) DRB1*04:84 (3)
A*30:02:05(3) B*51:91 (3) DRB1*04:94N (5)
A*30:30(3) B*51:92 (3) DRB1*08:04:05 (3)
A*30:34(3) B*51:93 (3) DRB1*09:09 (3)
A*31:01:09(6) B*52:01:05 (3) DRB1*11:01:11 (3)
A*32:21(3) B*52:16 (3) DRB1*11:83 (3)
A*33:28(3) B*53:21 (3) DRB1*11:84 (3)
A*33:30(6) B*53:22 (3) DRB1*11:85 (3)
A*33:41(4) B*54:20 (3) DRB1*11:86 (3)
B*07:121(4) B*55:01:07 (4) DRB1*11:87 (3)
B*08:55(3) B*56:26 (3) DRB1*11:91 (3)
B*08:56(3) B*57:29 (7) DRB1*11:92 (3)
B*08:61(3) B*57:30 (3) DRB1*11:93 (3)
B*13:32(3) B*58:24 (3) DRB1*13:01:06 (3)
B*14:02:05(3) B*78:07 (3) DRB1*13:03:03 (3)
B*14:12(3) C*02:26:02 (3) DRB1*13:66:02 (3)
B*15:18:03(3) C*03:80 (3) DRB1*13:93 (3)
B*15:25:03(4) C*04:54 (3) DRB1*13:94 (3)
B*15:170(3) C*04:55 (3) DRB1*13:98 (3)
B*15:185(3) C*05:35 (3) DRB1*14:93 (3)
B*15:216(4) C*05:36 (3) DRB1*14:94 (3)
B*18:55(4) C*06:30 (3) DRB1*14:97 (3)
B*27:59N(3) C*06:31 (3) DRB1*15:01:07 (3)
B*27:63(3) C*14:16 (3) DQB1*06:41 (8)
B*27:74(4) C*15:27 (3) DPB1*131:01 (9)
B*35:01:10(3) C*16:20 (3)    
B*37:19(3) DRB1*01:01:16 (3)    
B*37:22(3) DRB1*01:01:18 (3)    

References:

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