HLADB-2.28.0-January 2010 HLA-L Nucleotide Sequence Alignments Sequences Aligned: 15 January 2010 Steven G. E. Marsh, Anthony Nolan Research Institute. Nuc. Pos. 30 60 Prot. Pos. -20 -10 -1 1 L*01010101 ATG GGG GTC ATG GCT CCC CGA ACC CTC CTC CTG CTG CTC TTG GGG GCC CTG GCC CTG ACC GAG ACC TGG GCC G | GC L*01010102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- - | -- L*01010103 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- - | -- L*010102 --- --- --- --- --- --- --- --G --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- - | -- L*0102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- - | -- Nuc. Pos. 90 120 150 Prot. Pos. 10 20 L*01010101 TCC CAC TCC TTG AGG TAT TTC AGC ACC GCA GTG TCC CAG CCC GGC CGC GGG GAG CCC CGG TTC ATC GCC GTG GGC L*01010102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- L*01010103 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- L*010102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- L*0102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- Nuc. Pos. 180 210 Prot. Pos. 30 40 50 L*01010101 TAC GTG GAC GAC ACA GAG TTC GTG CGG TTC GAC AGC GAC TCC GTG AGT CCG AGG ATG GAG CGG CGG GCG CCG TGG L*01010102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- L*01010103 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- L*010102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- L*0102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- Nuc. Pos. 240 270 300 Prot. Pos. 60 70 L*01010101 GTG GAG CAG GAG GGG CTG GAG TAT TGG GAC CAG GAG ACA CGG AAC GCC AAG GGC CAC GCG CAG ATT TAC CGA GTG L*01010102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- L*01010103 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- L*010102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- L*0102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- Nuc. Pos. 330 360 Prot. Pos. 80 90 100 L*01010101 AAC CTG CGG ACC CTG CTC CGC TAT TAC AAC CAG AGC GAG GCC G | GT TCT CAC ACC ATC CAG AGG AAG CAT GGC TGC L*01010102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- - | -- --- --- --- --- --- --- --- --- --- --- L*01010103 --- --- --- --- --- --- --- --- --- --- --- --- --- --- - | -- --- --- --- --- --- --- --- --- --- --- L*010102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- - | -- --- --- --- --- --- --- --- --- --- --- L*0102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- - | -- --- --- --- --- --- --- --- --- -A- --- Nuc. Pos. 390 420 450 Prot. Pos. 110 120 L*01010101 GAC GTG GGC CCG ACA GGC GCC TCC TCC GCA GGT ATG AAC AGT TCG CCT ACG ATG GCA AGG ATT ACA TCG CCC TGA L*01010102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- L*01010103 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- L*010102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- L*0102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- Nuc. Pos. 480 510 Prot. Pos. 130 140 150 L*01010101 ACG AGG ACC TGC ACT CCT GGA CCG CCG CGA ACA CAG CGG CTC AGA TCT CCC AGC ACA AGT GGG AAG CGG ACA AAT L*01010102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- L*01010103 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- L*010102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- L*0102 --- --- --- --- C-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- Nuc. Pos. 540 570 600 Prot. Pos. 160 170 L*01010101 ACT CAG AGC AGG TCA GGG CCT ACC TGA GGG CAA GTG CAT GGA GTG GCT CCG CAG ACA CCT GGA GAA CGG GAA GGA L*01010102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- L*01010103 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- L*010102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- L*0102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- Nuc. Pos. 630 660 I Prot. Pos. 180 190 200 I L*01010101 GAC GCT GCA GCA CGC GG | A TCC CCC AAA GGC ACA TGT GAC CCA GCA CCC CAT CTC TGA CCA TGA GGC CAC CCT . L*01010102 --- --- --- --- --- -- | - --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- . L*01010103 --- --- --- --- --- -- | - --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- . L*010102 --- --- --- --- --- -- | - --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- . L*0102 --- --- --- --G --- -- | - --- --- --- --- --- --- --- --- --- --- -G- --- --- --- --- --- --- --- T Nuc. Pos. 690 720 Prot. Pos. 210 220 L*01010101 GAG GTG CTG GGC CCT GGG CCT CTA CCC TGC GGA GAT CAC ACT GAC CTG GCA GCA GGA TGG GGA GGA CCA GAC CCA L*01010102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- L*01010103 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- L*010102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- L*0102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- Nuc. Pos. 750 780 810 Prot. Pos. 230 240 250 L*01010101 GGA CAC GGA GCT TGT GGA GAC CAG GCC TGC AGG GGA CGG AAC CTT CCA GAA GTG GGT GGC TGT AGT GGT GCC TTC L*01010102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- L*01010103 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- L*010102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- L*0102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- Nuc. Pos. 840 870 Prot. Pos. 260 270 L*01010101 CGG AGA GGA GCA GAG ATA CAT GTG CCA TGT GCA GCA TGA GGG GCT GCC AGA GCC CCT CAC CCT GAG ATG GG | A GCC L*01010102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -- | - --- L*01010103 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -- | - --- L*010102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -- | - --- L*0102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -- | - --- Nuc. Pos. 900 930 960 Prot. Pos. 280 290 300 L*01010101 GTC TTC TCA GCC CAC CAT CCC CAT CGT GGG CAT CGT TGC TGG CCT GTT TCT CCT TGG AGC TGT GGT CAC TGG AGC L*01010102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- L*01010103 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- L*010102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- L*0102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- Nuc. Pos. 990 1020 Prot. Pos. 310 320 L*01010101 TGT GGT TGC TGC TGC GAT GTG GAG GAA GAA AAG CTC AG | A TAG AAC AAG GAG GAG CTA TGC TCG GGC TGC CT | G CAG L*01010102 --- --- --- --- --- --- --- --- --- --- --- --- -- | - --- --- --- --- --- --- --- --- --- --- -- | - --- L*01010103 --- --- --- --- --- --- --- --- --- --- --- --- -- | - --- --- --- --- --- --- --- --- --- --- -- | - --- L*010102 --- --- --- --- --- --- --- --- --- --- --- --- -- | - --- --- --- --- --- --- --- --- --- --- -- | - --- L*0102 --- --- --- --- --T --- --A --- --- --- --- --- -- | - -G- --- --- --- ... --- --- --- --- --- -- | - --- Nuc. Pos. 1050 1080 Prot. Pos. 330 340 L*01010101 CAA TTG TGC TCA GTA CTC TGA TGC ATC TCA TGA TAC TTG TAA AG | C TTG L*01010102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- -- | - --- L*01010103 --- --- --- --- --- --- --- --- --- --- --- --- --- --- -- | - --- L*010102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- -- | - --- L*0102 --- --- --- C-- --- --- --- --- --- --- --- --- --- --- -- | - ---