HLA-DOB Nucleotide Sequence Alignments IMGT/HLA Release: 3.7.0 Sequences Aligned: 12 January 2012 Steven GE Marsh, Anthony Nolan Research Institute. Please see http://hla.alleles.org/terms.html for terms of use. cDNA 1 AA codon -26 | DOB*01:01:01:01 ATG GGT TCT GGG TGG GTC CCC TGG GTG GTG GCT CTG CTA GTG AAT CTG ACC CGA CTG GAT TCC TCC ATG ACT CAA DOB*01:01:01:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:01:03 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:01:04 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:03:01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:03:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:02:01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -A- --- --- --- --- --- --- --- DOB*01:02:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -A- --- --- --- --- --- --- --- DOB*01:03 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:04:01:01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:04:01:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:05 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- cDNA 76 AA codon -1 | DOB*01:01:01:01 GGC ACA GAC TCT CCA G|AA GAT TTT GTG ATT CAG GCA AAG GCT GAC TGT TAC TTC ACC AAC GGG ACA GAA AAG GTG DOB*01:01:01:02 --- --- --- --- --- -|-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:01:03 --- --- --- --- --- -|-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:01:04 --- --- --- --- --- -|-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:02 --- --- --- --- --- -|-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:03:01 --- --- --- --- --- -|-- --C --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:03:02 --- --- --- --- --- -|-- --C --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:02:01 --- --- --- --- --- -|-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:02:02 --- --- --- --- --- -|-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:03 --- --- --- --- --- -|-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:04:01:01 --- --- --- --- --- -|-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:04:01:02 --- --- --- --- --- -|-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:05 --- --- --- --- --- -|-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- cDNA 151 AA codon 25 | DOB*01:01:01:01 CAG TTT GTG GTC AGA TTC ATC TTT AAC TTG GAG GAG TAT GTA CGT TTC GAC AGT GAT GTG GGG ATG TTT GTG GCA DOB*01:01:01:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:01:03 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:01:04 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:03:01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:03:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:02:01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:02:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:03 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:04:01:01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:04:01:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:05 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- cDNA 226 AA codon 50 | DOB*01:01:01:01 TTG ACC AAG CTG GGG CAG CCA GAT GCT GAG CAG TGG AAC AGC CGG CTG GAT CTC TTG GAG AGG AGC AGA CAG GCC DOB*01:01:01:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:01:03 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:01:04 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --A --- --- --- --- --- DOB*01:01:03:01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:03:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:02:01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:02:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --A --- --- --- --- --- DOB*01:03 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:04:01:01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:04:01:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:05 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- cDNA 301 AA codon 75 | DOB*01:01:01:01 GTG GAT GGG GTC TGT AGA CAC AAC TAC AGG CTG GGC GCA CCC TTC ACT GTG GGG AGA AAA G|TG CAA CCA GAG GTG DOB*01:01:01:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -|-- --- --- --- --- DOB*01:01:01:03 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -|-- --- --- --- --- DOB*01:01:01:04 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -|-- --- --- --- --- DOB*01:01:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -|-- --- --- --- --- DOB*01:01:03:01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -|-- --- --- --- --- DOB*01:01:03:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -|-- --- --- --- --- DOB*01:02:01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -|-- --- --- --- --- DOB*01:02:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -|-- --- --- --- --- DOB*01:03 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -|-- --- --- --- --- DOB*01:04:01:01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -|-- --- --- --- --- DOB*01:04:01:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -|-- --- --- --- --- DOB*01:05 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -|-- --- --- --- --- cDNA 376 AA codon 100 | DOB*01:01:01:01 ACA GTG TAC CCA GAG AGG ACC CCA CTC CTG CAC CAG CAT AAT CTG CTG CAC TGC TCT GTG ACA GGC TTC TAT CCA DOB*01:01:01:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:01:03 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:01:04 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:03:01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:03:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:02:01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:02:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:03 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:04:01:01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:04:01:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:05 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- cDNA 