HLADB-2.28.0-January 2010 HLA-DQB1 Nucleotide Sequence Alignments Sequences Aligned: 15 January 2010 Steven G. E. Marsh, Anthony Nolan Research Institute. Nuc. Pos. 30 60 Prot. Pos. -30 -20 -10 DQB1*050101 ATG TCT TGG AAG AAG TCT TTG CGG ATC CCC GGA GAC CTT CGG GTA GCA ACT GTC ACC TTG ATG CTG GCG ATC CTG DQB1*050102 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*050201 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*050202 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*050301 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*050302 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0504 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0505 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*020101 --- --- --- --A --- G-- --- --- --- --- --- -G- --- --- -C- --- --- --G --- --- --- --- T-- --G --- DQB1*020102 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0202 --- --- --- --A --- G-- --- --- --- --- --- -G- --- --- -C- --- --- --G --- --- --- --- T-- --G --- DQB1*0203 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0204 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0205 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030101 --- --- --- --A --- G-- --- --- --- --- --- -G- --- --- -C- --- --- --T --- --- --- --- --- --G --- DQB1*030102 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030103 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030104 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030201 --- --- --- --- --- G-- --- --- --- --T --- -G- --- --- --- --- --- --G --- --- --- --- --- --G --- DQB1*030202 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030203 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030204 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030302 --- --- --- --- --- G-- --- --- --- --T --- -G- --- --- --- --- --- --G --- --- --- --- --- --G --- DQB1*030303 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0304 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030501 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030502 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030503 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030504 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0306 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0307 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0308 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0309 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0310 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0311 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0312 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0313 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0314 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0315 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0316 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0317 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0318 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0319 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0320 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0321 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0322 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0323 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0324 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0325 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0326 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*040101 --- --- --- --- --- G-- --- --- --- --T --- -G- --- --- --- --- --- --G --- --- --- --- --- --G --- DQB1*040102 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0402 --- --- --- --- --- G-- --- --- --- --T --- -G- --- --- --- --- --- --G --- --- --- --- --- --G --- DQB1*040301 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*040302 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0404 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060101 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060102 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060103 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060104 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060105 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060201 --- --- --- --- --- G-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --G --- DQB1*060202 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060301 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060302 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060401 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060402 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060403 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060501 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060502 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0606 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0607 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060801 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060802 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0609 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0610 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*061101 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*061102 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0612 --- --- --- --- --- G-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --G --- DQB1*0613 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*061401 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*061402 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0615 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0616 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0617 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0618 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0619 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0620 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0621 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0622 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0623 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0624 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0625 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0626N *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0627 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0628 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0629 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0630 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0631 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0632 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0633 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0634 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0635 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0636 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0637 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0638 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0639 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** Nuc. Pos. 90 120 150 Prot. Pos. -1 1 10 DQB1*050101 AGC TCC TCA CTG GCT GAG GGC AGA GAC TCT CCC G | AG GAT TTC GTG TAC CAG TTT AAG GGC CTG TGC TAC TTC ACC DQB1*050102 *** *** *** *** *** *** *** *** *** **- --- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*050201 --- --- --- --- --- --- --- --- --- --- --- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*050202 *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *-- --- --- --- --- --- --- --- --- --- --- DQB1*050301 *** *** *** *** *** *** *** --- --- --- --- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*050302 *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0504 *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** --- --- --- --- --- --- --- --- --- --- DQB1*0505 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*020101 --- A-- C-- G-- --- --- --- --- --- --- --- - | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*020102 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*0202 --- A-- C-- G-- --- --- --- --- --- --- --- - | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*0203 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*0204 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*0205 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*030101 --- A-- C-- G-- --- --- --- --- --- --- --- - | -- --- --- --- --- --- --- --- -C- A-- --- --- --- --- DQB1*030102 *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *-- --- --- --- --- -C- A-- --- --- --- --- DQB1*030103 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- -C- A-- --- --- --- --- DQB1*030104 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- -C- A-- --- --- --- --- DQB1*030201 --- A-- C-G G-- --- --- --- --- --- --- --- - | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*030202 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*030203 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*030204 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*030302 --- A-- C-G G-- --- --- --- --- --- --- --- - | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*030303 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*0304 *** *** *** *** *** *** *** --- --- --- --- - | -- --- --- --- --- --- --- --- -C- A-- --- --- --- --- DQB1*030501 *** *** *** *** *** *** *** *** *** *** *** - | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*030502 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*030503 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*030504 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*0306 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*0307 *** *** *** *** *** *** *** *** *** *** *** - | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*0308 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*0309 *** *** *** *** *** *** *** --- --- --- --- - | -- --- --- --- --- --- --- --- -C- A-- --- --- --- --- DQB1*0310 *** *** *** *** *** *** *** --- --- --- --- - | -- --- --- --- --- --- --- --- -C- A-- --- --- --- --- DQB1*0311 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*0312 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- -C- A-- --- --- --- --- DQB1*0313 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- -C- A-- --- --- --- --- DQB1*0314 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- -C- A-- --- --- --- --- DQB1*0315 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*0316 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- -C- A-- --- --- --- --- DQB1*0317 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*0318 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*0319 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- -C- A-- --- --- --- --- DQB1*0320 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*0321 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- -C- A-- --- --- --- --- DQB1*0322 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- -C- A-- --- --- --- --- DQB1*0323 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*0324 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- -C- A-- --- --- --- --- DQB1*0325 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*0326 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*040101 --- G-- C-G G-- --- --- --- --- --- --- --- - | -- --- --- --- -T- --- --- --- --- A-- --- --- --- --- DQB1*040102 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- -T- --- --- --- --- A-- --- --- --- --- DQB1*0402 --- A-- C-G G-- --- --- --- --- --- --- --- - | -- --- --- --- -T- --- --- --- --- A-- --- --- --- --- DQB1*040301 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- -T- --- --- --- --- A-- --- --- --- --- DQB1*040302 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- -T- --- --- --- --- A-- --- --- --- --- DQB1*0404 