Nomenclature for Factors of the HLA System

November 2008

Compiled by Steven G. E. Marsh for the WHO Nomenclature Committee for Factors of the HLA System.

Published In:

The following sequences have been submitted to the Nomenclature Committee since the October 2008 nomenclature update and, following agreed policy, have been assigned official allele designations. Full details of all sequences will be published in a forthcoming report.

Below are listed the newly assigned sequences (Table 1) and confirmations of previously reported sequences (Table 2). The accession number of each sequence is given and these can be used to retrieve the sequence files from either the EMBL, GenBank or DDBJ data libraries. Although accession numbers have been assigned by the data libraries and most sequences are already available, there is still the possibility that an author may not yet have allowed the sequence to be released, in such a case you will have to contact the submitting author directly. Additional information pertaining to new sequences is often included in the publications describing these alleles, a listing of recent publications which describe new HLA sequences is given in Table 3.

All new and confirmatory sequences should now be submitted directly to the WHO Nomenclature Committee for Factors of the HLA System via the IMGT/HLA Database using the sequence submission tool provided. The IMGT/HLA Database may be accessed via the world wide web at : http://ww.ebi.ac.uk/imgt/hla/.

Table 1: New Sequences


Sequence Cell identification Accession number Submitting author
A*030109 BJ59 FJ428217 Zhixin Zhang, Beijing, China
A*0345 175582 FM253686 Francesca Poli, Milano, Italy
A*240217 BJ58 FJ428239 Na Liu, Beijing, China
A*2496 BJ243 FJ428230 Xiaoyan Shan, Beijing, China
A*3027N CHO2008-H1 FJ185174 Elizabeth Trachtenberg, Oakland,, USA
B*2744 BJ60 FJ463035 Wei Li, Beijing, China
B*3946 BJ57 FJ358707 Zhixin Zhang, Beijing, China
B*4465 103013 FJ231109 Mary Sue Leffell, Baltimore, USA
B*5904 KPUM88 AB467317 Masaki Matsushita, Hiroshima, Japan
Cw*0223 CTM-2001095 FJ415311 Antonio Balas, Madrid, Spain
Cw*034302 APTGar FM865853 Anne Dormoy, Strasbourg, France
Cw*070403 CTM-0001222 FJ264200 Antonio Balas, Madrid, Spain
Cw*0765 MSA2,
MSD1 		FM865869 Marlis Schroeder, Winnipeg, Canada
Cw*1705 CTM-0890009 FJ434674 Antonio Balas, Madrid, Spain
G*010115 BCCR-565,
BCCR-1020,
7a031,
7b061 		FJ460463 Michel Roger, Montreal, Canada
G*010116 BCCR-1753 FJ464334 Michel Roger, Montreal, Canada
DRB1*0716 NT01011 FJ407051 Carolyn K Hurley, Washington DC, USA
DRB1*090202 2200308921182 FJ442950 Marie Lin, Taipei, Taiwan

Table 2: Confirmatory Sequences


Sequence Cell identification Accession number Submitting author
A*1110 BY00366 FJ427298 Carolyn K Hurley, Washington DC, USA
A*290201 MANN CR382333 Stephan Beck, London, United Kingdom
A*320101 SSTO BX005091 Stephan Beck, London, United Kingdom
Cw*06020101/td> DBB CR388229 Stephan Beck, London, United Kingdom
E*01010101 DBB CR762481 Stephan Beck, London, United Kingdom
E*01010101 SSTO BX936369 Stephan Beck, London, United Kingdom
F*01010108 DBB CR753818 Stephan Beck, London, United Kingdom
F*01010108 MANN BX927250 Stephan Beck, London, United Kingdom
G*01010101 DBB CR759769 Stephan Beck, London, United Kingdom
G*01010101 MCF CR788234,
CT009517		 Stephan Beck, London, United Kingdom

Table 3: Recently Published Sequences


Sequence References
A*0128 (1)
A*3318 (2)
B*5530 (3)
DRB1*1461 (4)

References

  1. Shuang C, Shan X, Zhang Z. A novel allele, HLA-A*0128, identified by sequence-based typing in a Chinese individual. Tissue Antigens. 2008 72:599-600.
  2. Li Z, Zhang LH, Zou HY, et al. HLA-A*3318, a novel allele, identified by sequence-based typing in a Chinese individual. Tissue Antigens. 2008 72:600-2.
  3. Yan LX, Zhu FM, Zhang W, He J. HLA-B*5530, a new allele was identified by sequence-based typing in a Chinese individual. Tissue Antigens. 2008 72:602-3.
  4. Wang Z, Shan X, Zhang Z. Identification of a novel HLA-DRB allele, HLA-DRB1*1461. Tissue Antigens. 2008 72:603-4.