HLADB-2.28.0-January 2010
HLA-G Protein Sequence Alignments
Sequences Aligned: 15 January 2010
Steven G. E. Marsh, Anthony Nolan Research Institute.


Prot. Pos.        -30        -20        -10        
G*01010101              MVVM APRTLFLLLS GALTLTETWA 
G*01010102              ---- ---------- ---------- 
G*01010103              ---- ---------- ---------- 
G*01010104              ---- ---------- ---------- 
G*01010105              ---- ---------- ---------- 
G*01010106              ---- ---------- ---------- 
G*01010201              ---- ---------- ---------- 
G*01010202              ---- ---------- ---------- 
G*01010301              ---- ---------- ---------- 
G*01010302              ---- ---------- ---------- 
G*010104                **** ********** ********** 
G*010105                **** ********** ********** 
G*010106                ---- ---------- ---------- 
G*010107                **** ********** ********** 
G*010108                ---- ---------- ---------- 
G*010109                ---- ---------- ---------- 
G*010111                ---- ---------- ---------- 
G*010112                ---- ---------- ---------- 
G*010113                **** ********** ********** 
G*010114                **** ********** ********** 
G*010115                **** ********** ********** 
G*010116                **** ********** ********** 
G*010117                **** ********** ********** 
G*010118                **** ********** ********** 
G*010119                **** ********** ********** 
G*010120                ---- ---------- ---------- 
G*0102                  **** ********** ********** 
G*0103                  ---- ---------- ---------- 
G*010401                ---- ---------- ---------- 
G*010402                **** ********** ********** 
G*010403                ---- ---------- ---------- 
G*010404                ---- ---------- ---------- 
G*010405                **** ********** ********** 
G*0105N                 ---- ---------- ---------- 
G*0106                  ---- ---------- ---------- 
G*0107                  ---- ---------- ---------- 
G*0108                  **** ********** ********** 
G*0109                  **** ********** ********** 
G*0110                  **** ********** ********** 
G*0111                  **** ********** ********** 
G*0112                  **** ********** ********** 
G*0113N                 **** ********** ********** 
G*0114                  **** ********** ********** 
G*0115                  **** ********** ********** 
G*0116                  **** ********** ********** 

Prot. Pos.                10         20         30         40         50         60         70         80         90        100 
G*01010101        GSHSMRYFSA AVSRPGRGEP RFIAMGYVDD TQFVRFDSDS ACPRMEPRAP WVEQEGPEYW EEETRNTKAH AQTDRMNLQT LRGYYNQSEA SSHTLQWMIG 
G*01010102        ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*01010103        ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*01010104        ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*01010105        ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*01010106        ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*01010201        ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*01010202        ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*01010301        ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*01010302        ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010104          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010105          *--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010106          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010107          *--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010108          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010109          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010111          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010112          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010113          *--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010114          *--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010115          *--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010116          *--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010117          *--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010118          *--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010119          *--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010120          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*0102            ---------- ---------- ---------- ---------- ---------- ---R------ ---------- ---------- ---------- ---------- 
G*0103            ---------- ---------- ---------- S--------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010401          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010402          *--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010403          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010404          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010405          *--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*0105N           ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*0106            ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*0107            ---------- --F------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*0108            *--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*0109            *--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*0110            *--------- ---------- ---------- M--------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*0111            *--------- ---------- ---------- M--------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*0112            *--------- ---------- ------H--- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*0113N           *--------- ---------- ---------- ---------- ---------- ---X     
G*0114            *--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------D 
G*0115            *--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*0116            *--------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 

Prot. Pos.               110        120        130        140        150        160        170        180        190        200 
G*01010101        CDLGSDGRLL RGYEQYAYDG KDYLALNEDL RSWTAADTAA QISKRKCEAA NVAEQRRAYL EGTCVEWLHR YLENGKEMLQ RADPPKTHVT HHPVFDYEAT 
G*01010102        ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*01010103        ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*01010104        ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*01010105        ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*01010106        ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*01010201        ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*01010202        ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*01010301        ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*01010302        ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010104          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --******** ********** 
G*010105          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010106          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010107          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010108          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010109          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010111          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010112          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010113          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --******** ********** 
G*010114          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010115          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010116          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010117          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010118          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010119          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010120          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*0102            ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*0103            ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010401          ---------I ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010402          ---------I ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010403          ---------I ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010404          ---------I ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010405          ---------I ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*0105N           ---------- ---------- ---------C APGPQRTLRL RSPSASVRRP MWLNKGEPTW RARAWSGSTD TWRT-X   
G*0106            ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*0107            ---------I ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*0108            ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*0109            ---------- ---------- ---------- ---------- ---------- --------H- ---------- ---------- --******** ********** 
G*0110            ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- --******** ********** 
G*0111            ---------I ---------- ---------- ---------- ---------- ---------- ---------- ---------- --******** ********** 
G*0112            ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*0113N                     
G*0114            ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*0115            ---V-----I ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*0116            ----C----- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 