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*060101 *** *** *** *** *** *** *** --- --- C-- --- - | -- --- --- --- CT- --- --- --- -C- A-- --- --- --- --- DQB1*060102 *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** *** *** *** -C- A-- --- --- --- --- DQB1*060103 *** *** *** *** *** *** *** --- --- C-- --- - | -- --- --- --- CT- --- --- --- -C- A-- --- --- --- --- DQB1*060104 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- CT- --- --- --- -C- A-- --- --- --- --- DQB1*060105 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- CT- --- --- --- -C- A-- --- --- --- --- DQB1*060201 --- --- CT- --- --- --- --- --- --- --- --- - | -- --- --- --- -T- --- --- --- --- A-- --- --- --- --- DQB1*060202 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- -T- --- --- --- --- A-- --- --- --- --- DQB1*060301 *** *** *** *** *** *** *** --- --- --- --- - | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*060302 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*060401 *** *** *** *** *** *** *** --- --- --- --- - | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*060402 *** *** *** *** *** *** *** *** *** --- --- - | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*060403 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*060501 *** *** *** *** *** *** *** --- --- --- --- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*060502 *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0606 *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0607 *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** --- --- --- --- --- A-- --- --- --- --- DQB1*060801 *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** --- --- --- --- --- A-- --- --- --- --- DQB1*060802 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*0609 *** *** *** *** *** *** *** --- --- --- --- - | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*0610 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- -T- --- --- --- --- A-- --- --- --- --- DQB1*061101 *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *-- --- --- --- --- --- A-- --- --- --- --- DQB1*061102 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*0612 --- --- CT- --- --- --- --- --- --- --- --- - | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*0613 *** *** *** *** *** *** *** *** *** *** *** - | -- --- --- --- -T- --- --- --- --- A-- --- --- --- --- DQB1*061401 *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *-- -T- --- --- --- --- A-- --- --- --- --- DQB1*061402 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- -T- --- --- --- --- A-- --- --- --- --- DQB1*0615 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- -T- --- --- --- --- A-- --- --- --- --- DQB1*0616 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- -T- --- --- --- --- A-- --- --- --- --- DQB1*0617 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*0618 *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *-- --- --- --- --- --- A-- --- --- --- --- DQB1*0619 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- -T- --- --- --- --- A-- --- --- --- --- DQB1*0620 *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** -T- --- --- --- --- --- --- --- --- --- DQB1*0621 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*0622 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- -T- --- --- --- --- A-- --- --- --- --- DQB1*0623 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- -T- --- --- --- --- A-- --- --- --- --- DQB1*0624 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- -T- --- --- --- --- A-- --- --- --- --- DQB1*0625 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*0626N *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*0627 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*0628 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*0629 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- -T- --- --- --- --- A-- --- --- --- --- DQB1*0630 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*0631 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*0632 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*0633 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- -T- --- --A --- --- A-- --- --- --- --- DQB1*0634 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*0635 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- CT- --- --- --- -C- A-- --- --- --- --- DQB1*0636 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*0637 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- -T- --- --- --- --- A-- --- --- --- --- DQB1*0638 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- DQB1*0639 *** *** *** *** *** *** *** *** *** *** *** * | -- --- --- --- --- --- --- --- --- A-- --- --- --- --- Nuc. Pos. 180 210 Prot. Pos. 20 30 40 DQB1*050101 AAC GGG ACG GAG CGC GTG CGG GGT GTG ACC AGA CAC ATC TAT AAC CGA GAG GAG TAC GTG CGC TTC GAC AGC GAC DQB1*050102 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*050201 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*050202 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*050301 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*050302 *** **- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*0504 --- --- --- --- --- --- --- --- --- --- --- T-- --- --- --- --- --A --- --- --- --- --- --- --- --- DQB1*0505 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*020101 --- --- --A --- --- --- --T CT- --- -G- --- AG- --- --- --- --- --A --- AT- --- --- --- --- --- --- DQB1*020102 --- --- --A --- --- --- --T CT- --- -G- --- AG- --- --- --- --- --A --- AT- --- --- --- --- --- --- DQB1*0202 --- --- --A --- --- --- --T CT- --- -G- --- AG- --- --- --- --- --A --- AT- --- --- --- --- --- --- DQB1*0203 --- --- --A --- --- --- --T CT- --- -G- --- AG- --- --- --- --- --A --- AT- --- --- --- --- --- --- DQB1*0204 --- --- --A --- --- --- --T CT- --- -G- --- AG- --- --- --- --- --A --- AT- --- --- --- --- --- --- DQB1*0205 --- --- --A --- --- --- --T CT- --- -G- --- AG- --- --- --- --- --A --- AT- --- --- --- --- --- --- DQB1*030101 --- --- --- --- --- --- --T TA- --- --- --- T-- --- --- --- --- --- --- --- -CA --- --- --- --- --- DQB1*030102 --- --- --- --- --- --- --T TA- --- --- --- T-- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*030103 --- --- --- --- --- --- --T TA- --- --- --- T-- --- --- --- --- --- --- --- -CA --- --- --- --- --- DQB1*030104 --- --- --- --- --- --- --T TA- --- --- --- T-- --- --- --- --- --- --- --- -CA --- --- --- --- --- DQB1*030201 --- --- --- --- --- --- --T CT- --- --- --- T-- --- --- --- --- --- --- --- -CA --- --- --- --- --- DQB1*030202 --- --- --- --- --- --- --T CT- --- --- --- T-- --- --- --- --- --- --- --- -CA --- --- --- --- --- DQB1*030203 --- --- --- --- --- --- --T CT- --- --- --- T-- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*030204 --- --- --- --- --- --- --T CT- --- --- --- T-- --- --- --T --- --- --- --- -CA --- --- --- --- --- DQB1*030302 --- --- --- --- --- --- --T CT- --- --- --- T-- --- --- --- --- --- --- --- -CA --- --- --- --- --- DQB1*030303 --- --- --- --- --- --- --T CT- --- --- --- T-- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*0304 --- --- --- --- --- --- --T TA- --- --- --- T-- --- --- --- --- --- --- --- -CA --- --- --- --- --- DQB1*030501 --- --- --C --- --- --- --- --- --- --- --- T-- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*030502 --- --- --- --- --- --- --- --- --- --- --- T-- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*030503 --- --- --C --- --- --- --- --- --- --- --- T-- --- --- --- --- --- --- --- -CA --- --- --- --- --- DQB1*030504 --- --- --- --- --- --- --- --- --- --- --- T-- --- --- --- --- --- --- --- -CA --- --- --- --- --- DQB1*0306 --- --- --- --- --- --- --T CT- --- --- --- T-- --- --- --- --- --- --- --- -CA --- --- --- --- --- DQB1*0307 --- --- --- --- --- --- --T CT- --- --- --- T-- --- --- --- --- --- --- --- -CA --- --- --- --- --- DQB1*0308 --- --- --- --- --- --- --T CT- --- --- --- T-- --- --- --- --- --- --- --- -CA --- --- --- --- --- DQB1*0309 --- --- --- --- --- --- --T TA- --- --- --- T-- --- --- --- --- --- --- --- -CA --- --- --- --- --- DQB1*0310 --- --- --- --- --- --- --T TA- --- --- --- T-- --- --- --- --- --- --- --- -CA --- --- --- --- --- DQB1*0311 --- --- --- --- --- --- --T CT- --- --- --- T-- --- --- --- --- --- --- --- -CA --- --- --- --- --- DQB1*0312 --- --- --- --- --- --- --T CT- --- --- --- T-- --- --- --- --- --- --- --- -CA --- --- --- --- --- DQB1*0313 --- --- --- --- --- --- --T TA- --- --- --- T-- --- --- --- --- --- --- --- -CA --- --- --- --- --- DQB1*0314 --- --- --- --- --- --- --T TA- --- --- --- T-- --- --- --- --- --- --- --- -CA --- --- --- --- --- DQB1*0315 --- --- --- --- --- --- --T CT- --- --- --- T-- --- --- --- --- --- --- --- -CA --- --- --- --- --- DQB1*0316 --- --- --- --- --- --- --T TA- --- --- --- T-- --- --- --- --- --- --- --- -CA --- --- --- --- --- DQB1*0317 --- --- --C --- --- --- --- --- --- --- --- T-- --- --- --- --- --- --- --- -CA --- --- --- --- --- DQB1*0318 --- --- --- --- --- --- --T CT- C-- --- --- T-- --- --- --- --- --- --- --- -CA --- --- --- --- --- DQB1*0319 --- --- --- --- --- --- --T TA- --- --- --- T-- --- --- --- --- --- --- --- -CA --- --- --- --- --- DQB1*0320 --- --- --- --- --- --- --T CT- --- --- --- T-- --- --- --- --- --- --- --- ACA --- --- --- --- --- DQB1*0321 --- --- --- --- --- --- --T TA- --- --- --- T-- --- --- --- --- --- --- --- -CA --- --- --- --- --- DQB1*0322 --- --- --- --- --- --- --T TA- --- --- --- T-- --- --- --- --- --- --- --- -CA --- --- --- --- --- DQB1*0323 --- --- --- --- --- --- --T CT- --- --- --- T-- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*0324 --- --- --- --- --- --- --T TA- --- --- --- T-- --- --- --- --- --- --- --- -CA --- --- --- --- --- DQB1*0325 --- --- --- --- --- --- --T CT- --- --- --- T-- --- --- --- --- --- --- --- -CA --- --- --- --- --- DQB1*0326 --- --- --- --- --- --- --T CT- --- --- --- T-- --- --- --- --- --- --- --- -CA --- --- --- --- --- DQB1*040101 --- --- --C --- -T- --- --- --- --- --- --- T-- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*040102 --- --- --C --- -T- --- --- --- --- --- --- T-- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*0402 --- --- --C --- --- --- --- --- --- --- --- T-- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*040301 --- --- --C --- --- --- --T CT- --- --- --- T-- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*040302 --- --- --- --- --- --- --T CT- --- --- --- T-- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*0404 --- --- --C --- --- --- --- --- --- --- --- T-- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*060101 --T --- --- --- --- --- --T TA- --- --- --- T-- --- --- --- --- --- --- G-- --- --- --- --- --- --- DQB1*060102 --- --- --- --- --- --- --T TA- --- --- --- T-- --- --- --- --- --- --- G-- --- --- --- --- --- --- DQB1*060103 --T --- --- --- --- --- --T TA- --- --- --- T-- --- --- --- --- --- --- G-- --- --- --- --- --- --- DQB1*060104 --T --C --- --- --- --- --T TA- --- --- --- T-- --- --- --- --- --- --- G-- --- --- --- --- --- --- DQB1*060105 --T --- --- --- --- --- --T TA- --- --- --- T-- --- --- --- --- --- --- G-- --- --- --- --- --- --- DQB1*060201 --- --- --- --- --- --- --T CT- --- --- --- T-- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*060202 --- --- --- --- --- --- --T CT- --- --- --- T-- --- --- --- --- --- --- --- -CA --- --- --- --- --- DQB1*060301 --- --- --- --- --- --- --T CT- --A --- --- --- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*060302 --- --- --- --- --- --- --T CT- --A --- --- --- --- --- --- --- --- --- --- -CA --- --- --- --- --- DQB1*060401 --- --- --- --- --- --- --T CT- --A --- --- --- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*060402 --- --- --- --- --- --- --T CT- --A --- --- --- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*060403 --- --- --- --- --- --- --T CT- --A --- --- --- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*060501 --- --- --- --- --- --- --T CT- --A --- --- T-- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*060502 *** *-- --- --- --- --- --T CT- --A --- --- T-- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*0606 *** *-- --- --- --- --- --T CT- --A --- --- T-- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*0607 --- --- --- --- --- --- --T CT- --A --- --- --- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*060801 --- --- --- --- --- --- --T CT- --A --- --- --- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*060802 --- --- --- --- --- --- --T CT- --A --- --- --- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*0609 --- --- --- --- --- --- --T CT- --A --- --- T-- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*0610 --- --- --- --- --- --- --T CT- --- --- --- T-- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*061101 --- --- --- --- --- --- --T CT- --- --- --- T-- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*061102 --- --- --- --- --- --- --T CT- --A --- --- T-- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*0612 --- --- --- --- --- --- --T CT- --A --- --- T-- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*0613 --- --- --- --- --- --- --T CT- --- --- --- T-- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*061401 --- --- --- --- --- --- --T CT- --A --- --- --- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*061402 --- --- --- --- --- --- --T CT- --- --- --- --- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*0615 --- --- --- --- --- --- --T CT- --- --- --- T-- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*0616 --- --- --- --- --- --- --T CT- --- --- --- T-- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*0617 --- --- --- --- --- --- --T CT- --A --- --- --- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*0618 --- --- --- --- --- --- --T CT- --A --- --- T-- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*0619 --- --- --- --- --- --- --T CT- --- --- --- T-- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*0620 --- --- --- --- --- --- --T CT- --- --- --- T-- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*0621 --- --- --- --- --- --- --T CT- --A --- --- --- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*0622 --- --- --- --- --- --- --T CT- --- --- --- T-- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*0623 --- --- --- --- --- --- --- --- --- --- --- T-- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*0624 --- --- --- --- --- --- --T CT- --- --- --- T-- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*0625 --- --- --- --- --- --- --T CT- --A --- --- --- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*0626N --- --- --- --- --- --- --T CT- --A --- T-- --- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*0627 --- --- --- --- --- --- --T CT- --A --- --- --- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*0628 --- --- --- --- --- --- --T CT- --A --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*0629 --- --- --- --- --- --- --T CT- --- --- --- T-- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*0630 --- --- --- --- --- --- --T CT- --A --- --- --- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*0631 --- --- --- --- --- --- --T CT- --A --- --- --- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*0632 --- --- --- --- --- --- --T CT- --A --- --- --- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*0633 --- --- --- --- --- --- --T CT- --- --- --- T-- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*0634 --- --- --- --- --- --- --T CT- --A --- --- --- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*0635 --T --- --- --- --- --- --T TA- --- --- --- T-- --- --- --- --- --- --- G-- --- --- --- --- --- --- DQB1*0636 --- --- --- --- --- --- --T CT- --A --- --- --- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*0637 --- --- --- --- --- --- --T CT- --- --- --- T-- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*0638 --- --- --- --- --- --- --T CT- --A --- --- --- --- --- --- --- --- --- --- -C- --- --- --- --- --- DQB1*0639 --- --- --- --- --- --- --T CT- --A --- --- --- --- --- --- --- --- --- --- -C- --- --- --- --- --- Nuc. Pos. 240 270 300 Prot. Pos. 50 60 DQB1*050101 GTG GGG GTG TAC CGG GCA GTG ACG CCG CAG GGG CGG CCT GTT GCC GAG TAC TGG AAC AGC CAG AAG GAA GTC CTG DQB1*050102 --- --- --- --- --- --G --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*050201 --- --- --- --- --- --G --- --- --- --- --- --- --- AGC --- --- --- --- --- --- --- --- --- --- --- DQB1*050202 --- --- --- --T --- --G --- --- --- --- --- --- --- AGC --- --- --- --- --- --- --- --- --- --- --- DQB1*050301 --- --- --- --T --- --G --- --- --- --- --- --- --- -AC --- --- --- --- --- --- --- --- --- --- --- DQB1*050302 --- --- --- --T --- --G --- --- --- --- --- --- --- -A- --- --- --- --- --- --- --- --- --- --- --- DQB1*0504 --- --- --- --- --- --G --- --- --- --- --- --- --- AGC --- --- --- --- --- --- --- --- --C A-- --- DQB1*0505 --- --- --- --- --- --G --- --- --- --- --- --- --- AGC --- --- --- --- --- --- --- --- --- --- --- DQB1*020101 --- --- -A- -T- --- --G --- --- -T- -T- --- -T- --- -CC --- --- --- --- --- --- --- --- --C A-- --- DQB1*020102 --- --- -A- -T- --- --G --- --- -T- -T- --- -T- --- -CC --- --- --T --- --- --- --- --- --C A-- --- DQB1*0202 --- --- -A- -T- --- --G --- --- -T- -T- --- -T- --- -CC --- --- --- --- --- --- --- --- --C A-- --- DQB1*0203 --- --- -A- -T- --- --G --- --- -T- -T- --- -T- --- -AC --- --- --- --- --- --- --- --- --C A-- --- DQB1*0204 --- --- -A- -T- --- --G --- --- -T- -T- --- -T- --- -CC --- --- --- --- --- --- --- --- --C A-- --- DQB1*0205 --- --- -A- -T- --- --G --- --- -T- -T- --- -T- --- -CC --- --- --- --- --- --- --- --- --C A-- --- DQB1*030101 --- -A- --- --- --- --G --- --- --- -T- --- -C- --- -AC --- --- --- --- --- --- --- --- --- --- --- DQB1*030102 --- -A- --- --- --- --G --- --- --- -T- --- -C- --- -AC --- --- --- --- --- --- --- --- --- --- --- DQB1*030103 --- -A- --- --- --- --G --- --- --- -T- --- -CC --- -AC --- --- --- --- --- --- --- --- --- --- --- DQB1*030104 --- -A- --- --- --- --G --- --- --- -T- --- -C- --- -AC --- --- --- --- --- --- --- --- --- --- --- DQB1*030201 --- --- --- --T --- --G --- --- --- -T- --- -C- --- -CC --- --- --- --- --- --- --- --- --- --- --- DQB1*030202 --- --- --- --T --- --G --- --- --- -T- --- -C- --- -CC --- --- --- --- --- --- --- --- --- --- --- DQB1*030203 --- --- --- --T --- --G --- --- --- -T- --- -C- --- -CC --- --- --- --- --- --- --- --- --- --- --- DQB1*030204 --- --- --- --T --- --G --- --- --- -T- --- -C- --- -CC --- --- --- --- --- --- --- --- --- --- --- DQB1*030302 --- --- --- --T --- --G --- --- --- -T- --- -C- --- -AC --- --- --- --- --- --- --- --- --- --- --- DQB1*030303 --- --- --- --T --- --G --- --- --- -T- --- -C- --- -AC --- --- --- --- --- --- --- --- --- --- --- DQB1*0304 --- -A- --- --- --- --G --- --- --- -T- --- -C- --- -CC --- --- --- --- --- --- --- --- --- --- --- DQB1*030501 --- --- --- --T --- --G --- --- --- -T- --- -C- --- -CC --- --- --- --- --- --- --- --- --- --- --- DQB1*030502 --- --- --- --T --- --G --- --- --- -T- --- -C- --- -CC --- --- --- --- --- --- --- --- --- --- --- DQB1*030503 --- --- --- --T --- --G --- --- --- -T- --- -C- --- -CC --- --- --- --- --- --- --- --- --- --- --- DQB1*030504 --- --- --- --T --- --G --- --- --- -T- --- -C- --- -CC --- --- --- --- --- --- --- --- --- --- --- DQB1*0306 --- --- --- --T --- --G --- --- --- -T- --- -C- --- -AC --- --- --- --- --T --- --- --- --C A-- --- DQB1*0307 --- --- --- --T --- -TG --- --- --- -T- --- -C- --- -CC --- --- --- --- --- --- --- --- --- --- --- DQB1*0308 --- --- --- --T --- --G --- --- --- -T- --- -C- --- -CC --- --- --- --- --- --- --- --- --- --- --- DQB1*0309 --- -A- --- --- --- --G --- --- --- -T- --- -C- --- -AC --- --- --- --- --- --- --- --- --- --- --- DQB1*0310 --- --- --- --T --- --G --- --- --- -T- --- -C- --- -AC --- --- --- --- --- --- --- --- --- --- --- DQB1*0311 --- --- --- --T --- --G --- --- --- -T- --- -C- --- -CC --- --- --- --- --- --- --- --- --- --- --- DQB1*0312 --- --- --- --T --- --G --- --- --- -T- --- -C- --- -AC --- --- --- --- --- --- --- --- --- --- --- DQB1*0313 --- -A- --- --- --- --G --- --- --- -T- --- -C- --- -AC --- --- --- --- --- --- --- --- --- -A- --- DQB1*0314 --- --- --- --- --- --G --- --- --- -T- --- -C- --- -CC --- --- --- --- --- --- --- --- --- --- --- DQB1*0315 --- --- --- --T --- --G --- --- --- -T- --- -C- --- -AC --- --- --- --- --- --G --- --- --- --- --- DQB1*0316 --- -A- --- --- --- --G --- --- --- -T- --- -A- --- -AC --- --- --- --- --- --- --- --- --- --- --- DQB1*0317 --- --- --- --T --- --G --- --- --- -T- --- -C- --- -AC --- --- --- --- --- --- --- --- --- --- --- DQB1*0318 --- --- --- --T --- --G --- --- --- -T- --- -C- --- -CC --- --- --- --- --- --- --- --- --- --- --- DQB1*0319 --- -A- --- --- --- --G --- --- --- -T- --- -C- --- -AC --- --- --- --- --- --- --- --- --- --- --- DQB1*0320 --- --- --- --T --- --G --- --- --- -T- --- -C- --- -AC --- --- --- --- --- --- --- --- --- --- --- DQB1*0321 --- -A- --- --- --- --G --- --- --- -T- --- -C- --- -AC --- --- --- --- --- --- --- --- --- --- --- DQB1*0322 --- -A- --- --- --- --G --- --- --- -T- --- -C- --- -AC --- --- --- --- --- --- --- --- --- --- --- DQB1*0323 --- --- --- --- --C --G --- --- --- --- --- --- --- -A- --- --- --- --- --- --- --- --- --- --- --- DQB1*0324 --- -A- --- --- --- --G --- --- --- -T- --- -C- --- -AC --- --- --- --- --- --- --- --- --- --- --- DQB1*0325 --- --- --- --T --- --G --- --- --- -T- --- --- -T- -AC --- --- --- --- --T --- --- --- --C A-- --- DQB1*0326 --- --- --- --T --- --G --- --- --- -T- --- -C- --- -AC --- --- --- --- --- --- --- --- --- --- --- DQB1*040101 --- --- --- --T --- --G --- --- --- -T- --- --- -T- -AC --- --- --- --- --T --- --- --- --C A-- --- DQB1*040102 --- --- --- --T --- --G --- --- --- -T- --- --- -T- -AC --- --- --- --- --T --- --- --- --C A-- --- DQB1*0402 --- --- --- --T --- --G --- --- --- -T- --- --- -T- -AC --- --- --- --- --T --- --- --- --C A-- --- DQB1*040301 --- --- --- --T --- --G --- --- --- -T- --- --- -T- -AC --- --- --- --- --T --- --- --- --C A-- --- DQB1*040302 --- --- --- --T --- --G --- --- --- -T- --- --- -T- -AC --- --- --- --- --T --- --- --- --C A-- --- DQB1*0404 --- --- --- --T --- --G --- --- --- -T- --- --- -T- -AC --- --- --- --- --T --- --- --- --C A-- --- DQB1*060101 --- --- --- --T --- --G --- --- --- --- --- --- --- -AC --- --- --- --- --- --- --- --- --C A-- --- DQB1*060102 --- --- --- --T --- --G --- --C --- --- --- --- --- -AC --- --- --- --- --- --- --- --- --C A-- --- DQB1*060103 --- --- --- --T --- --G --- --- --- --- --- --- --- -AC --- --- --- --- --- --- --- --- --C A-- --- DQB1*060104 --- --- --- --T --- --G --- --- --- --- --- --- --- -AC --- --- --- --- --- --- --- --- --C A-- --- DQB1*060105 --- --- --- --T --- --G --- --- --- --- --- --- --- -AC --- --- --- --- --- --- --- --- --C A-- --- DQB1*060201 --- --- --- --- --C --G --- --- --- --- --- --- --- -A- --- --- --- --- --- --- --- --- --- --- --- DQB1*060202 --- --- --- --- --C --G --- --- --- --- --- --- --- -A- --- --- --- --- --- --- --- --- --- --- --- DQB1*060301 --- --- --- --- --C --G --- --- --- --- --- --- --- -A- --- --- --- --- --- --- --- --- --- --- --- DQB1*060302 --- --- --- --- --C --G --- --- --- --- --- --- --- -A- --- --- --- --- --- --- --- --- --- --- --- DQB1*060401 --- --- --- --- --- --G --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*060402 --- --- --- --- --C --G --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*060403 --- --- --- --- --- --G --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*060501 --- --- --- --- --- --G --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*060502 --- --- --- --- --- --G --- --- --- --- --- --- --- --C --- --- --- --- --- --- --- --- --- --- --- DQB1*0606 --- --- --- --- --- --G --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*0607 --- --- --- --- --C --G --- --- --- --- --- --- --- -A- --- --- --- --- --- --- --- --- --- --- --- DQB1*060801 --- --- --- --- --C --G --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*060802 --- --- --- --- --- --G --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*0609 --- --- --- --- --- --G --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*0610 --- --- --- --- --C --G --- --- --- --- --- --- --- AGC --- --- --- --- --- --- --- --- --- --- --- DQB1*061101 --- --- --- --- --C --G --- --- --- --- --- --- --- -A- --- --- --- --- --- --- --- --- --- --- --- DQB1*061102 --- --- --- --- --C --G --- --- --- --- --- --- --- -A- --- --- --- --- --- --- --- --- --- --- --- DQB1*0612 --- --- --- --- --- --G --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*0613 --- --- --- --- --C --G --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*061401 --- --- --- --- --C --G --- --- --- --- --- --- --- -A- --- --- --- --- --- --- --- --- --- --- --- DQB1*061402 --- --- --- --- --C --G --- --- --- --- --- --- --- -A- --- --- --- --- --- --- --- --- --- --- --- DQB1*0615 --- --- --- --- --C --G --- --- --- --- --- --- --- -A- --- --- --- --- --- --- --- --- --- --- --- DQB1*0616 --- --- --- --- --C --G --- --- --- --- --- --- --- -A- --- --- A-- --- --- --- --- --- --- --- --- DQB1*0617 --- --- --- --- --- --G --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*0618 --- --- --- --- --- --G --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*0619 --- --- --- --T --- --G --- --- --- -T- --- --- --- -A- --- --- --- --- --- --- --- --- --- --- --- DQB1*0620 --- --- --- --- --C --G --- --- --- --- --- --- --- -A- --- --- --- --- --- --- --- --- --- --- --- DQB1*0621 --- --- --- --- --- --G --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*0622 --- --- --- --- --- --G --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*0623 --- --- --- --- --C --G --- --- --- --- --- --- --- -A- --- --- --- --- --- --- --- --- --- --- --- DQB1*0624 --- --- --- --- --C --G --- --- --- --- --- --- --- -A- --- --- --- --- --- --- --- --- --- --- --- DQB1*0625 --- --- --- --- --- --G --- --- --- --- --- --- --- AGC --- --- --- --- --- --- --- --- --- --- --- DQB1*0626N --- --- --- --- --C --G --- --- --- --- --- --- --- -A- --- --- --- --- --- --- --- --- --- --- --- DQB1*0627 --- --- --- --- --- --G --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*0628 --- --- --- --- --C --G --- --- --- --- --- --- --- -A- --- --- --- --- --- --- --- --- --- --- --- DQB1*0629 --- --- --- --- --C --G --- --- --- --- --- -C- --- -CC --- --- --- --- --- --- --- --- --- --- --- DQB1*0630 --- --- --- --- --C --G --- --- --- --- --- --- --- -A- --- --- --- --- --- --- --- --- --- --- --- DQB1*0631 --- --- --- --- --C --G --- --- --- --- --- --- --- -A- --- --- --- --- --- --- --- --- --- --- --- DQB1*0632 --- --- --- --- --C --G --- --- --- --- --- --- --- -A- --- --- --- --- --- --- --- --- --- --- --- DQB1*0633 --- --- --- --- --C --G --- --- --- --- --- --- --- -A- --- --- --- --- --- --- --- --- --- --- --- DQB1*0634 --- --- --- --- --- --G --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*0635 --- -A- --- --- --- --G --- --- --- -T- --- --- --- -AC --- --- --- --- --- --- --- --- --C A-- --- DQB1*0636 --- --- --- --- --- --G --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*0637 --- --- --- --- --C --G --- --- --- --- --- --- --- -A- --- --- --- --- --G --- --- --- --- --- --- DQB1*0638 --- --- --- --- --- --G --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*0639 --- --- --- --- --- --G --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- Nuc. Pos. 330 360 Prot. Pos. 70 80 90 DQB1*050101 GAG GGG GCC CGG GCG TCG GTG GAC AGG GTG TGC AGA CAC AAC TAC GAG GTG GCG TAC CGC GGG ATC CTG CAG AGG DQB1*050102 --- --- --- --- --- --- --- --- --A --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*050201 --- --- --- --- --- --- --- --- --A --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*050202 --- --- --- --- --- --- --- --- --A --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*050301 --- --- --- --- --- --- --- --- --A --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*050302 --- *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0504 --- -A- -A- --- --- --- --- --- --- --- --- --- --- --- -** *** *** *** *** *** *** *** *** *** *** DQB1*0505 --- --- --- --- --- --- --- --- --A --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*020101 --- A-- AAA --- --- G-- --- --- --- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*020102 --- A-- AAA --- --- G-- --- --- --- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*0202 --- A-- AAA --- --- G-- --- --- --- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*0203 --- A-- AAA --- --- G-- --- --- --- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*0204 --- A-- AAA --- --- G-- --- --- --- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*0205 --- A-- AAA --- --- G-- --- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*030101 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*030102 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*030103 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*030104 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*030201 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*030202 --- A-- A-- --- --- GA- C-- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*030203 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*030204 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*030302 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*030303 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*0304 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*030501 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*030502 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*030503 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*030504 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*0306 --- -A- -A- --- --- --- --- --- -CC --A --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*0307 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*0308 --- --- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*0309 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*0310 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*0311 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*0312 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*0313 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*0314 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*0315 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*0316 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*0317 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*0318 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*0319 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*0320 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*0321 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*0322 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*0323 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*0324 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*0325 --- -A- -A- --- --- --- --- --- -CC --A --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*0326 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*040101 --- -A- -A- --- --- --- --- --- -CC --A --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*040102 --- -A- -A- --- --- --- --T --- -CC --A --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*0402 --- -A- -A- --- --- --- --- --- -CC --A --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*040301 --- -A- -A- --- --- --- --- --- -CC --A --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*040302 --- -A- -A- --- --- --- --- --- -CC --A --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*0404 --- -A- -A- --- --- --- --- --- -CC --A --- --- --- --- --- C-- T-- -A- CT- --- AC- -C- T-- --- C-- DQB1*060101 --- A-- A-- --A --- GA- T-- --- -C- --- --- --- --- --- --- --- --- --- -T- --- --- --- T-- --- --- DQB1*060102 --- A-- A-- --A --- GA- T-- --- -C- --- --- --- *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060103 --- A-- A-- --A --- GA- T-- --- -C- --- --- --- --- --- --- --- --- --- -T- --- --- --- T-- --- --- DQB1*060104 --- A-- A-- --A --- GA- T-- --- -C- --- --- --- --- --- --- --- --- --- -T- --- --- --- T-- --- --- DQB1*060105 --- A-- A-- --A --- GA- T-- --- -C- --- --- --- --- --- --- --- --- --- -T- --- --- --- T-- --- --- DQB1*060201 --- --- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- --- -T- --- --- --- T-- --- --- DQB1*060202 --- --- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- --- -T- --- --- --- T-- --- --- DQB1*060301 --- --- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- --- -T- --- --- --- T-- --- --- DQB1*060302 --- --- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- --- -T- --- --- --- T-- --- --- DQB1*060401 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- -G- --- --- --- --- --- --- --- DQB1*060402 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- -G- --- --- --- --- --- --- --- DQB1*060403 --- A-- A-- --- --- GA- T-- --- -CC --- --- --- --- --- --- --- --- -G- --- --- --- --- --- --- --- DQB1*060501 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- -G- --- --- --- --- --- --- --- DQB1*060502 --- A-- A-- --- --- GA- T-- --- -C- *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0606 --- A-- A-- --- --- G-- --- --- --- --- *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0607 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- -G- --- --- --- --- -** *** *** DQB1*060801 --- --- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- --- -T- --- --- --- T** *** *** DQB1*060802 --- --- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- --- -T- --- --- --- T-- --- --- DQB1*0609 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- -G- --- --- --- --- --- --- --- DQB1*0610 --- --- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- --- -T- --- --- --- T-- --- --- DQB1*061101 --- --- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- --- -T- --- --- --- T-- --- --- DQB1*061102 --- --- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- --- -T- --- --- --- T-- --- --- DQB1*0612 --- --- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- -G- --- --- --- --- --- --- --- DQB1*0613 --- --- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- --- -T- --- --- --* *** *** *** DQB1*061401 --- --- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- --- -T- --- --- --- T-- --- --- DQB1*061402 --- --- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- --- -T- --- --- --- T-- --- --- DQB1*0615 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- -G- --- --- --- --- --- --- --- DQB1*0616 --- --- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- --- -T- --- --- --- T-- --- --- DQB1*0617 --- --- --- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- -G- --- --- --- --- --- --- --- DQB1*0618 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- --- -T- --- --- --- T-- --- --- DQB1*0619 --- --- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- --- -T- --- --- --- T-- --- --- DQB1*0620 --- --- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- --- -T- --- *** *** *** *** *** DQB1*0621 --- --- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- -G- --- --- --- --- --- --- --- DQB1*0622 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- -G- --- --- --- --- --- --- --- DQB1*0623 --- --- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- --- -T- --- --- --- T-- --- --- DQB1*0624 --- --- --- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- --- -T- --- --- --- T-- --- --- DQB1*0625 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- -G- --- --- --- --- --- --- --- DQB1*0626N --- --- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- --- -T- --- --- --- T-- --- --- DQB1*0627 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- --- -T- --- --- --- T-- --- --- DQB1*0628 --- --- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- --- -T- --- --- --- T-- --- --- DQB1*0629 --- --- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- --- -T- --- --- --- T-- --- --- DQB1*0630 --- --- --- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- --- -T- --- --- --- T-- --- --- DQB1*0631 --- --- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- --- -T- --- --- --- T-- --- --- DQB1*0632 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- --- -T- --- --- --- T-- --- --- DQB1*0633 --- --- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- --- -T- --- --- --- T-- --- --- DQB1*0634 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- -G- --- --- --- --- --- --- --- DQB1*0635 --- A-- A-- --A --- GA- T-- --- -C- --- --- --- --- --- --- --- --- --- -T- --- --- --- T-- --- --- DQB1*0636 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- -G- --- --- --- --- --- --- --- DQB1*0637 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- --- -T- --- --- --- T-- --- --- DQB1*0638 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- -G- --- --- --- --- --- --- --- DQB1*0639 --- A-- A-- --- --- GA- T-- --- -C- --- --- --- --- --- --- --- --- -G- --- --- --- --- --- --- --- Nuc. Pos. 390 420 450 Prot. Pos. 100 110 DQB1*050101 AGA G | TG GAG CCC ACA GTG ACC ATC TCC CCA TCC AGG ACA GAG GCC CTC AAC CAC CAC AAC CTG CTG ATC TGC TCG DQB1*050102 *** * | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*050201 --- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*050202 -** * | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*050301 --- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*050302 *** * | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0504 *** * | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0505 --- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*020101 C-- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- G-- --- --- DQB1*020102 C-- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0202 C-- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- G-- --- --- DQB1*0203 C-- * | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0204 C-- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- G-- --- --- DQB1*0205 C-- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030101 C-- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- G-- --- --A DQB1*030102 C-- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030103 C-- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030104 C-- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- G-- --- --A DQB1*030201 C-- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- G-- --- --A DQB1*030202 C-- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030203 C-- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030204 C-- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030302 C-- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- G-- --- --A DQB1*030303 C-- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0304 C-- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- G-- --- --A DQB1*030501 C-- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- G-- --- --A DQB1*030502 C-- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030503 C-- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030504 C-- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0306 C-- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0307 C-- * | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0308 C-- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0309 C-- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- G-- --- --A DQB1*0310 C-- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- G-- --- --A DQB1*0311 C-- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0312 C-- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0313 C-- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0314 C-- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0315 C-- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0316 C-- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0317 C-- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0318 C-- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0319 C-- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- G-- --- --A DQB1*0320 C-- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0321 C-- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- G-- --- --A DQB1*0322 C-- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- G-- --- --A DQB1*0323 C-- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0324 C-- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- G-- --- --A DQB1*0325 C-- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- G-- --- --A DQB1*0326 C-- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*040101 C-- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- G-- --- --A DQB1*040102 C-- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0402 C-- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- G-- --- --A DQB1*040301 C-- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*040302 C-- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0404 C-- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060101 --- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- G-- --- --- DQB1*060102 *** * | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060103 --- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- G-- --- --- DQB1*060104 --- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060105 --- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- G-- --- --- DQB1*060201 --- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- G-- --- --- DQB1*060202 --- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060301 --- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- G-- --- --- DQB1*060302 --- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060401 --- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- G-- --- --- DQB1*060402 --- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- *** *** *** *** *** *** *** *** *** *** DQB1*060403 --- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060501 --- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- *** *** *** *** *** *** *** *** *** *** DQB1*060502 *** * | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0606 *** * | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0607 *** * | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060801 *** * | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060802 --- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0609 --- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- G-- --- --- DQB1*0610 --- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*061101 *** * | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*061102 --- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0612 --- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- G-- --- --- DQB1*0613 *** * | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*061401 --- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*061402 --- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0615 --- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0616 --- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0617 --- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0618 --* * | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0619 --- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0620 *** * | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0621 --- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0622 --- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0623 --- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0624 --- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0625 --- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0626N --- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0627 --- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0628 --- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0629 --- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0630 --- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0631 --- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0632 --- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0633 --- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0634 --- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- G-- --- --- DQB1*0635 --- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0636 --- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- G-- --- --- DQB1*0637 --- - | ** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0638 --- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- G-- --- --- DQB1*0639 --- - | -- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- G-- --- --- Nuc. Pos. 480 510 Prot. Pos. 120 130 140 DQB1*050101 GTG ACA GAT TTC TAT CCA AGC CAG ATC AAA GTC CGG TGG TTT CGG AAT GAT CAG GAG GAG ACA GCC GGC GTT GTG DQB1*050102 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*050201 --- --- --- --- --- --- --- --C --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*050202 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*050301 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*050302 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0504 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0505 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*020101 --- --- --- --- --- --- GC- --- --- --- --- --- --- --- --- --- --C --- --- --- --- --T --- --- --- DQB1*020102 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0202 --- --- --- --- --- --- GC- --- --- --- --- --- --- --- --- --- -GC --- --- --- --- --T --- --- --- DQB1*0203 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0204 --- --- --- --- --- --- GC- --- --- --- --- --- --- --- --- --- --C G-- --- --- --- --T --- --- --- DQB1*0205 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030101 --- --- --- --- --- --- GC- --- --- --- --- --- --- --- --- --- --C --- --- --- --- A-- --- --- --- DQB1*030102 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030103 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030104 --- --- --- --- --- --- GC- --- --- --- --- --- --- --- --- --- --C --- --- --- --- A-- --- --- --- DQB1*030201 --- --- --- --- --- --- GC- --- --- --- --- --- --- --- --- --- --C --- --- --- --- A-T --- --- --- DQB1*030202 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030203 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030204 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030302 --- --- --- --- --- --- GC- --- --- --- --- --- --- --- --- --- --C --- --- --- --- A-T --- --- --- DQB1*030303 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0304 --- --- --- --- --- --- GC- --- --- --- --- --- --- --- --- --- --C --- --- --- --- A-- --- --- --- DQB1*030501 --- --- --- --- --- --- GC- --- --- --- --- --- --- --- --- --- --C --- --- --- --- A-T --- --- --- DQB1*030502 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030503 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030504 