451 AA codon 125 | DOB*01:01:01:01 GGG GAT ATC AAG ATC AAG TGG TTC CTG AAT GGG CAG GAG GAG AGA GCT GGG GTC ATG TCC ACT GGC CCT ATC AGG DOB*01:01:01:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:01:03 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:01:04 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:03:01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:03:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:02:01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:02:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:03 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:04:01:01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:04:01:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:05 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- cDNA 526 AA codon 150 | DOB*01:01:01:01 AAT GGA GAC TGG ACC TTT CAG ACT GTG GTG ATG CTA GAA ATG ACT CCT GAA CTT GGA CAT GTC TAC ACC TGC CTT DOB*01:01:01:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:01:03 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:01:04 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:03:01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:03:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:02:01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:02:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:03 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:04:01:01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --T --- --- --- DOB*01:04:01:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --T --- --- --- DOB*01:05 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- cDNA 601 AA codon 175 | DOB*01:01:01:01 GTC GAT CAC TCC AGC CTG CTG AGC CCT GTT TCT GTG GAG TGG A|GA GCT CAG TCT GAA TAT TCT TGG AGA AAG ATG DOB*01:01:01:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- -|-- --- --- --- --- --- --- --- --- --- --- DOB*01:01:01:03 --- --- --- --- --- --- --- --- --- --- --- --- --- --- -|-- --- --- --- --- --- --- --- --- --- --- DOB*01:01:01:04 --- --- --- --- --- --- --- --- --- --- --- --- --- --- -|-- --- --- --- --- --- --- --- --- --- --- DOB*01:01:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- -|-- --- --- --- --- --- --- --- --- --- --- DOB*01:01:03:01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- -|-- --- --- --- --- --- --- --- --- --- --- DOB*01:01:03:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- -|-- --- --- --- --- --- --- --- --- --- --- DOB*01:02:01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- -|-- --- --- --- --- --- --- --- --- --- --- DOB*01:02:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- -|-- --- --- --- --- --- --- --- --- --- --- DOB*01:03 --- --- --- --- --- --- --- --- --- --- --- --- --- --- -|-- --- --- --- --- --- --- --- --- --- --- DOB*01:04:01:01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- -|-- --- --- --- --- --- --- --- --- --- --- DOB*01:04:01:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- -|-- --- --- --- --- --- --- --- --- --- --- DOB*01:05 --- --- --- --- --- --- --- --- --- A-- --- --- --- --- -|-- --- --- --- --- --- --- --- --- --- --- cDNA 676 AA codon 200 | DOB*01:01:01:01 CTG AGT GGC ATT GCA GCC TTC CTA CTT GGG CTA ATC TTC CTT CTG GTG GGA ATC GTC ATC CAG CTA AGG GCT CAG DOB*01:01:01:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:01:03 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:01:04 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:03:01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:01:03:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:02:01 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:02:02 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:03 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- A-- --- --- --- --- --- --- DOB*01:04:01:01 --- --- --- --- --- --- --- --- T-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:04:01:02 --- --- --- --- --- --- --- --- T-- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- DOB*01:05 --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- cDNA 751 AA codon 225 | DOB*01:01:01:01 AAA G|GA TAT GTG AGG ACG CAG ATG TCT GGT AAT GAG |GTC TCA AGA GCT GTT CTG CTC CCT CAG TCA TGC TAA G DOB*01:01:01:02 --- -|-- --- --- --- --- --- --- --- --- --- --- |--- --- --- --- --- --- --- --- --- --- --- --- - DOB*01:01:01:03 --- -|-- --- --- --- --- --- --- --- --- --- --- |--- --- --- --- --- --- --- --- --- --- --- --- - DOB*01:01:01:04 --- -|-- --- --- --- --- --- --- --- --- --- --- |--- --- --- --- --- --- --- --- --- --- --- --- - DOB*01:01:02 --- -|-- --- --- --- --- --- --- --- --- --- --- |--- --- --- --- --- --- --- --- --- --- --- --- - DOB*01:01:03:01 --- -|-- --- --- --- --- --- --- --- --- --- --- |--- --- --- --- --- --- --- --- --- --- --- --- - DOB*01:01:03:02 --- -|-- --- --- --- --- --- --- --- --- --- --- |--- --- --- --- --- --- --- --- --- --- --- --- - DOB*01:02:01 --- -|-- --- --- --- --- --- --- --- --- --- --- |--- --- --- --- --- --- --- --- --- --- --- --- * DOB*01:02:02 --- -|-- --- --- --- --- --- --- --- --- --- --- |--- --- --- --- --- --- --- --- --- --- --- --- - DOB*01:03 --- -|-- --- --- --- --- --- --- --- --- --- --- |--- --- --- --- --- --- --- --- --- --- --- --- * DOB*01:04:01:01 --- -|-- --- --- --- --- --- --- --- --- --- --- |--- --- --- --- --- --- --- --- --- --- --- --- - DOB*01:04:01:02 --- -|-- --- --- --- --- --- --- --- --- --- --- |--- --- --- --- --- --- --- --- --- --- --- --- - DOB*01:05 --- -|-- --- --- --- --- --- --- --- --- --- --- |--- --- --- --- --- --- --- --- --- --- --- --- - cDNA 824 AA codon 249 | DOB*01:01:01:01 DOB*01:01:01:02 DOB*01:01:01:03 DOB*01:01:01:04 DOB*01:01:02 DOB*01:01:03:01 DOB*01:01:03:02 DOB*01:02:01 DOB*01:02:02 DOB*01:03 DOB*01:04:01:01 DOB*01:04:01:02 DOB*01:05 Please see http://hla.alleles.org/terms.html for terms of use.