Prot. Pos.               210        220        230        240        250        260        270        280        290        300 
G*01010101        LRCWALGFYP AEIILTWQRD GEDQTQDVEL VETRPAGDGT FQKWAAVVVP SGEEQRYTCH VQHEGLPEPL MLRWKQSSLP TIPIMGIVAG LVVLAAVVTG 
G*01010102        ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*01010103        ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*01010104        ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*01010105        ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*01010106        ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*01010201        ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*01010202        ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*01010301        ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*01010302        ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010104          ********** ********** ********** ********** ********** ********** ********** ********** ********** ********** 
G*010105          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----****** ********** ********** 
G*010106          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010107          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----****** ********** ********** 
G*010108          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010109          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010111          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----****** ********** ********** 
G*010112          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010113          ********** ********** ********** ********** ********** ********** ********** ********** ********** ********** 
G*010114          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----****** ********** ********** 
G*010115          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----****** ********** ********** 
G*010116          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----****** ********** ********** 
G*010117          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----****** ********** ********** 
G*010118          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----****** ********** ********** 
G*010119          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----****** ********** ********** 
G*010120          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*0102            ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*0103            ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010401          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010402          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----****** ********** ********** 
G*010403          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010404          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*010405          ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----****** ********** ********** 
G*0105N                     
G*0106            ---------- ---------- ---------- ---------- ---------- -------M-- ---------- ---------- ---------- ---------- 
G*0107            ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- ---------- 
G*0108            ---------- --------W- ---------- ---------- ---------- ---------- ---------- ----****** ********** ********** 
G*0109            ********** ********** ********** ********** ********** ********** ********** ********** ********** ********** 
G*0110            ********** ********** ********** ********** ********** ********** ********** ********** ********** ********** 
G*0111            ********** ********** ********** ********** ********** ********** ********** ********** ********** ********** 
G*0112            ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----****** ********** ********** 
G*0113N                     
G*0114            ---------- --------Q- ---------- ---------- ---------- -------M-- ---------- ----****** ********** ********** 
G*0115            ---------- ---------- ---------- ---------- ---------- ---------- ---------- ----****** ********** ********** 
G*0116            ---------- ---------- ---------- ---------- ---------- -------M-- ---------- ----****** ********** ********** 

Prot. Pos.               310        320         
G*01010101        AAVAAVLWRK KSSD         
G*01010102        ---------- ----         
G*01010103        ---------- ----         
G*01010104        ---------- ----         
G*01010105        ---------- ----         
G*01010106        ---------- ----         
G*01010201        ---------- ----         
G*01010202        ---------- ----         
G*01010301        ---------- ----         
G*01010302        ---------- ----         
G*010104          ********** ****         
G*010105          ********** ****         
G*010106          ---------- ----         
G*010107          ********** ****         
G*010108          ---------- ----         
G*010109          ---------- ----         
G*010111          ********** ****         
G*010112          ---------- ----         
G*010113          ********** ****         
G*010114          ********** ****         
G*010115          ********** ****         
G*010116          ********** ****         
G*010117          ********** ****         
G*010118          ********** ****         
G*010119          ********** ****         
G*010120          ---------- ----         
G*0102            ---------- ----         
G*0103            ---------- ----         
G*010401          ---------- ----         
G*010402          ********** ****         
G*010403          ---------- ----         
G*010404          ---------- ----         
G*010405          ********** ****         
G*0105N                     
G*0106            ---------- ----         
G*0107            ---------- ----         
G*0108            ********** ****         
G*0109            ********** ****         
G*0110            ********** ****         
G*0111            ********** ****         
G*0112            ********** ****         
G*0113N                     
G*0114            ********** ****         
G*0115            ********** ****         
G*0116            ********** ****