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0306 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0307 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0308 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0309 --- --- --- --- --- --- GC- --- --- --- --- --- --- --- --- --- --C --- --- --- --- A-- --- --- --- DQB1*0310 --- --- --- --- --- --- GC- --- --- --- --- --- --- --- --- --- --C --- --- --- --- A-- --- --- --- DQB1*0311 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0312 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0313 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0314 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0315 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0316 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0317 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0318 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0319 --- --- --- --- --- --- GC- --- --- --- --- --- --- --- --- --- --C --- --- --- --- A-- --- --- --- DQB1*0320 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0321 --- --- --- --- --- --- GC- --- --- --- --- --- --- --- T-- --- --C --- --- --- --- A-- --- --- --- DQB1*0322 --- --- --- --- --- --- GC- --- --- --- --- -A- --- --- --- --- --C --- --- --- --- A-- --- --- --- DQB1*0323 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0324 --- --- --- --- --- --- GC- --- --- --- --- --- --- --- --- --- --C --- --- --- --- A-- --- --- --- DQB1*0325 --- --- --- --- --- --- GC- --- --- --- --- --- --- --- --- --- --C --- --- --- --- A-T --- --- --- DQB1*0326 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*040101 --- --- --- --- --- --- GC- --- --- --- --- --- --- --- --- --- --C --- --- --- --- A-T --- --- --- DQB1*040102 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0402 --- --- --- --- --- --- GC- --- --- --- --- --- --- --- --- --- --C --- --- --- --- A-T --- --- --- DQB1*040301 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*040302 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0404 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060101 --- --- --- --- --- --- G-- --- --- --- --- --- --- --- --- --- --C --- --- --- --- --T --- --- --- DQB1*060102 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060103 --- --- --- --- --- --- G-- --- --- --- --- --- --- --- --- --- --C --- --A --- --- --T --- --- --- DQB1*060104 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060105 --- --- --- --- --- --- G-- --- --- --- --- --- --- --- --- --- --C --- --- --- --- --T --- --- --- DQB1*060201 --- --- --- --- --- --- G-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*060202 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060301 --- --- --- --- --- --- G-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*060302 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060401 --- --- --- --- --- --- G-- --- --- --- --- -A- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*060402 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060403 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060501 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060502 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0606 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0607 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060801 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060802 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0609 --- --- --- --- --- --- G-- --- --- --- --- -A- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*0610 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*061101 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*061102 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0612 --- --- --- --- --- --- G-- --- --- --- --- -A- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*0613 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*061401 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*061402 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0615 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0616 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0617 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0618 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0619 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0620 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0621 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0622 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0623 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0624 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0625 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0626N *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0627 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0628 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0629 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0630 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0631 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0632 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0633 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0634 --- --- --- --- --- --- G-- --- --- --- --- -A- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*0635 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0636 --- --- --- --- --- --- G-- --- --- --- --- -A- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*0637 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0638 --- --- --- --- --- --- G-- --- --- --- --- -A- --- --- -A- --- --- --- --- --- --- --- --- --- --- DQB1*0639 --- --- --- --- --- --- G-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- Nuc. Pos. 540 570 600 Prot. Pos. 150 160 DQB1*050101 TCC ACC CCC CTC ATT AGG AAC GGT GAC TGG ACC TTC CAG ATC CTG GTG ATG CTG GAA ATG ACT CCC CAG CGT GGA DQB1*050102 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*050201 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*050202 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*050301 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*050302 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0504 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0505 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*020101 --- --- --- --T --- --- --T --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*020102 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0202 --- --- --- --T --- --- --T --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*0203 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0204 --- --- --- --T --- --- --T --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*0205 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030101 --- --- --- --T --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -A- --- DQB1*030102 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030103 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030104 --- --- --- --T --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -A- --- DQB1*030201 --- --- --- --T --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*030202 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030203 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030204 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030302 --- --- --- --T --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*030303 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0304 --- --- --- --T --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -A- --- DQB1*030501 --- --- --- --T --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*030502 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030503 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030504 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0306 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0307 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0308 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0309 --- --- --- --T --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -A- -CC DQB1*0310 --- --- --- --T --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -A- --- DQB1*0311 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0312 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0313 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0314 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0315 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0316 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0317 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0318 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0319 --- --- --- --T --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -A- --- DQB1*0320 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0321 --- --- --- --T --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -A- --- DQB1*0322 --- --- --- --T --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -A- --- DQB1*0323 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0324 --- --- --- --T --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -A- --- DQB1*0325 --- --- --- --T --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*0326 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*040101 --- --- --- --T --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*040102 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0402 --- --- --- --T --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*040301 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*040302 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0404 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060101 --- --- --- --T --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -A- --- DQB1*060102 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060103 --- --- --- --T --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -A- --- DQB1*060104 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060105 --- --- --- --T --- --- --T --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -A- --- DQB1*060201 --- --- --- --T --- --- --T --- --- --- --T --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*060202 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060301 --- --- --- --T --- --- --T --- --- --- --T --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*060302 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060401 --- --- --- --T --- --- --T --- --- --- --T --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*060402 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060403 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060501 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060502 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0606 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0607 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060801 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060802 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0609 --- --- --- --T --- --- --T --- --- --- --T --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*0610 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*061101 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*061102 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0612 --- --- --- --T --- --- --T --- --- --- --T --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*0613 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*061401 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*061402 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0615 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0616 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0617 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0618 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0619 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0620 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0621 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0622 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0623 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0624 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0625 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0626N *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0627 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0628 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0629 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0630 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0631 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0632 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0633 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0634 --- --- --- --T --- --- --T --- --- --- --T --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*0635 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0636 --- --- --- --T --- --- --T --- --- --- --T --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*0637 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0638 --- --- --- --T --- --- --T --- --- --- --T --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*0639 --- --- --- --T --- --- --T --- --- --- --T --- --- --- --- --- --- --- --- --- --- --- --- --- --- Nuc. Pos. 630 660 Prot. Pos. 170 180 190 DQB1*050101 GAT GTC TAC ACC TGC CAC GTG GAG CAC CCC AGC CTC CAG AGC CCC ATC ACC GTG GAG TGG C | GG GCT CAG TCT GAA DQB1*050102 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*050201 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- - | -- --- --- --- --- DQB1*050202 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*050301 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- - | -- --- --- --- --- DQB1*050302 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0504 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0505 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*020101 --C --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- - | -- --- --A --- --- DQB1*020102 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0202 --C --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- - | -- --- --A --- --- DQB1*0203 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0204 --C --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- - | ** *** *** *** *** DQB1*0205 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*030101 --C --- --- --- --- --- --- --- --- --- --- --- --- -A- --- --- --- --- --- --- - | -- --- --- --- --- DQB1*030102 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*030103 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*030104 --- --- --- --- --- --- --- --- --- --- --- --- --- -A- --- --- --- --- --- --- - | ** *** *** *** *** DQB1*030201 --C --- --- --- --- --- --- --- --- --- --- --- --- -A- --- --- -T- --- --- --- - | -- --- --- --- --- DQB1*030202 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*030203 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*030204 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*030302 --C --- --- --- --- --- --- --- --- --- --- --- --- -A- --- --- -T- --- --- --- - | -- --- --- --- --- DQB1*030303 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0304 --C --- --- --- --- --- --- --- --- --- --- --- --- -A- --- --- --- --- --- --- - | -- --- --- --- --- DQB1*030501 --C --- --- --- --- --- --- --- --- --- --- --- --- -A- --- --- -T- --- --- --- - | -- --- --- --- --- DQB1*030502 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*030503 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*030504 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0306 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0307 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0308 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0309 ... --- --- --- --- --- --- --- --- --- --- --- --- -A- --- --- --- --- --- --- - | -- --- --- --- --- DQB1*0310 --C --- --- --- --- --- --- --- --- --- --- --- --- -A- --- --- --- --- --- --- - | -- --- --- --- --- DQB1*0311 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0312 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0313 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0314 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0315 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0316 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0317 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0318 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0319 --C --- --- --- --- --- --- --- --- --- --- --- --- -A- --- --- -T- --- --- --- - | ** *** *** *** *** DQB1*0320 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0321 --C --- --- --- --- --- --- --- --- --- --- --- --- -A- --- --- --- --- --- --- - | ** *** *** *** *** DQB1*0322 --C --- --- --- --- --- --- --- --- --- --- --- --- -A- --- --- --- --- --- --- - | ** *** *** *** *** DQB1*0323 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0324 --C A-- --- --- --- --- --- --- --- --- --- --- --- -A- --- --- --- --- --- --- - | ** *** *** *** *** DQB1*0325 --C --- --- --- --- --- --- --- --- --- --- --- --- -A- --- --- -T- --- --- --- - | ** *** *** *** *** DQB1*0326 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*040101 --C --- --- --- --- --- --- --- --- --- --- --- --- -A- --- --- -T- --- --- --- - | -- --- --- --- --- DQB1*040102 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0402 --C --- --- --- --- --- --- --- --- --- --- --- --- -A- --- --- -T- --- --- --- - | -- --- --- --- --- DQB1*040301 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*040302 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0404 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*060101 --C --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- - | -- --- --- --- --- DQB1*060102 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*060103 --C --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- - | -- --- --- --- --- DQB1*060104 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*060105 --C --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- - | ** *** *** *** *** DQB1*060201 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- - | -- --- --- --- --- DQB1*060202 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*060301 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- - | -- --- --- --- --- DQB1*060302 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*060401 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- - | -- --- --- --- --- DQB1*060402 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*060403 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*060501 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*060502 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0606 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0607 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*060801 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*060802 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0609 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- - | -- --- --- --- --- DQB1*0610 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*061101 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*061102 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0612 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- - | -- --- --- --- --- DQB1*0613 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*061401 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*061402 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0615 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0616 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0617 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0618 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0619 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0620 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0621 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0622 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0623 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0624 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0625 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0626N *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0627 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0628 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0629 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0630 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0631 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0632 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0633 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0634 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- T | -- --- --* *** *** DQB1*0635 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0636 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -C- --- --- - | -- --- --- --- --- DQB1*0637 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** * | ** *** *** *** *** DQB1*0638 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- - | ** *** *** *** *** DQB1*0639 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- - | ** *** *** *** *** Nuc. Pos. 690 720 750 Prot. Pos. 200 210 DQB1*050101 TCT GCC CAG AGC AAG ATG CTG AGT GGC GTT GGA GGC TTC GTG CTG GGG CTG ATC TTC CTT GGG CTT GGC CTT ATC DQB1*050102 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*050201 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*050202 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*050301 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DQB1*050302 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0504 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0505 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*020101 --- --- --- --- --- --- --- --- --- A-- --- --- --- --- --- --- --- --- --- --C --- --G --- --- --- DQB1*020102 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0202 --- --- --- --- --- --- --- --- --- A-- --- --- --- --- --- --- --- --- --- --C --- --G --- --- --- DQB1*0203 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0204 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0205 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030101 --- --- --- --- --- --- --- --- --- A-- --- --- --- --- --- --- --C --- --- --C --- --G --- --- --T DQB1*030102 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030103 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030104 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030201 --- --- --- --- --- --- --- --- --- A-- --- --- --- --- --- --- --- --- --- --C --- --G --- --- --T DQB1*030202 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030203 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030204 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030302 --- --- --- --- --- --- --- --- --- A-- --- --- --- --- --- --- --- --- --- --C --- --G --- --- --T DQB1*030303 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0304 --- --- --- --- --- --- *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030501 --- --- --- --- --- --- *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030502 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030503 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*030504 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0306 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0307 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0308 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0309 --- --- --- --- --- --- --- --- --- A-- --- --- --- --- --- --- --C --- --- --C --- --G --- --- --T DQB1*0310 --- --- --- --- --- --- --- --- --- A-- --- --- --- --- --- --- --C --- --- --C --- --G --- --- --T DQB1*0311 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0312 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0313 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0314 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0315 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0316 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0317 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0318 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0319 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0320 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0321 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0322 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0323 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0324 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0325 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0326 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*040101 --- --- --- --- --- --- --- --- --- A-- --- --- --- --- --- --- --- --- --- --C --- --G --- --- --T DQB1*040102 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0402 --- --- --- --- --- --- --- --- --- A-- --- --- --- --- --- --- --- --- --- --C --- --G --- --- --T DQB1*040301 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*040302 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0404 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060101 --- --- --- -A- --- --- --- --- --- A-- --- --- --- --- --- --- --- --- --- --C --- --G --- --- --- DQB1*060102 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060103 --- --- --- -A- --- --- --- --- --- A-- --- --- --- --- --- --- --- --- --- --C --- --G --- --- --- DQB1*060104 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060105 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060201 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --G --- --- --- DQB1*060202 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060301 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --G --- --- --- DQB1*060302 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060401 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --G --- --- --- DQB1*060402 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060403 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060501 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060502 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0606 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0607 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060801 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*060802 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0609 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --G --- --- --- DQB1*0610 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*061101 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*061102 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0612 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --G --- --- --- DQB1*0613 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*061401 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*061402 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0615 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0616 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0617 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0618 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0619 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0620 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0621 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0622 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0623 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0624 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0625 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0626N *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0627 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0628 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0629 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0630 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0631 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0632 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0633 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0634 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0635 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0636 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --G --- --- --- DQB1*0637 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0638 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** DQB1*0639 *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** *** Nuc. Pos. I 780 Prot. Pos. 220 I 230 DQB1*050101 ATC CGT CAA AGG AGT CGG AAA G | ........................ GG CTT CTG CAC TGA DQB1*050102 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*050201 --- --- --- --- --- --- --- - | ........................ -- --- --- --- --- DQB1*050202 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*050301 --- --- --- --- --- --- --- - | GACCTCAAGGGCCTCCACCAGCAG -- --- --- --- --- DQB1*050302 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0504 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0505 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*020101 --- -A- --C --- --- -A- --- - | ........................ -- --C --- --- --- DQB1*020102 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0202 --- -A- --C --- --- -A- --- - | ........................ -- --C --- --- --- DQB1*0203 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0204 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0205 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*030101 --- -A- --C --- --- -A- --- - | ........................ -- --C --- --- --- DQB1*030102 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*030103 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*030104 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*030201 --- -A- --C --- --- -A- --- - | ........................ -- --C --- --- --- DQB1*030202 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*030203 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*030204 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*030302 --- -A- --C --- --- -A- --- - | ........................ -- --C --- --- --- DQB1*030303 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0304 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*030501 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*030502 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*030503 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*030504 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0306 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0307 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0308 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0309 --- -A- --C --- --- -A- --- - | ........................ -- --C --- --- --- DQB1*0310 --- -A- --C --- --- -A- --- - | ........................ -- --C --- --- --- DQB1*0311 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0312 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0313 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0314 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0315 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0316 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0317 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0318 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0319 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0320 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0321 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0322 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0323 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0324 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0325 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0326 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*040101 --- -A- --C --- --- -A- --- - | ........................ -- --C --- --- --- DQB1*040102 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0402 --- -A- --C --- --- -A- --- - | ........................ -- --C --- --- --- DQB1*040301 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*040302 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0404 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*060101 --- --- --- --- --- -A- --- - | GACCTCAAGGGCCTCCACCAGCAG -- --- --- --- --- DQB1*060102 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*060103 --- --- --- --- --- -A- --- - | ........................ ** *** *** *** *** DQB1*060104 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*060105 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*060201 --- --- --- --- --- -A- --- - | ........................ -- --- --- --- --- DQB1*060202 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*060301 --- --- --- --- --- -A- --- - | ........................ -- --- --- --- --- DQB1*060302 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*060401 --- --- --- --- --- -A- --- - | ........................ -- --- --- --- --- DQB1*060402 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*060403 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*060501 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*060502 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0606 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0607 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*060801 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*060802 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0609 --- --- --- --- --- -A- --- - | ........................ -- --- --- --- --- DQB1*0610 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*061101 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*061102 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0612 --- --- --- --- --- -A- --- - | ........................ -- --- --- --- --- DQB1*0613 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*061401 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*061402 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0615 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0616 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0617 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0618 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0619 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0620 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0621 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0622 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0623 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0624 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0625 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0626N *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0627 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0628 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0629 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0630 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0631 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0632 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0633 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0634 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0635 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0636 --- --- --- --- --- -A- --- - | ........................ ** *** *** *** *** DQB1*0637 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0638 *** *** *** *** *** *** *** * | ........................ ** *** *** *** *** DQB1*0639 *** *** *** *** *** *** *** * | ........................ ** *** *** *** ***